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CAS号105537-87-9 4-甲基-4,5-二氢哒嗪-3... | CAS号87668-16-4 3-Pyridazinecar... | CAS号61892-47-5 5-hydroxy-4-met... | CAS号105537-47-1 ethyl 2-methyl-... | CAS号859956-15-3 5-methyl-6-oxo-... | CAS号20441-73-0 ethyl 2-hydroxy... | CAS号90568-15-3 3-氨基-4-甲基哒嗪 | CAS号68206-04-2 3-氯-4-甲基哒嗪 | CAS号82426-93-5 3-肼基-4-甲基吡嗪5-Methyl-6-Oxo-1,4,5,6-Tetrahydro-Pyridazine-3-Carboxylic Acid置于溴,溶剂黄146体系中,化学反应生成 4-甲基-3(2H)-哒嗪酮
参考文献:Hydrazides Of Some Pyridazonyl Substituted Acids
标题:Hydrazides Of Some Pyridazonyl Substituted Acids
摘要:
DOI:10.1021/ja01583A043
专利信息
专利号:US-10000487-B2
优先权日:2015-11-20
标 题 :Heterocyclic compounds that inhibit the kinase activity of Mnk useful for treating various cancers
发明人:SPRENGELER PAUL A; REICH SEIGFRIED H; WEBBER STEPHEN E; ERNST JUSTIN T
权利人:EFFECTOR THERAPEUTICS INC
摘要:The present invention provides synthesis, pharmaceutically acceptable formulations and uses of compounds in accordance with Formula IA or Formula IB, as well as stereoisomers, tautomers or pharmaceutically acceptable salts thereof. n nFor Formula IA and Formula IB compounds A 1 , A 2 , A 3 , A 4 , W 1 , W 2 , Y, X, R 1 , R 2 , R 3 , R 4a , R 4b , R 5a , R 5b , R 6 , R 7 , R 8 , R 9 , R 9a , R 9b , R 10 and subscript n are as defined in the specification. The inventive Formula IA and Formula IB compounds are inhibitors of Mnk and find utility in any number of therapeutic applications, including but not limited to treatment of inflammation and various cancers.
专利号:EP-1600451-A2
优先权日:1999-11-12
标题 :Synthesis of 2'-deoxy-l-nucleosides
专利号:EP-1600452-A2
优先权日:1999-11-12
标题 :Synthesis of 2'-deoxy-L-nucleosides
专利号:EP-1634888-A2
优先权日:1999-11-12
标题 :Synthesis of 2'-deoxy-L-nucleosides
专利号:EP-1232166-A2
优先权日:1999-11-12
标 题:Synthesis of 2'-deoxy-l-nucleosides
专利号:WO-0134618-A2
优先权日:1999-11-12
标 题 :Synthesis of 2'-deoxy-l-nucleosides