CAS: 74338-24-2; 2,3,3',4-Tetrachloro-1,1'-Biphenyl

该化合物是一种主要用于研究和工业应用的氯化双联苯化合物,由于其稳定的化学结构,主要用于研究和工业应用;作为多氯联苯(PCB)家族的成员,它具有较高的热和化学抗药性,因此适合环境持久性和降解途径的研究;其定义明确的分子结构可以进行精确的分析应用,包括色谱和质谱测量中的校准标准;该化合物还被用于毒理学研究,以调查多氯联苯对生物系统的影响;适当处理由于其潜在的环境和健康危害至关重要;高纯度配方可以确保科学和工业环境中的可靠性能.

英文名称2,3,3',4-Tetrachloro-1,1'-Biphenyl
中文名称2,3,3',4-四氯-1,1'-联苯
IUPAC名称1,2,3-trichloro-4-(3-chlorophenyl)benzene
其它别名2,3,3',4-四氯联苯; 2,3,3',4-Tetrachlorobiphenyl
CAS编号74338-24-2
MFCD编号:MFCD00152841
FDA UNII编号:T34626QGG0
分子式:C12H6Cl4分子量:291.99
产品CID: 1733016
产品分类有机原料→分子砌块→芳环类化合物→苯类化合物

相似结构搜索
产品信息参考;;;;
InChIKey: ZKGSEEWIVLAUNH-UHFFFAOYSA-N
1S/C12H6Cl4/c13-8-3-1-2-7(6-8)9-4-5-10(14)12(16)11(9)15/h1-6H
计算化学: 氢键受体数*氢键供体数*可旋转键数1.0

MSDS等安全信息

GHS符号GHS07
警示词Warning
危险描述H302-H315-H319-H335
防范说明P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
安全声明The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcription of genes, mainly be inducing the expression of hepatic Phase I and Phase II enzymes, especially of the cytochrome P450 family. Most of the toxic effects of PCBs are believed to be results of Ah receptor binding. Other PBCs are believed to interfere with calcium channels and/or change brain dopamine levels. PCBs can also cause endocrine disurption by altering the production of thyroid hormones and binding to estrogen receptors, which can stimulate the growth of certain cancer cells and produce other estrogenic effects, such as reproductive dysfunction. They will bioaccumulate by binding to receptor proteins such as uteroglobin. (A3, A4, A30, A66)

上下游产品

3-iod°Chlorobenzene 1,2,3-trichloro-4-iodobenzene

合成工艺路线路线简述

📜1-氯-3-碘苯,2,3,4-三氯碘苯置于铜体系中,用 N,N-二甲基甲酰胺作为反应溶剂,化学反应生成 2,3,3',4-四氯联苯
参考文献:Physical,Spectral And Chromatographic Properties Of All 209 Individual Pcb Congeners
标题:Physical,Spectral And Chromatographic Properties Of All 209 Individual Pcb Congeners
摘要:Physical,Spectral And Chromatographic Data For All 209 Individual Pcb Congeners Is Presented. The Individual Congeners Were Synthesized And Then Isolated And Purified. Recent Emphasis On The Source Of The Toxicity Of Commercial Pcb Formulations Has Increased The Need For A Complete Set Of The Pcb Congeners. Through The Use Of Two Capillary Gc Columns: 40% octadecyl/ 15% Phenyl Methyl Siloxane And 50% Phenyl Methyl Siloxane,It Was Possible To Separate 201 Pcb Congeners With Only Four Unresolved Pairs. The Data Compiled In This Study For All 209 Congeners Will Aid In The Identification Of Selected Individual Components Of These Environmental Pollutants. The Use Of This Data Also Presents The Opportunity For The Improved Quantification Of The Commercial Pcb Formulations.
DOI:10.1016/0045-6535(95)00140-4