相似化合物
195604-39-8 195252-68-7 178033-78-8欧盟法规
C&L通报专利信息
专利号:EP-4217339-A1
优先权日:2020-09-26
标题:A process for the synthesis of anthranilic acid/amide compounds and intermediates thereof
专利号:CA-3191922-A1
优先权日:2020-09-26
标 题:A process for the synthesis of anthranilic acid/amide compounds and intermediates thereof
专利号:IL-301294-A
优先权日:2020-09-26
标题 :A process for the synthesis of anthranilic acid/amide compounds and intermediates thereof
专利号:WO-2024179572-A1
优先权日:2023-03-01
标题:Aromatic-ring compound and use thereof
发明人:LI JIN; WANG QINGYANG; WANG XIAOTAO; LI XIAOMEI; DOU DENGFENG; MENG XIAOYUN; LI XIANYANG; CHEN QIUXIA; GUO ANPING; Zheng nuo; HU HONG; HE WEI
权利人:HITGEN INC
摘要:Provided are a new compound having a binding effect on the E3 ligase protein TRIM21, and the use thereof in the preparation of a drug for treating abnormal cell proliferation diseases. Further provided is an intermediate compound in the synthesis process of a proteolysis-targeting bifunctional compound.
专利号:WO-2025055006-A1
优先权日:2023-09-13
标 题 :Matrine derivative, preparation method therefor, and use thereof
发明人:ZHANG JIE; CHEN TINGZHUO; RONG BO; QIAN SHAN; TANG QINGQING; DU BO; WU YUXIANG; REN DAN; HE QIMING
权利人:CHENGDU NEWSUN CROP SCIENCE CO LTD
摘要:The present application relates to the field of organic synthesis. Disclosed are a matrine derivative, a preparation method therefor, and a use thereof. By taking sophora acid methyl ester as a raw material, a nucleophilic substitution or nucleophilic addition reaction is carried out under an alkaline condition, to obtain a series of new matrine derivatives in one step. The matrine has certain insecticidal activity, but the insecticidal effect is not ideal; however, the activity of the matrine is multiplied by modifying the structure of the matrine and is obviously superior to that of the matrine before structural modification; in addition, some compounds also have an inhibitory effect on the activity of SIRT enzymes.