CAS: 18549-40-1; (R)-1-((3Ar,5R,6S,6Ar)-6-Hydroxy-2,2-Dimethyltetrahydrofuro[2,3-D][1,3]Dioxol-5-yl)Ethane-1,2-Diol

上下游产品

CAS号582-52-5 双丙酮葡萄糖 | CAS号33737-08-5 1,2-O-isopropyl... | CAS号29364-56-5 1-O,2-O-Isoprop... | CAS号7284-07-3 a-D-xylo-Hex-5-... | CAS号753488-63-0 1,2:5,6-di-O-is... | CAS号18006-25-2 1,2-O-(1-甲基乙亚基)... | CAS号1824-88-0 .alpha.-D-Gluco... | CAS号709-50-2 甲基β-D-吡喃葡萄糖苷半水合物 | CAS号97-30-3 甲基葡萄糖苷 | CAS号19130-96-2 1-脱氧野尻霉素 | CAS号2875-90-3 a-D-Glucofurano... | CAS号253328-56-2 1,2-O-Isopropyl... | CAS号2816-87-7 a-D-Glucofurano... | CAS号2946-02-3 [7,7-dimethyl-3...

双丙酮葡萄糖置于ytterbium(III) Triflate体系中,用 乙腈 用作溶剂,化学反应 3.0H,以88%的收率获得1,2-O-异亚丙基-D-呋喃葡萄糖
参考文献:Yb(Otf)3.h2O:一种用于化学选择性水解异亚丙基缩醛的新型试剂
标题:Yb(Otf)3.h2O:一种用于化学选择性水解异亚丙基缩醛的新型试剂
摘要:在环境温度下,使用催化量的 Yb(Otf)3.h2O 在乙腈中实现了末端异亚丙基缩醛的简便化学选择性水解.
Doi:10.1246/cl.2001.430

专利信息

专利号:US-2024409571-A1
优先权日:2023-06-08
标 题:Chemoenzymatic synthesis of n-acetylated gangliosides and glycosphingosines
发明人：CHEN XI; YU HAI; MISHRA BIJOYANANDA; ZHENG ZIMIN; AGRAHARI ANAND KUMAR; GUCCHAIT ARIN
权利人:UNIV CALIFORNIA
摘要:Described herein are novel stable 9-N-, 8-N-, and 7-N-acetyl analogues of instable 9-O-acetyl, 8-O-acetyl, and 7-O-acetyl b-series gangliosides and glycosphingosines, including GD3, GD2, GD1b, GT1b, GQ1b, and their glycosphingosines. Chemoenzymatic methods for the production of the stable 9-N-, 8-N-, and 7-N-acetyl analogues are also described herein.

专利号:US-9867899-B2
优先权日:2010-05-24
标题 :Reinforced adhesive complex coacervates and methods of making and using thereof
发明人：STEWART RUSSELL J
权利人:UNIV UTAH RES FOUND
摘要:Described herein is the synthesis of reinforced adhesive complex coacervates and their use thereof. The reinforced adhesive complex coacervates are composed of (a) at least one polycation, (b) at least one polyanion, and (c) a reinforcing component. The adhesive complex coacervates described herein can be subsequently cured to produce strong, cohesive adhesives. The reinforced adhesive complex coacervates have several desirable features when compared to conventional adhesives. The reinforced adhesive complex coacervates are effective in wet or underwater applications. The reinforced adhesive complex coacervates described herein, being phase separated from water, can be applied underwater without dissolving or dispersing into the water. The reinforced adhesive complex coacervates have numerous biological applications as bioadhesives and bioactive delivery devices. In particular, the reinforced adhesive complex coacervates described herein are particularly useful in underwater applications and situations where water is present such as, for example, wet tissues in physiological conditions.

专利号:US-9913926-B2
优先权日:2008-01-24
标题 :Adhesive complex coacervates and method of making and using thereof
发明人：STEWART RUSSELL J; SHAO HUI
权利人:STEWART RUSSELL J; SHAO HUI; UNIV UTAH RES FOUND
摘要:Described herein is the synthesis of adhesive complex coacervates and their use thereof. The adhesive complex coacervates are composed of a mixture of one or more polycations and one or more polyanions. The polycations and polyanions in the adhesive complex coacervate are crosslinked with one another by covalent bonds upon curing. The adhesive complex coacervates have several desirable features when compared to conventional bioadhesives, which are effective in water-based applications. The adhesive complex coacervates described herein exhibit good interfacial tension in water when applied to a substrate (i.e., they spread over the interface rather than being beaded up). Additionally, the ability of the complex coacervate to crosslink intermolecularly increases the cohesive strength of the adhesive complex coacervate. They have numerous biological applications as bioadhesives and drug delivery devices and are particularly useful in underwater applications and situations where water is present such as, for example, physiological conditions.

专利号:US-3699103-A
优先权日:1970-10-07
标 题 :Process for the manufacture of 5-desoxy-l-arabinose and novel intermediates
发明人：KISS JOSEPH
权利人:HOFFMANN LA ROCHE
摘要:A MULTI-STEP, STEREO-SPECIFIC SYNTHESIS OF 5-DESOXY-LARABINOSE FROM THE READILY AVAILABLE AND INEXPENSIVE STARTING MATERIALS D-GLUCOSE OR D-XYLOSE IS DISCLOSED. 5-DESOXYL-ARABINOSE IS A KNOWN BUILDING BLOCK FOR THE MANUFACTURE OF BIPTERIN, A NATURALLY OCCURING MATERIAL HAVING USES AS A GROWTH FACTOR, AND ANTIOXIDANT, AND AS A PRECURSOR FOR CO-FACTORS OF ENZYMES LEADING TO THE PRODUCTION OF VALUABLE AMINO ACIDS SUCH AS PHENYLALANINE, TRYPTOPHAN AND L-DOPA. L-DOPA IS A VALUABLE MEDICAMENT WHICH HAS RECENTLY BEEN LICENSED IN THIS COUNTRY FOR USE IN THE TREATMENT OF PARKINSON''S DISEASE.

专利号:US-9999700-B1
优先权日:2010-11-12
标 题 :Simple coacervates and methods of use thereof
发明人：STEWART RUSSELL J
权利人:UNIV UTAH RES FOUND
摘要:Described herein is the synthesis of adhesive from simple adhesive coacervates and their uses thereof. The adhesives are composed of (a) a polyanion in the absence of a polycation, wherein the polyanion comprises at least one crosslinking group capable of covalently crosslinking with itself, and (b) a sufficient amount of a complimentary multivalent cation or multivalent anion to produce the simple coacervate. The adhesives have numerous medical and non-medical applications.

专利号:US-5344924-A
优先权日:1991-02-20
标 题 :Solvent-free synthesis of ethereally substituted blocked monosaccharides and the selective hydrolysis thereof
发明人：ARORA SUDERSHAN K
权利人:GREENWICH PHARMA
摘要:A solvent-free method for synthesizing an ethereally-substituted, blocked monosaccharide comprising the steps of: n 1) mixing, in the absence of solvent, a partially blocked monosaccharide unblocked at one position, an alkyl halide or a substituted alkyl halide, and an anhydrous alkali base; n 2) heating the mixture to a temperature sufficient to allow the mixture to react; n 3) maintaining the mixture at a suitable temperature for a time sufficient to form an ethereally-substituted blocked monosaccharide and drive off any water produced; n 4) removing any unreacted alkyl halide or substituted alkyl halide from the mixture; n 5) recovering the ethereally-substituted blocked monosaccharide product from the mixture; and, optionally, n 6) selectively hydrolyzing the ethereally-substituted blocked monosaccharide product to remove one or more of the acetal blocking groups.