CAS: 1119-72-8; (2Z,4Z)-Hexa-2,4-Dienedioic Acid

该化合物是一种含有分子式C6H6O4的二恶英二恶英酸,其结构具有两个相交的双重结合体,该化合物在有机合成和工业应用中起着宝贵的中间作用,特别是在生产乙酸等生物聚合物(尼龙的前体)方面,其硬性,平面结构和再活性使其适合催化转化和可持续材料开发.此外,Cis,cis-muconicy酸可以通过微生物发酵,与绿色化学原则保持一致,从可再生原料中衍生出,其高纯度和稳定性在受控制的条件下确保研究和工业过程的一贯性能.

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相似化合物

3588-17-8 110-16-7 110-17-8

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CAS号120-80-9 邻苯二酚 | CAS号79-21-0 过氧乙酸 | CAS号108-95-2 苯酚 | CAS号2280-44-6 D-glucopyranose | CAS号583-63-1 2-苯醌 | CAS号61186-96-7 2,4-HEXADIENEDI... | CAS号64330-65-0 (2Z,4Z)-hexa-2,... | CAS号90-02-8 水杨醛 | CAS号69-72-7 水杨酸 | CAS号3588-17-8 反式,反式-1,3-丁二烯-1... | CAS号94-60-0 1,4-环己烷二羧酸二甲酯 | CAS号6666-46-2 muconolactone | CAS号18749-86-5 (2Z)-2-(5-oxoox... | CAS号629-11-8 1,6-己二醇 | CAS号124-04-9 己二酸 | CAS号87080-01-1 hex-2c-enedioic acid | CAS号29311-53-3 3-Hexenedioic a... | CAS号105-60-2 己内酰胺 | CAS号124-09-4 1,6-己二胺

合成工艺路线路线简述

    📜A-无水葡萄糖酯置于大观霉素,莽草酸,氯霉素,氨苄西林,异丙基-Beta-D-硫代半乳糖吡喃糖苷,Sodium Hydroxide体系中,化学反应生成顺,顺-已二烯二酸
    参考文献:Methods For Producing Isomers Of Muconic Acid And Muconate Salts
    标题:Methods For Producing Isomers Of Muconic Acid And Muconate Salts
    摘要:通过提供从可再生碳源通过生物催化转化产生的顺式,反式-顺式,反式异构体的顺丁二烯二酸的方法;在反应条件下将顺式,顺式-顺丁二烯二酸异构化为顺式,反式-顺丁二烯二酸;分离顺式,反式-顺丁二烯二酸;并结晶顺式,反式-顺丁二烯二酸.顺式,反式异构体可以进一步异构为反式,反式异构体.在一个例子中,该方法包括培养表达3-脱氢植酸脱水酶,原儿茶酸脱羧酶和邻苯二酚1,2-双加氧酶的重组细胞,在包含可再生碳源的培养基中,并在可再生碳源被细胞芳香族氨基酸生物合成的共同途径中的酶将可再生碳源转化为3-脱氢植酸的条件下,将3-脱氢植酸生物催化转化为顺式,顺式-顺丁二烯二酸.

    海关参考信息

    专利信息


    专利号:US-12344881-B2
    优先权日:2023-09-27
    标题 :Genetic engineering bacterium for de novo synthesis of cis,cis-muconic acid by taking glucose as substrate and applications thereof
    发明人:TAN TIANWEI; LI MENGLEI
    权利人:UNIV BEIJING CHEM TECH
    摘要:The present invention discloses a genetic engineering bacterium for de novo synthesis of cis,cis-muconic acid by taking glucose as a substrate and applications thereof, and belongs to the technical field of genetic recombination and metabolic engineering. The genetic engineering bacterium for de novo synthesis of cis,cis-muconic acid (MA) by taking glucose as the substrate disclosed in the present invention is modified with chassis microbes, and includes recombinant Corynebacterium glutamicum for a cis,cis-muconic acid pathway construction module and an intermediate high-yield module. Production capacity of strains is greatly improved; MA of 90.2 g/L is finally obtained in fermentation liquor; and possibilities are provided for green and low-cost production of numerous chemicals such as adipic acid and nylon-66.

    专利号:US-12263464-B2
    优先权日:2018-03-14
    标题 :Method for in-situ synthesis of metal organic frameworks (MOFs), covalent organic frameworks (COFs) and zeolite imidazolate frameworks (ZIFs), and applications thereof
    发明人:PAHWA DEEPAK; PAHWA VARUN; CHOUDHARY ANIL KUMAR; SONIA; JHA VIVEK KUMAR; CHAUHAN ANJALI; YADAV ANNU
    权利人:DESICCANT ROTORS INTERNATIONAL PRIVATE LTD
    摘要:The present invention relates to a method for the in situ synthesis of of MOFs (metal organic frameworks), COFs (covalent organic frameworks), and ZIFs (Zeolitic imidazolate framework), onto and within different types of porous substrates, and their applications. The present invention provides a unique and easy to utilize method by which a number of MOFs, COFs and ZIFs can be synthesized directly onto and within a porous substrate with high performance efficiency ensuring higher grammage in formation of adsorbent product onto and within the substrate.

    专利号:US-2022089618-A1
    优先权日:2019-01-29
    标题:Solid-State Synthesis Of Precursors Of Metal-Organic Frameworks
    发明人:MAJANO GERARDO J; FALKOWSKI JOSEPH M
    权利人:EXXONMOBIL RES & ENG CO
    摘要:Metal-organic frameworks (MOFs) are highly porous entities comprising a multidentate ligand coordinated to multiple metal atoms, typically as a coordination polymer. MOFs are usually produced from a solvent in powder form under hydrothermal or solvothermal synthesis conditions. Alternately, powder-form precursors of MOFs may be formed by milling or mulling a substantially solid mixture of a metal salt and a multidentate organic ligand, optionally in the presence of a small amount of a solvent. The powder-form precursors may then undergo heating, typically in the absence of applied shear, to produce the corresponding MOF. Mulling may be differentiated from milling at least in that mulling applies to the substantially solid mixture at a non-constant pressure and milling applies a constant pressure while forming the powder-form precursor. In some cases, mulling may promote more effective formation of the powder-form precursor compared to milling.

    专利号:US-2024208900-A1
    优先权日:2021-04-16
    标题 :Synthesis of dimethyl-c17-32-alkyl sulfonium salts
    发明人:STROOT JOERG; ZHERSH SERHII; RIPENKO VASYL
    权利人:HELM AG
    摘要:The invention relates to a process for the preparation of a dimethyl-C 17-32 -alkyl sulfonium salt, preferably a dimethyl-C 17-32 -alkyl sulfonium halide, more preferably a dimethyl-C 17-32 -alkyl sulfonium chloride, still more preferably dimethyl octadecyl sulfonium chloride, the process comprising the steps of: providing a mixture of a C 17-32 -alkyl halide and dimethyl sulfide; and reacting the C 17-32 -alkyl halide with the dimethyl sulfide.

    专利号:US-10913702-B2
    优先权日:2018-01-15
    标 题:Method for cycloaddition of dimethyl muconate
    发明人:PARK JAE KYUN; PARK JEONG HO; CHAE HEE-IL
    权利人:SK CHEMICALS CO LTD
    摘要:A method for cycloaddition of dimethyl muconate is disclosed. According to the method, a direct transferring of a solid phase trans,trans-dimehtyl muconate into a reactor pre-filled with ethylene gas increases the efficiency of the reaction and suppress side reactions resulting an improvements in yield and purity. Furthermore, the method is capable of obtaining a high yield of dimethylcyclohex-2-en-1,4-dicarboxylate at a lower cost, and therefore is also useful for the mass synthesis of dimethyl terephthalate.

    专利号:US-10737239-B2
    优先权日:2015-11-27
    标题 :Ultrafast high space-time-yield synthesis of metal-organic frameworks
    发明人:BURCKHART JULIA; MARX STEFAN; ARNOLD LENA; HOFMANN CLAUS; Müller Ulrich
    权利人:BASF SE
    摘要:The invention relates to a process for the preparation of metal-organic frameworks (MOFs) in form of a homogenous powder, and a process wherein the metal-organic framework is molded into shaped bodies.

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    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献

    [参考文献]: Jung Hm, Et Al. Metabolic Engineering Of Klebsiella Pneumoniae For The Production Of Cis,Cis-Muconic Acid. Appl Microbiol Biotechnol. 2015;99(12):5217-5225.
    [参考文献]: Shin Ws, Et Al. Characterization Of A Non-Phosphotransferase System For Cis,Cis-Muconic Acid Production In Corynebacterium Glutamicum. Biochem Biophys Res Commun. 2018;499(2):279-284.
    [参考文献]: M A S Toledo, Et Al. Small-Angle X-Ray Scattering And In Silico Modeling Approaches For The Accurate Functional Annotation Of An Lysr-Type Transcriptional Regulator. Biochim Biophys Acta. 2013 Mar;1834(3):697-707.
    [参考文献]: Yuheng Lin, Et Al. Extending Shikimate Pathway For The Production Of Muconic Acid And Its Precursor Salicylic Acid In Escherichia Coli. Metab Eng. 2014 May:23:62-9.

    合成参考文献


    摘要:Taylor, R. E.; Diène, C. R.; Daly, E. M., Science of Synthesis, (2009) 46, 571.
    摘要:Schramm, M. P., Science of Synthesis, (2009) 46, 503.
    摘要:Aitken, R. A.; Aitken, K. M., Science of Synthesis, (2010) 47, 1034.
    摘要:Tin, S.; de Vries, J. G., Science of Synthesis: Catalytic Reduction in Organic Synthesis, (2017) 1, 236.
    参考文献:10.1007/s00253-002-0933-8
    摘要:Liu Z, Yang H, Huang Z, Zhou P, Liu S-. Degradation of aniline by newly isolated, extremely aniline-tolerant Delftia sp. AN3. Applied Microbiology and Biotechnology. 2002 Feb 14;58(5):679–82. doi: 10.1007/s00253-002-0933-8.
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