CAS: 531-72-6; Thiacetarsamide
该化合物是复杂的有机化合物,其结构中含砷和硫磺,其特征是独特的功能组,包括氨化物和硫醚,有助于其反应和在医学化学和材料科学等各个领域的潜在应用.氨基碳基化合物组的存在表明氢与生物系统结合和互动的潜力,而硫酸联系可能具有特定的电子特性.此外,乙酸混合物可影响水环境中的溶性与再活动.
- 英文名称Thiacetarsamide
- 中文名称4-[二(羧基甲硫基)胂基]苯甲酰胺
- IUPAC名称2,2'-(((4-carbamoylphenyl)arsanediyl)bis(sulfanediyl))diacetic acid
- 其它别名Aceticacid, mercapto-, diester with p-carbamoyldithiobenzenearsonous acid (6CI,7CI); Acetic acid, mercapto-, p-carbamoyldithiobenzenearsonite (21) (8CI); (p-Carbamoylphenylarsylenedithio)diacetic acid; (p-Carbamylphenylarsylenedithio)diacetic acid; Arsenamide; Bis[carboxymethylmercapto](p-carbamylphenyl)arsine; Caparside; Thiacetarsamide; Thioacetaramide; p-[Bis(carboxymethylmercapto)arsino]benzamide
- CAS编号531-72-6
- MFCD编号:MFCD00864549
- FDA UNII编号:VMF4ELY9TZ
- 分子式:C11H12AsNO5S2分子量:377.27
- 产品CID: 1517036
- 同类组份化合物CAS531-72-6 (free base)7681-85-8 (sodium)4433-82-0 (sodium)
- 产品分类有机原料 → 苯类化合物 → 苯和取代衍生物
物理性质
MSDS等安全信息
合成工艺路线路线简述
📜巯基乙酸,Alkaline Earth Salt Of/the/ Methylsulfuric Acid置于水体系中,化学反应生成 4-[二(羧基甲硫基)胂基]苯甲酰胺
参考文献:Lxxxix.-锥虫作用和化学成分.第九部分 含酰胺基的芳香酸
标题:Lxxxix.-锥虫作用和化学成分.第九部分 含酰胺基的芳香酸
摘要:
DOI:10.1039/jr9300000669
海关参考信息
- 2912110000-甲醛
2912120000-乙醛
2912210000-苯甲醛
2915110000-甲酸 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
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供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
1: Bowman DD, Drake J. Examination of the "susceptibility gap" in the treatment of canine heartworm infection. Parasit Vectors. 2017 Nov 9;10(Suppl 2):513. doi: 10.1186/s13071-017-2433-9. Review.
2: Keller NS, Stefánsson A, Sigfússon B. Determination of arsenic speciation in sulfidic waters by Ion Chromatography Hydride-Generation Atomic Fluorescence Spectrometry (IC-HG-AFS). Talanta. 2014 Oct;128:466-72. doi: 10.1016/j.talanta.2014.04.035. Epub 2014 Apr 30. Russian. doi: 10.1021/ac1024717. Epub 2010 Nov 29. doi: 10.1053/j.gastro.2008.01.035. Epub 2008 Jan 18.
7: Ellis JL, Conklin SD, Gallawa CM, Kubachka KM, Young AR, Creed PA, Caruso JA, Creed JT. Complementary molecular and elemental detection of speciated thioarsenicals using ESI-MS in combination with a xenon-based collision-cell ICP-MS with application to fortified NIST freeze-dried urine. Anal Bioanal Chem. 2008 Apr;390(7):1731-7. Epub 2007 Dec 23. Epub 2007 Sep 25. Epub 2006 Apr 27.
合成参考文献
摘要:T3: Emsley, John (2001). Nature's Building Blocks: An A-Z Guide to the Elements. Oxford: Oxford University Press.
摘要:L20: Wikipedia. Arsenic toxicity. Last Updated 22 February 2009.
摘要:A17: Kitchin KT, Wallace K: The role of protein binding of trivalent arsenicals in arsenic carcinogenesis and toxicity. J Inorg Biochem. 2008 Mar;102(3):532-9. doi: 10.1016/j.jinorgbio.2007.10.021. Epub 2007 Nov 22.
摘要:Raynaud JP. Thiacetarsamide (adulticide) versus melarsomine (RM 340) developed as macrofilaricide (adulticide and larvicide) to cure canine heartworm infection in dogs. Ann Rech Vet. 1992;23(1):1–25.
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