专利号:US-10793495-B2 优先权日:2015-08-14 标 题:Synthesis of polyaryl substituted aryl compounds 发明人:BOULOS RAMIZ; FEUTRILL JOHN 权利人:BOULOS & COOPER PHARMACEUTICALS PTY LTD 摘要:A method for the synthesis of a aryl compound of Formula (1).n nU T-W—R 1 ) n    (1)
专利号:US-4049710-A 优先权日:1976-02-24 标题:Novel carbamimidoyl chlorides and their use in the synthesis of herbicidal triazinediones 发明人:TOCKER STANLEY 权利人:DU PONT 摘要:Carbamimidoyl chlorides of the formula: WHERE R2 is alkyl of 1-4 carbon atoms are useful as intermediates in the synthesis of herbicidal triazinediones of the formula: where R1 is certain organic radicals.
专利号:US-7615638-B2 优先权日:2006-04-28 标题 :Synthesis of grossularines-1 and analogs thereof and method of use 发明人:HORNE DAVID A; JOVE RICHARD; NAM SANGKIL; YAKUSHIJIN KENICHI; YAKUSHIJIN FUMIKO Y 权利人:HOPE CITY 摘要:In one embodiment of the present invention, a synthesis of grossularine-1 and N,N-didesmethylgrossularine-1 2 and analogs thereof based on a novel oxidative dimerization-electrocyclization sequence of 2-amino-4-(3-indolyl)imidazoles derived from oxotryptamine 3 is described.
专利号:US-9738647-B2 优先权日:2009-12-24 标题:Methods for the synthesis of polycyclic guanidine compounds 发明人:GRIDNEV ALEXEI 权利人:NOVOMER INC; SAUDI ARAMCO TECH CO 摘要:The present invention provides methods for the synthesis of polycyclic guanidine compounds. In certain embodiments, provided methods include the step of contacting a described reagent with a triamine compound to provide a polycyclic guanidine compound.
专利号:US-4918173-A 优先权日:1985-07-02 标 题 :2',6'-Dideoxy derivatives of anthracycline glycosides 发明人:MONNERET CLAUDE; FLORENT JEAN-CLAUDE; GENOT AGNES 权利人:HOECHST SA LAB 摘要:The present invention relates to new tetralins and their use for the preparation of anthracyclinones and anthracyclins. These tetralins contain at least one chiral carbon atom and correspond to the formula (V) below: (V) in which: R1 and R2 denote a hydrogen atom, or a halogen atom or the group OCH3, provided that one of the two substituents (R1 or R2) must denote OCH3, and R3 denotes a hydrogen atom or the OR' group, R' being hydrogen or a hydroxyl-protecting group. Application: synthesis of glycosides of great therapeutic value.
专利号:US-3681297-A 优先权日:1970-11-10 标 题 :Synthesis of polybenzothiazolines and polybenzothiazoles by reacting a dialdehyde with an aromatic bis-mercaptoamine 发明人:ALELIO GAETANO FRANCIS D 权利人:GAETANO FRANCIS D ALELIO 摘要:THIS INVENTION DEALS WITH A NOVEL, RELATIVELY SIMPLE PROCESS OF PREPARING POLYBENZOTHIAZOLINES, ((-NH-CH(-)-S-)>AR<(-NH-CH(-Z(-))-S-))N BY REACTING DIALDEHYDES, Z-(CH=O)2, AND (HS)2-AR(-NH2)2 IN A SOLVENT IN AN INERT ATMOSPHERE AND THEREAFTER OXIDIZING THE POLYBENZOTHIAZOLINES TO POLYBENZOTHIAZOLES, ((-N=C(-)-S-)>AR<(-N=C(-Z(-))-S-))N WHEREIN AR REPRESENTS A TETRAVALENT AROMATIC MOIETY IN WHICH THE NITROGEN AND SULFUR ATOMS IN EACH PAIR ARE DISPOSED ORTHO TO EACH OTHER AND Z REPRESENTS A DIVALENT HYDROCARBON MOIETY AS THE RESIDUE OF THE DIALDEHYDE, Z(CHO)2. NEW TYPES, AS WELL AS THE KNOW TYPES OF POLYBENZOTHIAZOLES HAVE BEEN PREPARED BY THIS PROCESS.