CAS: 57105-39-2; N-(3-Indolylacetyl)-L-Alanine

相似化合物

13113-08-1 36838-63-8 1218-34-4

上下游产品

CAS号56-41-7 L-丙氨酸 | CAS号1080025-88-2 1-(1H-benzotria...

📜Methyl (2-(1H-Indol-3-yl)Acetyl)-L-Alaninate置于sodium Hydroxide体系中,用 甲醇 作为反应溶剂,化学反应 1.5H,以97%的收率获得产物n-(3-吲哚乙酰基)-L-丙氨酸
参考文献:合成生长素-氨基酸缀合物的制备
标题:合成生长素-氨基酸缀合物的制备
摘要:摘要 生长素酰胺结合物是最重要的生长素,吲哚-3-乙酸 (Iaa) 的调节剂,Iaa 被认为负责植物内的许多重要过程.在此,Iaa 的酰胺缀合物在 1-羟基苯并三唑的存在下,采用一种简单有效的偶联方法与 Wsci.hcl(一种水溶性缩合剂)合成.具有 10 个氨基酸的 Iaa 缀合物及其相应的甲酯以优异的产率制备,高达 95%,旨在促进它们在植物物种中的鉴定.八种 Iaa-氨基酸甲酯结合物首次在此得到表征.图形概要
DOI:10.1080/00397911.2019.1605446

专利信息

专利号:US-9217012-B2
优先权日:2009-04-08
标题 :Inhibitors of protein tyrosine phosphatases
发明人：ZHANG ZHONG-YIN; ZHANG SHENG
权利人:ZHANG ZHONG-YIN; ZHANG SHENG; UNIV INDIANA RES & TECH CORP
摘要:Disclosed herein are compounds that selectively inhibit members of the PTP family of enzymes. Synthesized compounds demonstrated selective inhibition of TC-PTP. Also provided are methods of using the compounds and formulations containing the compounds. Also described is a fluorescence-tagged combinatorial library synthesis and screening method. And methods of using these compounds to effect enzyme activity both in cells and in vitro as well as method of using these compounds to treat diseases in human and animals.

专利号:WO-2016181414-A1
优先权日:2015-05-12
标题:Process for the synthesis of ivacaftor and related compounds