CAS: 50715-28-1; Cyclopentyl Carbonochloridate

相似化合物

68060-41-3 51422-76-5 2993448-84-1

上下游产品

phosgene Cyclopentanol bis(trichloromethyl) carbonate CyclopentamineN-cyclopentyloxycarbonyl-L-phenylalanineN-cyclopentyloxycarbonyl-L-phenylalanine cyclopentyl chloride cyclopentene cyclopentyloxycarbonylamino-phenyl-acetic acid

光气,环戊醇置于甲苯体系中,用 二氯甲烷,甲苯 作为反应溶剂,化学反应 3.0H,反应生成 氯甲酸环戊酯
参考文献:Substituted Oxotremorine Derivatives
标题:Substituted Oxotremorine Derivatives
摘要:本公开说明了具有氮,氧或硫基团的新型取代氧氮甲唑啉衍生物的公式i,以及这些衍生物的前药形式.这些化合物具有胆碱能活性.还公开了使用这些化合物治疗哺乳动物中枢神经系统疾病的方法,包含这些化合物的制药制剂以及制备这些化合物的过程. ##str1##

专利信息

专利号:WO-9700244-A1
优先权日:1995-06-19
标题 :Process for parallel synthesis of a non-peptide library
发明人：FRITZ JAMES E; KALDOR STEPHEN W
权利人:LILLY CO ELI; FRITZ JAMES E; KALDOR STEPHEN W
摘要:A process for the sequential preparation of a library of compounds having pharmaceutical usage. The process involves the sequential mixing of solution phase reagents, followed by scavenging of excess unreacted reagents with solid phase scavenging agents. The process is highly iterative and applicable for producing various ureas, thiureas, amides, carbonates and tertiary amines.

专利号:WO-2006109321-A1
优先权日:2005-04-15
标题:An improved process for the synthesis of palmidrol
发明人：SURI SANJAY; KASHYAP TAPAN; SINGH JAGAT
权利人:MOREPEN LAB LTD; SURI SANJAY; KASHYAP TAPAN; SINGH JAGAT
摘要:The process of this invention comprises preparing anhydride of palmitic acid and alkyl or cycloalkyl haloformate by any conventional method, reacting anhydride so formed with ethnolamine in-situ, and isolating the product by any known methods such as solvent recovery or filtration followed by purifying the title product by recrystallization using organic solvents if so desired.

专利号:US-5254558-A
优先权日:1991-08-15
标 题:Substituted 1,3-diazines as leukocyte elastase inhibitors
发明人：BERNSTEIN PETER R; EDWARDS PHILIP D; THOMAS ROYSTON M; VEALE CHRIS A; WARNER PETER; WOLANIN DONALD J
权利人:ICI PLC
摘要:The present invention relates to certain novel substituted heterocycles which are 1-pyrimidinylacetamide compounds of formula I, set out herein, which are inhibitors of human leukocyte elastase (HLE), also known as human neutrophil elastase (HNE), making them useful whenever such inhibition is desired, such as for research tools in pharmacological, diagnostic and related studies and in the treatment of diseases in mammals in which HLE is implicated. The invention also includes intermediates useful in the synthesis of these substituted heterocycles, processes for preparing the substituted heterocycles, pharmaceutical compositions containing such substituted heterocycles and methods for their use.

专利号:US-4734495-A
优先权日:1985-07-17
标 题 :Process and intermediates for beta-lactam antibiotics
发明人：EVANS DAVID A; SJOGREN ERIC B
权利人:HARVARD COLLEGE
摘要:1-Benzyl(or substituted benzyl)-3β-[4(S)-aryloxazolidin-2-one-3-yl]-4β-(2-arylvinyl)azetidin-2-ones are provided via cycloaddition of a 4(S)-aryloxazolidin-2-one-3-ylacetyl halide and an imine formed with a benzylamine and a 3-arylacrolein, e.g. cinnamaldehyde. The azetidinones are useful chiral intermediates in an asymmetric synthesis of 1-carba(1-dethia)-3-hydroxy-3-cephem-4-carboxylic acids and esters and to monocyclic β-lactam antibiotics.

专利号:US-4870169-A
优先权日:1985-07-17
标 题:Intermediates for beta-lactam antibiotics
发明人：EVANS DAVID A; SJOGREN ERIC B
权利人:HARVARD COLLEGE
摘要:1-Benzyl(or substituted benzyl)-3β-[4(S)-aryloxazolidin-2-one-3-yl]-4β-(2-arylvinyl)azetidin-2-ones are provided via cycloaddition of a 4(S)-aryloxazolidin-2-one-3-ylacetyl halide and an imine formed with a benzylamine and a 3-arylacrolein, e.g. cinnamaldehyde. The azetidinones are useful chiral intermediates in an asymmetric synthesis of 1-carba(1-dethia)-3-hydroxy-3-cephem-4-carboxylic acids and esters and to monocyclic β-lactam antibiotics.

专利号:US-4665171-A
优先权日:1985-07-17
标 题:Process and intermediates for β-lactam antibiotics
发明人：EVANS DAVID A; SJOGREN ERIC B
权利人:UNIV HARVARD
摘要:1-Benzyl (or substituted benzyl)-3β-[4(S)-aryloxazolidin-2-one-3-yl]-4β-(2-arylvinyl)azetidin-2-ones are provided via cycloaddition of a 4(S)-aryloxazolidin-2-one-3-ylacetyl halide and an imine formed with a benzylamine and a 3-arylacrolein, e.g. cinnamaldehyde. The azetidinones are useful chiral intermediates in an asymmetric synthesis of 1-carba(1-dethia)-3-hydroxy-3-cephem-4-carboxylic acids and esters and to monocyclic β-lactam antibiotics.