CAS: 5751-83-7; Ethyl 5-Bromothiophene-2-Carboxylate

上下游产品

CAS号7311-63-9 5-溴噻吩-2-甲酸 | CAS号3141-27-3 2,5-二溴噻吩 | CAS号623-49-4 氰基甲酸乙酯 | CAS号4701-17-1 5-溴噻吩-2-甲醛 | CAS号64-17-5 乙醇 | CAS号1609-47-8 焦碳酸二乙酯 | CAS号2810-04-0 噻吩-2-羧酸乙酯 | CAS号31555-60-9 5-溴噻吩-2-甲酰氯 | CAS号1003-09-4 2-溴噻吩 | CAS号56-23-5 四氯化碳 | CAS号4701-17-1 5-溴噻吩-2-甲醛 | CAS号2160-52-3 Ethyl 5-bromo-4... | CAS号98027-27-1 5-溴噻吩-2-甲酰肼 | CAS号890100-51-3 ETHYL 5-THENOYL... | CAS号7311-63-9 5-溴噻吩-2-甲酸 | CAS号115933-30-7 5-(4-氟苯基)噻吩-2-甲酸 | CAS号13858-71-4 5-(4-甲硫基苯基)噻吩-2-羧酸乙酯 | CAS号31555-60-9 5-溴噻吩-2-甲酰氯 | CAS号19282-40-7 Ethyl 5-(4-chlo... | CAS号186521-39-1 ETHYL 5-[(3R)-4...

2-噻吩羧酸乙酯置于zinc(II) Chloride Benzyltrimethylazanium Tribroman-2-Uide体系中,用 溶剂黄146 作为反应溶剂,化学反应 17.0H,以86%的收率获得产物5-溴噻吩-2-甲酸乙酯
参考文献:使用季铵多卤化物的卤化.xxxi 噻吩衍生物与苄基三甲基多卤化铵的卤化
标题:使用季铵多卤化物的卤化.xxxi 噻吩衍生物与苄基三甲基多卤化铵的卤化
摘要:噻吩衍生物与四氯碘酸苄基三甲基铵,三溴化苄基三甲基铵,二氯碘酸苄基三甲基铵在乙酸或乙酸中的反应...
DOI:10.1246/bcsj.64.2566

专利信息

专利号:US-5981748-A
优先权日:1995-06-07
标题:Synthesis of optically pure compounds useful as GARFT inhibitors and their intermediates
发明人：VARNEY MICHAEL D; ROMINES WILLIAM H; PALMER CYNTHIA L
权利人:AGOURON PHARMA
摘要:The invention relates to methods of making compounds of the formula VII ##STR1## and their enantiomers, where Ar is a substituted or unsubstituted five- or six-membered aromatic group and B is either an amino acid linked through the amino portion to form an amide or a C 1 -C 6 alcohol linked through the alcohol portion to form an ester. These compounds are advantageously employed as intermediates to prepare optically pure compounds that are active GARFT inhibitors. In one method, a compound of the formula ##STR2## is reacted with a compound of the formula ##STR3## where X is a halogen.

专利号:DE-69629703-T2
优先权日:1995-06-07
标题 :SYNTHESIS OF OPTICALLY PURE COMPOUNDS AS GARFT INHIBITORS AND THEIR INTERMEDIATE PRODUCTS

专利号:WO-2010065383-A1
优先权日:2008-11-25
标 题 :Calcilytic compounds
发明人：CASILLAS LINDA N; CHARNLEY ADAM KENNETH; HARRIS PHILIP ANTHONY; JEONG JAE U; MARQUIS ROBERT W; RAMANJULU JOSHI M; TROUT ROBERT
权利人:GLAXOSMITHKLINE LLC; CASILLAS LINDA N; CHARNLEY ADAM KENNETH; HARRIS PHILIP ANTHONY; JEONG JAE U; MARQUIS ROBERT W; RAMANJULU JOSHI M; TROUT ROBERT
摘要:Novel calcilytic compounds, pharmaceutical compositions, methods of synthesis and methods of using them are provided.

专利号:US-2010010219-A1
优先权日:2006-12-07
标 题 :Method for producing pyrrolidine compound
发明人：HARADA KAZUHITO; ITO TAKASHI
权利人:JAPAN TOBACCO INC
摘要:Provided is a method capable of efficiently producing a compound having a superior HSD1 inhibitory action and a compound useful as a synthetic intermediate therefor, with superior achievability of asymmetric synthesis (i.e., superior selectivity), superior yield, superior safety and superior industrial workability at a low cost. n A method of producing a compound represented by the following formula [8]: n n n n n n n n n n or a salt thereof, or a solvate thereof, from a compound represented by the following formula [2]: n n n n n n n n n n or a reactive derivative thereof, or a salt thereof, or a solvate thereof.

专利号:CN-116023359-B
优先权日:2022-12-29
标题:A kind of synthesis method of aminothiophene compound and aminothiophene compound

专利号:CN-116023359-A
优先权日:2022-12-29
标 题 :Synthesis method of aminothiophene compound and aminothiophene compound