合成目标产物 Dimethyl Itaconate 主要起始原料 Methanol And Itaconic Acid
(文献来源)合成步骤主要原料 Methanol 和 Itaconic Acid
甲基丁二酸二甲酯置于铑体系中,化学反应生成 衣康酸二甲酯 参考文献:Ferrocenyl-1,2-Diphosphines,The Production Thereof And Their Use 标题:Ferrocenyl-1,2-Diphosphines,The Production Thereof And Their Use 摘要:该发明涉及公式(i)的化合物,以外消旋化合物,对映异构体混合物或基本纯的对映异构体的形式提供,其中r1代表氢原子或c1-C4-烷基,并且至少一个二级膦代表未取代或取代的环膦基团,或具有一或两个一价阴离子或二价阴离子的膦盐.公式(i)的化合物可以通过一种新方法获得,并且是在不对称合成中具有催化活性的金属配合物的有价值的配体.
专利号:WO-2024012791-A1 优先权日:2022-07-11 标题 :Electrochemical synthesis of pyrazolines and pyrazoles 发明人:BÄR ROBIN MAXIMILIAN; FORD MARK JAMES; KALDAS SHERIF JAMES; WALDVOGEL SIEGFRIED; HOFMANN SILJA; LINDEN MARTIN 权利人:BAYER AG 摘要:The present invention relates to an electrochemical process for the synthesis of pyrazolines and pyrazoles of formula (I). The process can be especially used for the synthesis of the herbicide safener mefenpyr-diethyl.
专利号:US-7189849-B2 优先权日:1997-02-10 标 题:Synthesis of acyclic nucleoside derivatives 发明人:LEANNA M ROBERT; RASMUSSEN MICHAEL; HANNICK STEVEN M; TIEN JIEN-HEH J; LUKIN KIRILL A; TIAN ZHENPING; CHANG SOU-JEN; CURTY CYNTHIA B; NARAYANAN BIKSHANDARKOIL A; BELLETTINI JOHN; SHELAT BHADRA; SPITZ TIFFANY 权利人:MEDIVIR AB 摘要:Novel processes towards the synthesis of the antiviral valomaciclovir stearate in which an esterified guanine acetal is reduced to the corresponding alcohol, reacted with an activated amino acid and N-deprotected. The esterified guanine acetal is prepared from a 9-guanine derivative bearing an acyclic hydroxymethylbutylacetal. The processes are amendable to one-pot reactions.
专利号:US-6100350-A 优先权日:1996-02-23 标题 :Branched polymer synthesis 发明人:WILCZEK LECH; MCCORD ELIZABETH FORRESTER 权利人:DU PONT; COMMW SCIENT IND RES ORG 摘要:PCT No. PCT/US97/02913 Sec. 371 Date Aug. 19, 1998 Sec. 102(e) Date Aug. 19, 1998 PCT Filed Feb. 18, 1997 PCT Pub. No. WO97/31031 PCT Pub. Date Aug. 28, 1997This invention relates to a process for the synthesis of addition polymers containing branches upon branches and having a polymerizable olefin end group by a convenient one-pot copolymerization of selected vinyl monomers with chain polymerization initiators and a method to provide olefin end groups by chain transfer or termination agents; and polymers produced thereby.
专利号:WO-2018186744-A1 优先权日:2017-04-05 标 题 :Synthesis and use of carbohydrate-based linear polyesters 发明人:PICCHIONI FRANCESCO; GAVRILA IONELA 权利人:UNIV GRONINGEN 摘要:The invention relates to the field of polymer chemistry, more in particular to the synthesis of novel biobased linear polymers and their applications, among others as rheology modifiers or thickeners in waterborne formulations. Provided is a method for providing a linear carbohydrate-based polyester, comprising (i) reacting a bicyclic acetalized galactaric acid derivative (Galx) with a diol in the presence of a suitable catalyst to obtain a Galx -based polyester; and (ii) subjecting said Galx -based polyester to a hydrolytic deacetalisation reaction to convert at least part of the diacetal moieties to chhydroxide moieties.
专利号:US-2025115551-A1 优先权日:2023-10-03 标 题:Synthesis of ras inhibitors 发明人:LI YI; MENDOZA BENJAMIN; NAGANATHAN SRIRAM; WANG ROSS; YI YI; BALLMER STEVEN G; DAVIDSON JAMES; HUANG XIAOJUN 权利人:REVOLUTION MEDICINES INC 摘要:The present invention relates to Ras inhibitors, intermediates in the synthesis thereto, and methods for preparing the Ras inhibitors and the intermediates.
专利号:US-10040964-B2 优先权日:2014-02-12 标题:Use of tristyrylphenol alkoxylate sulfosuccinates in emulsion polymerization and coatings 发明人:LUEBKE GARY; RESCHAK KEITH; LUKA RENEE; KALTENBACH JARROD 权利人:STEPAN CO 摘要:Disclosed are the use of novel surfactants for the synthesis of emulsion polymer latexes, particularly those used in paints, coatings, and pressure sensitive adhesives. The surfactant compositions for emulsion polymer latexes comprise sterically bulky surfactants whose composition comprises at least one alkoxylated polyaryl substituted aromatic sulfosuccinate compound. The novel surfactants provide for the production of stable, small particle size distribution emulsion polymer latexes. The resulting latexes, when formulated into latex paint, impart improvements in water resistance as measured by film opacity, blister resistance and improved leveling characteristics, and when formulated into pressure sensitive adhesives, provide improved water resistance characteristics as measured by film opacity.
[参考文献]: T. V. Rajanbabu, Et Al. Electronic Effects In Asymmetric Catalysis: Structural Studies Of Precatalysts And Intermediates In Rh-Catalyzed Hydrogenation Of Dimethyl Itaconate And Acetamidocinnamic Acid Derivatives Using C(2)-Symmetric Diarylphosphinite Ligands. J Org Chem. 1999 May 14;64(10):3429-3447.
合成参考文献
摘要:Stephenson, G. R., Science of Synthesis Knowledge Updates, (2014) 1, 215. 摘要:Silva, V. L. M.; Pinto, D. C. G. A.; Santos, C. M. M.; Rocha, D. H. A., Science of Synthesis Knowledge Updates, (2022) 3, 201. 摘要:Ager, D., Science of Synthesis: Stereoselective Synthesis, (2011) 1, 231. 摘要:Andersson, C.-M.; Andersson, M., Science of Synthesis: Cross Coupling and Heck-Type Reactions, (2012) 3, 8. 摘要:Makida, Y.; Kuwano, R., Science of Synthesis: N-Heterocyclic Carbenes in Catalytic Organic Synthesis, (2016) 1, 266.