CAS: 608-05-9; 5-Methylindoline-2,3-Dione

上下游产品

CAS号302-17-0 水合氯醛 | CAS号106-49-0 对甲苯胺 | CAS号1132-40-7 2-羟基亚氨基对甲苯乙酰胺 | CAS号201230-82-2 carbon monoxide | CAS号58226-34-9 N'-(2-Bromo-4-m... | CAS号79-37-8 草酰氯 | CAS号5470-11-1 盐酸羟胺 | CAS号29650-23-5 5-methyl-indoli... | CAS号583-68-6 2-溴-4-甲基苯胺 | CAS号108053-80-1 5-methyl-1-[3-(... | CAS号3484-35-3 5-甲基吲哚啉-2-酮 | CAS号1955-61-9 2,4-Quinazoline... | CAS号1908-01-6 5-甲基-1H-吲唑-3-羧酸乙酯 | CAS号4692-99-3 6-甲基靛红酸酐 | CAS号2941-79-9 苏沃雷生杂质B | CAS号2437-73-2 2,3,6-Trimethyl... | CAS号5925-93-9 2-氨基-5-甲基苯腈 | CAS号13208-98-5 (3Z)-5-甲基-1H-吲哚... | CAS号104175-33-9 2,6-二甲基喹啉-4-羧酸

4-甲基苯胺盐酸盐置于硫酸,盐酸羟胺,Sodium Sulfate体系中,用 水 作为反应溶剂,化学反应 10.17H,反应生成 5-甲基靛红
参考文献:Gupta,Neeti; Singh,Indian Journal Of Chemistry,Section A: Inorganic,Physical,Theoretical And Analytical,1998,Vol. 37,# 1,P. 75-79
标题:Gupta,Neeti; Singh,Indian Journal Of Chemistry,Section A: Inorganic,Physical,Theoretical And Analytical,1998,Vol. 37,# 1,P. 75-79

专利信息

专利号:US-9328061-B2
优先权日:2012-03-01
标题:Simple organic molecules as catalysts for practical and efficient enantioselective synthesis of amines and alcohols
发明人：HOVEYDA AMIR H; SILVERIO DANIEL L; PILYUGINA TATIANA; TORKER SEBASTIAN; ROBBINS DANIEL
权利人:TRUSTEES BOSTON COLLEGE
摘要:The present invention provides organic molecules and methods thereof for reactions between organoboron reagents and double bonds, such as imines or carbonyls, to stereoselectively provide chiral products including amines and alcohols, entities useful for the preparation of biologically active molecules.

专利号:WO-9948868-A9
优先权日:1998-03-26
标 题 :Heterocyclic classes of compounds for the modulating tyrosine protein kinase
发明人：FONG ANNIE; HANNAH ALISON; HARRIS G DAVIS; HIRTH PETER; HUBBARD STEVEN R; LANGECKER PETER; LIANG CONGXIN; MCMAHON GERALD; MOHAMMADI MOOSA; SCHLESSINGER JOSEPH; SHAWVER LAURA K; SUN LI; TANG PENG C; ULLRICH AXEL
权利人:SUGEN INC; UNIV NEW YORK; MAX PLANCK INST FUR BIOCHEMIE; FONG ANNIE; HANNAH ALISON; HARRIS G DAVIS; HIRTH PETER; HUBBARD STEVEN R; LANGECKER PETER; LIANG CONGXIN; MCMAHON GERALD; MOHAMMADI MOOSA; SCHLESSINGER JOSEPH; SHAWVER LAURA K; SUN LI; TANG PENG C; ULLRICH AXEL
摘要:The invention relates to certain indolinone-based and pyrazolylamide-based compounds, their method of synthesis, and combinatorial libraries consisting of the compounds. The invention also relates to methods of modulating the function of protein kinases using these compounds and methods of treating diseases by modulating the function of protein kinases and related signal transduction pathways.

专利号:WO-0053313-A2
优先权日:1999-03-09
标 题:Lanthanide catalysts for synthesis of compounds and combinatorial libraries

专利号:US-8497296-B2
优先权日:2011-03-31
标 题:N,N′-hydrazino-bis-isatin derivatives with selective activity against multidrug-resistant cancer cells
发明人：HASSAN TAREK ABOUL-FADL MOHAMED; KADI ADNAN AHMED; ABDEL-AZIZ HATEM ABDEL-KHADER
权利人:HASSAN TAREK ABOUL-FADL MOHAMED; KADI ADNAN AHMED; ABDEL-AZIZ HATEM ABDEL-KHADER; UNIV KING SAUD
摘要:The invention is directed to a compound of Formula (I), n nwherein R is selected from the group consisting of hydrogen atom and unsubstituted or substituted phenyl group; R 1 is selected from the group consisting of hydrogen atom and unsubstituted or substituted phenyl group; X is selected from the group consisting of hydrogen atom or halogen atom; and Y is selected from the group consisting of hydrogen atom, halogen atom, C 1 -C 4 alkyl group, nitro group, and —OCF 3 group, as well as for its use in therapy, preferably for the treatment of cancer, and to a related pharmaceutical composition, the use of the compound for the manufacture of a medicament for the respective medical indication, and a method of synthesis of the compounds of the invention.

专利号:US-2004067531-A1
优先权日:1997-08-20
标 题:Methods of modulating protein tyrosine kinase function with substituted indolinone compounds
发明人：TANG PENG CHO; SUN LI; TRAN NGOC MY; NGUYEN ANH THI; NEMATALLA ASAAD
权利人:SUGEN INC
摘要:The invention relates to certain indolinone compounds, their method of synthesis, and a combinatorial library consisting of the indolinone compounds. The invention also relates to methods of modulating the function of protein tyrosine kinases using indolinone compounds and methods of treating diseases by modulating the function of protein tyrosine kinases and related signal transduction pathways.

专利号:US-8933248-B2
优先权日:2012-06-21
标 题:3-substituted-3-hydroxy oxindole derivatives and process for preparation thereof
发明人：RAO MANDAPATI MOHAN; PRATHIMA PARVATHANENI SAI
权利人:COUNCIL SCIENT IND RES
摘要:The present invention relates to expedient method for synthesis of 3-substituted-3-hydroxy-oxindole derivatives, which are useful as synthetic precursors to valuable pharmaceutical compounds. These are synthesized by reacting nitromethane with the corresponding isatins of formula (I). The reaction process of isatins was carried using water as a solvent at room temperature to form the corresponding 3-hydroxy-3-nitromethylindolin-2-ones of formula (II).