CAS: 19179-31-8; 3,5-Dimethoxybenzonitrile

上下游产品

CAS号7311-34-4 3.5-二甲氧基苯甲醛 | CAS号557-21-1 氰化锌 | CAS号68-12-2 N,N-二甲基甲酰胺 | CAS号7677-24-9 三甲基氰硅烷 | CAS号192182-54-0 3,5-二甲氧基苯硼酸 | CAS号55305-43-6 N-氰基-4-甲基-N-苯基苯磺酰胺 | CAS号20469-65-2 1-溴-3,5-二甲氧基苯 | CAS号365564-07-4 3,5-二甲氧基苯基硼酸频那醇酯 | CAS号34967-24-3 3,5-二甲氧基苄胺 | CAS号215649-02-8 5-(6-bromo-2-me... | CAS号22168-70-3 cyclohexyl-(3,5... | CAS号26130-49-4 3,5-二甲氧基苯甲脒 | CAS号151-10-0 间苯二甲醚 | CAS号19179-36-3 3,5-二羟基苯甲腈 | CAS号17213-58-0 3,5-二甲氧基苯甲酰胺 | CAS号116496-27-6 (3,4-dimethoxyp... | CAS号453566-08-0 N'-羟基-3,5-二甲氧基苯羧酰亚胺 | CAS号58545-33-8 1,3-dimethoxy-5...

3,5-二甲氧基苯甲醛置于lithium Cyanide,叠氮化四丁基铵体系中,用 四氢呋喃,甲苯 用作溶剂,化学反应 2.5H,反应生成3,5-二甲氧基苯腈
参考文献:无需一碳同系化通过氰磷酸酯将苯甲醛转化为苯甲腈
标题:无需一碳同系化通过氰磷酸酯将苯甲醛转化为苯甲腈
摘要:研究发现,通过氰基磷酸盐 (Cp) 与叠氮化四丁基铵 (Bu4N.n3) 将苯甲醛转化为苯甲腈,可以以中等到高产率提供一系列苯甲腈.由于苯甲腈的cn-碳源自苯甲醛的甲酰基-碳,这是一种新型的cp-反应,与过去的单碳腈同系化反应明显不同.相反,酮-或脂肪醛-Cp与bu4N.n3的反应导致单脱乙基化形成四丁基铵盐.
Doi:10.1055/a-2283-6798

专利信息

专利号:US-7253324-B1
优先权日:2007-01-23
标 题:Process for the synthesis of biologically active oxygenated compounds by dealkylation of the corresponding alkylethers
发明人：MAJEED MUHAMMED; THOMAS SAMUEL MANOHARAN; NAGABHUSHANAM KALYANAM; BALAKRISHNAN SIVAPRAKASH KURUM; PRAKASH SUBBALAKSHMI
权利人:SAMI LABS LTD
摘要:Alkoxy aromatic compounds are conveniently dealkylated to the corresponding phenolic compounds by treatment with aluminum chloride/N,N-dimethyl aniline complex. Aromatic poly O-demethylation is a unique feature of this invention. This process is applicable to the manufacture of polyphenols such as Resveratrol, Oxyresveratrol, Gnetol.

专利号:US-10508092-B2
优先权日:2016-09-02
标题 :Synthesis of novel analogs of diptoindonesin G, compounds formed thereby, and pharmaceutical compositions containing them
发明人：XU WEI; TANG WEIPING; LIU JITIAN; KOLESAR JILL
权利人:WISCONSIN ALUMNI RES FOUND
摘要:Disclosed are unnatural analogs of Diptoindonesin G, methods to make the analogs, pharmaceutical compositions containing the analogs, and methods of using the analogs to inhibit neoplastic cell growth.

专利号:US-6380436-B1
优先权日:1998-05-12
标 题 :Process for the synthesis of alkoxyalkyl (trifluormethylphenyl) methanones
发明人：THENNATI RAJAMANNAR; DEO KESHAV; MIDHA AJAY SOHANLAL; CHANDRA TILAK; PATEL VIJAY MULJIHHAI
权利人:SUN PHARMACEUTICAL IND LTD
摘要:A new process is described for the preparation of (alkoxyalkyl)(4-trifluoromethylphenyl)methanones. The process comprises reacting a 4-trifluoromethylbenzonitrile with an alkoxyalkyl Grignard in the presence of a suitable polar aprotic solvent. The compound (4-methoxybutyl)(4-trifluoromethylphenyl)methanone is useful as an intermediate in the preparation of the antidepressant drug fluvoxamine.

专利号:US-2018065945-A1
优先权日:2016-09-02
标 题 :Synthesis of novel analogs of diptoindonesin g, compounds formed thereby, and pharmaceutical compositions containing them

专利号:US-9273081-B2
优先权日:2010-03-24
标 题:Method for in-situ formation of metathesis catalysts
发明人：SCHRODI YANN
权利人:SCHRODI YANN
摘要:Synthetic methods for the in-situ formation of olefin metathesis catalysts are disclosed, as well as the use of such catalysts in metathesis reactions of olefins and olefin compounds. In one aspect, a method is provided for synthesizing an organometallic compound of the formula n ncomprising contacting a precursor compound of the formula (X 1 X 2 ML j L 1 k L 3 m ) i with an acetylenic compound comprising a chelating moiety, optionally, in the presence of a neutral electron donor, wherein M is a Group 8 transition metal, L, L 1 , L 2 , and L 3 are neutral electron donors, X 1 and X 2 are anionic ligands, j is 1, 2, or 3; k is zero, 1, or 2; m is zero or 1; n is 1 or 2; and i is an integer; with the proviso that k is zero when the precursor compound is contacted with the acetylenic compound in the presence of the neutral electron donor, and R 1 and R 2 are independently selected from hydrocarbyl, substituted hydrocarbyl, heteroatom-containing hydrocarbyl, substituted heteroatom-containing hydrocarbyl, and functional groups, wherein R 1 and R 2 are linked and together form one or more cyclic groups, R 2 and L 2 are linked and together form one or more cyclic groups, and any other two or more of X 1 , X 2 , L 1 , L 2 , L 3 , R 1 , and R 2 can be taken together to form one or more cyclic groups. The invention has utility in the fields of catalysis, organic synthesis, polymer chemistry, and industrial and fine chemicals chemistry.

专利号:US-7569606-B2
优先权日:2006-01-26
标 题 :Platinum complexes with mononitrile-containing ligands
发明人：XIAO ZEJUN; HAUSHEER FREDERICK H; PETLURU PAVANKUMAR
权利人:BIONUMERIK PHARMACEUTICALS INC
摘要:Disclosed herein are novel platinum-based complexes possessing one nitrile substituent group (mononitrile) covalently-bonded to the platinum, one or more nitrogen donor ligands capable of forming hydrogen bonds with the bases in DNA or RNA and leaving groups (i.e., L 1 and L 2 )which can be hydrolyzed iii vivo to active species, which can then form coordinate adducts with DNA or RNA at the Guanine or Adenine bases thereof. Also disclosed herein are the reaction schemes for the synthesis of said platinum complexes, as well as methods of treatment of various types of cancer by the administration of a pharmaceutically-effective dose of said novel platinum complexes.