CAS: 579-18-0; 3-Benzoylbenzoic Acid

上下游产品

phosgene benzophenone 3-benzylbenzoic acid 3-methyl benzophenone 3-benzoylbenzoyl chloride 3-(α-hydroxy-benzyl)-benzoic acid m-benzoylbenzoic acid methyl ester 3-Benzoyl-N-hydroxy-benzamide

1-苄基-3-甲基苯置于potassium Bromate,Cerium (Iv) Ammonium Nitrate,溶剂黄146体系中,化学反应 24.0H,以71%的收率获得产物3-苯甲酰苯甲酸
参考文献:超声促进了barbier反应和csp3-Csp2 Stille偶联,用于合成二芳基甲烷和取代的二苯甲酮.
标题:超声促进了barbier反应和csp3-Csp2 Stille偶联,用于合成二芳基甲烷和取代的二苯甲酮.
摘要:在这里,我们介绍了在超声催化的巴比尔反应中,在很短的时间内就通过超声斯蒂勒偶合在钯催化下,在一些取代的芳基化合物和苄基三丁基锡化合物之间获得的各种二芳基甲烷的制备方法.以下报道的研究比较了优化通常不稳定的苄基锡衍生物合成的不同方法,这是对涉及苄基-芳基试剂的csp(3)-Csp(2)偶联过程研究的另一贡献.通过某些二芳基甲烷的氧化,可以容易地以非常好的收率制备取代的羧化二苯甲酮.
DOI:10.1016/j.Ultsonch.2012.06.014

专利信息

专利号:WO-9426779-A1
优先权日:1993-05-13
标 题 :PROCESSES AND INTERMEDIATE COMPOUNDS USEFUL FOR THE PREPARATION OF PLATELET GLYCOPROTEIN IIb/IIIa INHIBITORS
发明人：MADUSKUIE THOMAS PETER JR
权利人:DU PONT MERCK PHARMA
摘要:This invention provides processes and intermediates for the synthesis of platelet glycoprotein IIb/IIIa inhibitors of formula (I).

专利号:WO-2024134480-A1
优先权日:2022-12-21
标题:Heterocyclic acrylic acid derivatives as monomers for the synthesis of polymers for use in ion exchange articles
发明人：RASMUSSEN JERALD K; HOCHSTEIN REBECCA A; FISHMAN JOSHUA M; VOLOSHIN ALEXEI M; WATTS ANNABELLE; RICHARDSON KRISTOPHER E; BISHOP LOGAN D C; GRIESGRABER GEORGE W; WLASCHIN KATIE F; COLAK ATAN SEMRA; JULIK EMILY; VAIL ANDREW W
权利人:3M INNOVATIVE PROPERTIES COMPANY
摘要:The present invention relates to monomers of formula (I) having a nitrogen atom that can be protonated at relatively low pH values (e.g., less than pH 9.5 or less than pH 9), polymers containing monomeric units derived from these monomers, anion exchange separation articles having the polymers grafted to a porous substrate, and methods of using the anion separation articles to separate mixtures of materials with different ionic content are described. Advantageously, the anion exchange separation articles can be used to separate biomaterials that cannot be subjected to high pH conditions (e.g., greater than 9 or 9.5) and/or to high ionic strength conditions (e.g., greater than 0.5M or 1M).

专利号:US-2005192265-A1
优先权日:2003-03-20
标 题:Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use of such compounds
发明人：THOMPSON RICHARD C; WILKIE STEPHEN; STACK DOUGLAS R; VANMETER ELDON E; SHI QING; BRITTON THOMAS C; AUDIA JAMES E; REEL JON K; MABRY THOMAS E; DRESSMAN BRUCE A; CWI CYNTHIA L; HENRY STEVEN S; MCDANIEL STACEY L; STUCKY RUSSELL D; PORTER WARREN J
摘要:Disclosed are compounds which inhibit β-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions that include a compound which inhibits β-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.

专利号:US-6849650-B2
优先权日:1998-02-27
标 题:Heterocyclic compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds
发明人：THORSETT EUGENE D; PORTER WARREN J; NISSEN JEFFREY S; LATIMER LEE H; AUDIA JAMES E; DROSTE JAMES
权利人:ATHENA NEUROSCIENCES INC; LILLY CO ELI
摘要:Disclosed are compounds which inhibit β-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits β-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.

专利号:US-6906056-B2
优先权日:1998-06-22
标 题:Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds
发明人：THOMPSON RICHARD C; WILKIE STEPHEN; STACK DOUGLAS R; VANMETER ELDON E; SHI QING; BRITTON THOMAS C; AUDIA JAMES E; REEL JON K; MABRY THOMAS E; DRESSMAN BRUCE A; CWI CYNTHIA L; HENRY STEVEN S; MCDANIEL STACEY L; STUCKY RUSSELL D; PORTER WARREN J
权利人:LILLY CO ELI
摘要:Disclosed are compounds which inhibit β-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions that include a compound which inhibits β-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.

专利号:US-11584772-B2
优先权日:2017-09-12
标 题 :N4-modified cytidine nucleotides and their use
发明人：MESKYS ROLANDAS; JAKUBOVSKA JEVGENIJA; TAURAITE DAIVA
权利人:UNIV VILNIUS
摘要:Disclosed are W-position modified cytidine nucleotides of formula (I). Provided herein are methods of chemical synthesis of AP-modified cytidine nucleoside triphosphates and their applications as well as uses of the cytidine analogues for the synthesis of modified nucleic acids. The nucleic acid molecule includes DNA, RNA or a combination of DNA/RNA. One of many applications of modified cytidine nucleotides described herein is enzyme selection, when an enzyme of interest bears an activity of an esterase, amidase, oxidoreductase, lyase, ligase or other enzymatic activity, formula (I) wherein the substituants are as defined in the appended claims.