CAS: 430-50-2; 1-Fluoropropan-2-Ol

该化合物是一个有机化合物,其特征是含有一种附于丙醇链第二个碳的氟原子,其分子式为C3H7F,表明这是一种简单的酒精,具有氟化替代物,该化合物通常是一种无色液体,具有一种特质的气味,在水中溶解,具有中等的挥发性;氟原子的存在可影响其化学反应和物理特性,例如沸点和极度,与非氟化酒精相比.2-丙醇,1-氟-经常用于各种用途,包括作为化学反应中的溶剂和其他氟化化合物的合成.在处理该物质时,安全考虑十分重要,因为吸入或摄入该物质可能会对健康造成危害,而且应当采取适当的预防措施,以尽量减少接触.

结构式图片

欧盟法规

ECHA物质C&L通报

上下游产品

CAS号430-51-3 氟代丙酮 | CAS号503-09-3 环氧氟丙烷 | CAS号127-00-4 1-氯-2-丙醇 | CAS号5689-83-8 4-甲基-1,3,2-二氧硫杂... | CAS号75-56-9 环氧丙烷 | CAS号430-51-3 氟代丙酮 | CAS号70628-05-6 1-fluoropropan-...

合成工艺路线路线简述

  • 合成目标产物 1-Fluoro-2-Propanol 主要起始原料 Fluoroacetone
  • (文献来源)合成步骤主要原料 Fluoroacetone
📜环氧氟丙烷置于lithium Aluminium Tetrahydride体系中,用 乙醚 作为反应溶剂,化学反应生成 1-氟丙烷-2-醇
参考文献:Use Of Substituent Effects On Isotope Effects To Distinguish Between Proton And Hydride Transfers. Part I. Mechanism Of Oxidation Of Alcohols By Bromine In Water1-3
标题:Use Of Substituent Effects On Isotope Effects To Distinguish Between Proton And Hydride Transfers. Part I. Mechanism Of Oxidation Of Alcohols By Bromine In Water1-3
摘要:
DOI:10.1021/ja01469A039

海关参考信息

专利信息


专利号:WO-8911470-A1
优先权日:1988-05-27
标题 :Dihalogeno-3,3 fluoro-2 propenols-1, preparation method and utilization for the synthesis of fluoro-2 acrylic and dihalogeno-3,3 fluoro-2 acrylic acids and their derivatives
发明人:WAKSELMAN CLAUDE; NGUYEN THOAI; MOLINES HUGUETTE
权利人:CENTRE NAT RECH SCIENT
摘要:The invention relates to dihalogeno-3,3 fluoro-2 propenol-1 having the formula X?1X?2C=CF-CH2?OH (I), wherein X?1 and X?2, which may be identical or different, represent a fluorine, a chlorine or a bromine atom providing that X?1 and X?2 do not represent both a chlorine atom. These compounds may be prepared by reaction of an alcohol having the formula HCH?1X?2-CFX?3-CH2?OH (II), X?1 and X?2 have the meaning given hereabove and X?3 is a fluorine, chlorine or bromine atom, similar to or different from X?1 and/or X?2, with an organolithian compound. They may be used to prepare halides of the fluoro-2 acrylic acid and of the dihalogeno-3,3 fluoro-2 acrylic acids or their esters.

专利号:EP-0042408-A1
优先权日:1979-12-26
标 题 :METHODS OF SYNTHESIS OF HEXAFLUOROISOPROPANOL FROM IMPURE MIXTURES AND SYNTHESIS OF A FLUOROMETHYL ETHER.

专利号:WO-8101843-A1
优先权日:1979-12-26
标 题 :Methods of synthesizing hexafluoroisopropanol from impure mixtures and synthesis of a fluoromethyl ether therefrom

专利号:US-8252778-B2
优先权日:2006-03-24
标题:Highly fluorinated oils and surfactants and methods of making and using same
发明人:YU YIHUA; JIANG ZHONG-XING
权利人:YU YIHUA; JIANG ZHONG-XING; UNIV UTAH RES FOUND
摘要:Disclosed are compounds comprising the structure: n nIn one aspect, the compounds exhibit maximum symmetric branching. Also disclosed are bilayers, micelles, coatings, and nanoparticles comprising the disclosed compounds. Also disclosed are processes for the preparation of the disclosed compounds and methods of using the disclosed compounds. Also disclosed are highly fluorinated dendrons and methods for making same. Also disclosed are methods for Fluorous Mixture Synthesis and tagging. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

专利号:JP-2004520449-A
优先权日:2001-06-05
标题 :Process for removing dimethyl ether in the synthesis of sevoflurane

专利号:JP-4162590-B2
优先权日:2001-06-05
标 题 :Process for removing dimethyl ether in the synthesis of sevoflurane

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✅ COA系统入驻 | 共享模式

合成参考文献


摘要:Journal of Industrial Hygiene and Toxicology., 31(60), 1949
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