CAS: 3142-66-3; 3-Hydroxypentan-2-One

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📜2,3-戊二酮 反应生成 3-羟基-2-戊酮
参考文献:Higasi; Maruyama,Rikagaku Kenkyusho Iho,Vol. 1,P. 92
标题:Higasi; Maruyama,Rikagaku Kenkyusho Iho,Vol. 1,P. 92

专利信息

专利号:US-8535689-B2
优先权日:2007-10-01
标题 :Identification of bacterial autoinducer and use in treating bacterial pathogenicity
发明人：BASSLER BONNIE; SEMMELHACK MARTIN; HIGGINS DOUGLAS A; BOLITHO MEGAN EILEEN; KRAML KRISTINA M; NG WAI-LEUNG
权利人:BASSLER BONNIE; SEMMELHACK MARTIN; HIGGINS DOUGLAS A; BOLITHO MEGAN EILEEN; KRAML KRISTINA M; NG WAI-LEUNG; UNIV PRINCETON
摘要:A bacterial autoinducer, CAI-1, was purified and its structure identified. Methods for synthesis of the autoinducer and its analogues were elucidated. Methods of using the autoinducer or its analogues for treating bacterial pathogenicity and bio film formation are described. Methods for prevention and treatment of cholera are described. Synthetic (S)-3-hydroxytridecan-4-one functions as well as natural CAI-1 in repressing production of the virulence factor toxin co-regulated pilus (TCP). Strategies are described to manipulate bacterial quorum sensing in the clinical arena.

专利号:US-2004053999-A1
优先权日:1997-09-17
标题 :Novel compounds and methods for synthesis and therapy
发明人：BISCHOFBERGER NORBERT W; DAHL TERRENCE C; HITCHCOCK MICHAEL J M; KIM CHOUNG U; LEW WILLARD; LIU HONGTAO; MILLS ROGER G; WILLIAMS MATTHEW A
摘要:Novel compounds are described. The compounds generally comprise an acidic group, a basic group, a substituted amino or N-acyl and a group having an optionally hydroxylated alkane moiety. Pharmaceutical compositions comprising the inhibitors of the invention are also described. Methods of inhibiting neuraminidase in samples suspected of containing neuraminidase are also described. Antigenic materials, polymers, antibodies, conjugates of the compounds of the invention with labels, and assay methods for detecting neuraminidase activity are also described.

专利号:US-6225341-B1
优先权日:1995-02-27
标 题:Compounds and methods for synthesis and therapy
发明人：BISCHOFBERGER NORBERT W; KIM CHOUNG U; LEW WILLARD; LIU HONGTAO; WILLIAMS MATTHEW A
权利人:GILEAD SCIENCES INC
摘要:Novel compounds are described. The compounds generally comprise an acidic group, a basic group, a substituted amino or N-acyl and a group having an optionally hydroxylated alkane moiety. Pharmaceutical compositions comprising the inhibitors of the invention are also described. Methods of inhibiting neuraminidase in samples suspected of containing neuraminidase are also described. Antigenic materials, polymers, antibodies, conjugates of the compounds of the invention with labels, and assay methods for detecting neuraminidase activity are also described.

专利号:US-2011269201-A1
优先权日:2010-04-30
标题:Redirected bioenergetics in recombinant cellulolytic clostridium microorganisms
发明人：GRAY KEVIN; O'MULLAN PATRICK
权利人:QTEROS INC
摘要:Compositions and methods are provided for redirecting metabolic solventogenesis pathways to enhance the product yield from fermentation of biomass. Clostridium microorganism pathways are modified to extend the growth phase and prevent inhibition of acetaldehyde while bypassing the synthesis of acetyl CoA.

专利号:CN-110523400-A
优先权日:2018-05-25
标 题:Synthesis of silica gel chromatography packing by microemulsion method

专利号:EP-3305900-B1
优先权日:2005-12-01
标题:Enzymatic encoding methods for efficient synthesis of large libraries