专利号:US-2022220061-A1 优先权日:2019-05-09 标 题:Process for the synthesis of the ionic liquid tetraoctylammonium di(2-ethylhexyl)-oxamate (il-5), product obtained and its use in selective metal extraction 发明人:ARRIEGAS ESTEVÃO CORREIA LEAL JOÃO PAULO; DA CUNHA OLIVEIRA FIGUEIRA CARRETAS JOSÉ MANUEL; MARIA CRUZ ADELAIDE; DE JESUS MARIA LEONOR MARIA; RAMOS BATISTA MONTEIRO BERNARDO 权利人:INST SUPERIOR TECNICO 摘要:a) The present invention falls within the area of the synthesis of ionic liquids, namely it concerns a process of synthesis of the ionic liquid tetraoctylammonium di(2-ethylhexyl)-oxamate (IL-5) with a high degree of purity and its use in the extraction and selective separation of metals, namely lanthanides. Thus, it is the object of the present invention, a process for the synthesis of a pure ionic liquid using in its constitution only the elements carbon, hydrogen, oxygen and nitrogen (CHON), assuming itself as a “greenâ€? alternative in the recovery of metals, thus reducing the environmental impact in the way they are recovered, as well as the guarantee of a more efficient extraction of these metals.
专利号:WO-2020226521-A1 优先权日:2019-05-09 标题:Process for the synthesis of the ionic liquid tetraoctylammonium dioctyl-diglycolamate (il-4), product obtained and its use in metal remediation 发明人:ARRIEGAS ESTEVÃO CORREIA LEAL JOÃO PAULO; DA CUNHA OLIVEIRA FIGUEIRA CARRETAS JOSÉ MANUEL; MARIA CRUZ ADELAIDE; DE JESUS MARIA LEONOR MARIA; RAMOS BATISTA MONTEIRO BERNARDO 权利人:INST SUPERIOR TECNICO 摘要:The present invention falls within the area of the synthesis of ionic liquids, namely it concerns a process of synthesis of the ionic liquid tetraoctylammonium dioctyl-diglycolamate (IL-4) with a high degree of purity and its use in an environmental remediation process of lanthanides and actinides. In addition, it is also an object of the present invention to obtain the ionic liquid tetraoctylammonium dioctyl-diglycolamate (IL-4) with a high degree of purity that allows the separation and sequestration of metals with a high efficiency.
专利号:US-7241900-B2 优先权日:2002-02-12 标题 :Synthesis of indole thiazole compounds as ligands for the Ah receptor 发明人:DELUCA HECTOR F; GRZYWACZ PAWEL K; SICINSKI RAFAL R 权利人:WISCONSIN ALUMNI RES FOUND 摘要:A method of synthesizing aromatic ketone compositions of formula I comprising the step of introducing a double bond into the 5 membered ring of the 4,5-dihydro-1,3-azoles moiety of formula II is disclosed. A method of synthesizing aromatic ketone compositions of formula I comprising the step of ring synthesis of the tetrahydro-1,3-azoles of formula XI is also disclosed.
专利号:US-10266565-B2 优先权日:2011-04-12 标 题 :Peptide mimetic ligands of polo-like kinase 1 polo box domain and methods of use 发明人:BURKE JR TERRENCE R; LIU FA; LEE KYUNG S; PARK JUNG-EUN 权利人:BURKE JR TERRENCE R; LIU FA; LEE KYUNG S; PARK JUNG EUN; THE US SECRETARY DEPARTMENT OF HEALTH & HUMAN SERVICES 摘要:Novel compounds are provided that bind to polo-like kinases through the polo-box domain. In certain embodiments, the novel compounds are PEGylated peptides. The PEGylated peptides in accordance with the invention demonstrate high PBD-binding affinity. In certain embodiments, the PEGylated peptides have also achieved activities in whole cell systems. The invention also provides compounds that bind polo-like kinases through the polo-box domain and possess reduced anionic charge. Further provided are methods of design and/or synthesis of the PEGylated peptides and methods of use thereof. The invention provides methods of use of the compounds and methods of synthesis of the compounds.
专利号:US-10040752-B2 优先权日:2015-08-24 标 题 :Synthesis of levomethadone hydrochloride or dextromethadone hydrochloride and methods for use thereof 发明人:MKRTCHYAN GNEL; YAO QINGWEI 权利人:CODY LABORATORIES INC 摘要:Highly efficient methods for synthesis of levomethadone hydrochloride or dextromethadone hydrochloride are provided starting from D-alanine, or L-alanine, respectively, with retention of configuration. Methods for treating a subject are provided comprising administering a composition comprising an effective amount of levomethadone hydrochloride having not more than 10 ppm dextromethadone.
专利号:US-8128902-B2 优先权日:2011-04-12 标题:Method for the synthesis of anhydrous hydrogen halide and anhydrous carbon dioxide 发明人:TARANCON III GREGORIO 权利人:TARANCON III GREGORIO; MIDWEST REFRIGERANTS LLC 摘要:A method for the synthesis of anhydrous hydrogen halide fluids from organic halide fluids, such as perfluorocarbon fluids and refrigerant fluids, and anhydrous carbon dioxide for the environmentally safe disposition thereof.
摘要:Hites, R.A. Handbook of Mass Spectra of Environmental Contaminants. Boca Raton, FL: CRC Press Inc., 1985., p. 380 摘要:IARC. Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans. Geneva: World Health Organization, International Agency for Research on Cancer, 1972-PRESENT. (Multivolume work).