相似化合物
52200-48-3 97966-00-2 1184917-16-5欧盟法规
ECHA物质C&L通报上下游产品
CAS号137628-16-1 3-溴-5-氯-2-羟基吡啶 | CAS号1072-98-6 2-氨基-5-氯吡啶 | CAS号26163-03-1 2-氨基-3-溴-5-氯吡啶 | CAS号4214-79-3 5-氯-2-吡啶醇 | CAS号202409-82-3 2-(Benzyloxy)-3... | CAS号59782-85-3 2,5-二氯烟酸合成工艺路线路线简述
- 1221793-62-9 = 138006-41-4 + 97966-00-2
反应条件:1.1 Reagents: Triethylamine Solvents: Dichloromethane; Rt -> -70 °C1.2 Reagents: Oxalyl Chloride; -70 °C; 30 Min,-70 °C1.3 Reagents: Methanol
标题:Highly Regioselective Halogenation Of Pyridine N-Oxide: Practical Access To 2-Halo-Substituted Pyridines
作者:Chen,Ying; Huang,Jinkun; Hwang,Tsang-Lin; Chen,Maosheng J.; Tedrow,Jason S.; Et Al
参考文献:Organic Letters 日期:2015 卷标:17(12) 页码:2948-2951
3-溴-5-氯-2-羟基吡啶置于三氯氧磷体系中,用 N,N-二甲基甲酰胺 用作溶剂,以81.76 G (89%)的收率获得2,5-二氯-3-溴吡啶
参考文献:6-Chloro-3,4-Dihydro-Pyrano [2,3-B]Pyridines Having The R Configuration
标题:6-Chloro-3,4-Dihydro-Pyrano [2,3-B]Pyridines Having The R Configuration
摘要:本发明涉及用于制备螺环杂异唑酮的过程和中间体.后者化合物可用作醛糖还原酶抑制剂.
专利信息
专利号:US-2013072495-A1
优先权日:2010-05-14
标 题 :Fused bicyclic kinase inhibitors
发明人:LI AN-HU; MULVIHILL MARK J; STEINIG ARNO G
权利人:LI AN-HU; MULVIHILL MARK J; STEINIG ARNO G; OSI PHARMACEUTICALS LLC
摘要:Compounds of Formula I, as shown below and defined herein: pharmaceutically acceptable salts thereof, synthesis, intermediates, formulations, and methods of disease treatment therewith, including treatment of cancers, such as but not limited to tumors driven at least in part by at least one of RON, MET, IR, IGF-1R, or ALK. This Abstract is not limiting of the invention.
专利号:US-8445510-B2
优先权日:2010-05-14
标题 :Fused bicyclic kinase inhibitors
发明人:MULVIHILL MARK J; STEINIG ARNO G; CREW ANDREW PHILIP; JIN MEIZHONG; KLEINBERG ANDREW; LI AN-HU; WANG JING
权利人:MULVIHILL MARK J; STEINIG ARNO G; CREW ANDREW PHILIP; JIN MEIZHONG; KLEINBERG ANDREW; LI AN-HU; WANG JING; OSI PHARMACEUTICALS LLC
摘要:Compounds of Formula I, as shown below and defined herein: n n n n n n n n n n pharmaceutically acceptable salts thereof, synthesis, intermediates, formulations, and methods of disease treatment therewith, including treatment of cancers, such as tumors driven at least in part by at least one of RON, MET or ALK. This Abstract is not limiting of the invention.