CAS: 54549-27-8; (3R,4S,5S,6R)-2-(Hexadecyloxy)-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-3,4,5-Triol

该化合物是一种非离子表面活性剂和烷基甘基丁衍生物,由于生物降解性较轻,在生物化学和制药应用中广泛使用,其闪光性结构以流体生物甘油为主和缺水的六十二基链为主,使薄膜蛋白有效溶解,同时保持蛋白稳定性;该复合物显示出低临界小鼠浓度,提高了其在蛋白提取和晶化的洗涤剂中的用途;其生物相容性和最小的密度效应使其适合敏感的生物系统;此外,六十二基D-甘蓝表面在生理条件下表现出高度的化学稳定性,支持其在药物交付和化妆制剂中的使用.

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CAS号2280-44-6 D-glucopyranose | CAS号36653-82-4 十六醇 | CAS号572-09-8 2,3,4,6-四乙酰氧基-a...

合成工艺路线路线简述

  • 合成目标产物 Hexadecyl D-Glucoside 主要起始原料 D-Glucose And 1-Hexadecanol
  • (文献来源)合成步骤主要原料 D-Glucose 和 1-Hexadecanol
📜Peracetylated 1-O-Palmityl-D-Glucose置于sodium Methylate体系中,化学反应生成 十六烷基-D-葡萄糖苷
参考文献:Namba,Yukihiro; Sakakibara,Toshiyuki; Masada,Mikio,Chemistry Letters,1989,P. 2145-2148
标题:Namba,Yukihiro; Sakakibara,Toshiyuki; Masada,Mikio,Chemistry Letters,1989,P. 2145-2148

海关参考信息

专利信息


专利号:EP-1493431-B1
优先权日:2003-07-03
标题:Use of an extract of bauhinia for the preparation of pharmaceutical and cosmetic compositions
发明人:WIRTH CORINNA DR; BUCHHOLZ HERWIG DR
权利人:MERCK PATENT GMBH
摘要:Use of an aqueous or aqueous-alcoholic extract (A) of Bauhinia is claimed to make a composition for cosmetic or pharmaceutical treatment of skin and hair. Use of an aqueous or aqueous-alcoholic extract (A) of Bauhinia is claimed to make a composition for: (a) care, preservation or improvement of the general condition of the skin or hair; (b) prevention and/or inhibition of the aging process for human skin or hair; (c) for promoting healing of wounds; (d) for prevention and/or treatment of skin diseases associated with abnormal keratinization, and (e) for prevention and/or treatment of all malignant or benign growths of the dermis or epidermis. An independent claim is also included for a composition containing (A). ACTIVITY : Dermatological; Vulnerary; Antiseborrheic; Antipsoriatic; Cytostatic; Antiinflammatory; Virucide. MECHANISM OF ACTION : Protein glycosylation inhibitor. In a test, human fibroblasts were cultured in the presence of Vitamin C to stimulate collagen synthesis, then lysed and labeled with tritiated glucose for 15 days, Proteins were removed, extraction and precipitation were carried and the amount of bound glucose measured by liquid scintillation counting. Addition of an aqueous-alcoholic extract of Bauhinia fortificata (0.03 mg/ml), reduced protein glycosylation to 55% of that in a control.

专利号:EP-0437460-B1
优先权日:1988-10-05
标 题 :Process for directly producing alkylglycosides
发明人:HILL KARLHEINZ DR; WUEST WILLI DR; WOLLMANN JOSEF; BIERMANN MANFRED DR; ROSSMAIER HENRY DR; ESKUCHEN RAINER DR; BRUNS ANDREAS DR; HELLMANN GUENTER DR; OTT KARL-HEINZ DR; WINKLE WALTER DR; WOLLMANN KLAUS DR
权利人:HENKEL KGAA
摘要:The aliphatic primary alcohols are made to react with a glycose, in particular glucose, in the presence of an acid catalyst according to a process following given steps in such a manner that, in improved direct synthesis and after a subsequent necessary bleaching stage, particularly light-coloured and alkali-fast alkylglycosides are obtained. Said process can be carried out at laboratory level as well as on an industrial production scale.

专利号:CN-1062734-A
优先权日:1991-12-06
标题 :The direct synthesis technique of alkyl glucoside

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