CAS: 23445-02-5; (1R,4S,5R,6R,7S,10R)-4,10-Dimethyl-7-Isopropyltricyclo[4.4.0.01,5]Decane-4-Ol
- 英文名称(1R,4S,5R,6R,7S,10R)-4,10-Dimethyl-7-Isopropyltricyclo[4.4.0.01,5]Decane-4-Ol
- 中文名称(1R,4S,5R,6R,7S,10R)-4,10-二甲基-7-异丙基三环[4.4.0.01,5]癸烷-4-醇
- IUPAC名称(3S,3aR,3bR,4S,7R,7aR)-4-isopropyl-3,7-dimethyloctahydro-1H-cyclopenta[1,3]cyclopropa[1,2]benzen-3-ol
- CAS编号23445-02-5
- FDA UNII编号:9C9ZTS2B3U
- 分子式:C15H26O分子量:222.37
- 产品CID: 1176264
物理性质
- 熔点61-62 °C
- 沸点279.5±8.0 °C(预测)
- 密度1.00±0.1 g/cm3(预测)
- pKa:15.19±0.60(预测)
- LogP:4.55
- 储存条件Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
- 产品应用该化合物是一种天然的除虫素化合物,它存在于立方浆(PIPER CUBBA)的基本油中,一种用于传统医学的植物,具有抗微生物,抗炎和抗氧化特性,在治疗和化妆应用中都有用.CUBBOL机制涉及与细胞途径互动,以减少氧化性压力和调节炎症反应,提供保护,防止感染和组织损害.CUBABOL主要用于香水的生产,以及呼吸和消化疾病的自然补救.
MSDS等安全信息
合成工艺路线路线简述
海关参考信息
- 2905122000-异丙醇
2905143000-叔丁醇
2905141000-异丁醇
2905142000-仲丁醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-11352648-B2
优先权日:2017-01-26
标 题:Metabolic engineering for microbial production of terpenoid products
发明人：KUMARAN AJIKUMAR PARAYIL; LIM RYAN; DONALD JASON; TSENG HSIEN-CHUNG; SANTOS CHRISTINE NICOLE S; PHILIPPE RYAN
权利人:MANUS BIO INC
摘要:The invention relates to methods and bacterial strains for making terpene and terpenoid products, the bacterial strains having improved carbon pull through the MEP pathway and to a downstream recombinant synthesis pathway.
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
1: Chen SC, Jiang BC, Lu YJ, Chang CH, Wu TH, Lin SW, Yin HW, Lee TH, Hsu CH. Characterization and Crystal Structures of a Cubebol-Producing Sesquiterpene Synthase from Antrodia cinnamomea. J Agric Food Chem. 2023 Sep 6;71(35):13014-13023. doi: 10.1021/acs.jafc.3c00570. Epub 2023 Aug 11. 12(19):12123-12131. doi: 10.1021/acscatal.2c03155. Epub 2022 Sep 21.
3: Rabe P, Dickschat JS. The EIMS fragmentation mechanisms of the sesquiterpenes corvol ethers A and B, epi-cubebol and isodauc-8-en-11-ol. Beilstein J Org Chem. 2016 Jul 5;12:1380-94. doi: 10.3762/bjoc.12.132.
4: Schäfer E, Seibold PS, Bartram S, Trottmann F, Haensch VG, Gressler M, Chadeayne AR, Hertweck C, O'Connor SE, Hoffmeister D. A "Magic Mushroom" Multi- Product Sesquiterpene Synthase. Chembiochem. 2023 Nov 2;24(21):e202300511. doi: 10.1002/cbic.202300511. Epub 2023 Sep 12. 45(18):2901-4. doi: 10.1002/anie.200504543. 17(1):164. doi: 10.1186/s12934-018-1010-z.
合成参考文献
参考文献:10.1002/(sici)1099-1026(199909/10)14:5<312::aid-ffj835>3.0.co;2-b
摘要:da Silva MHL, Zoghbi MDGB, Andrade EHA, Maia JGS. The essential oils ofPeperomia pellucida Kunth andP. circinnata Link var.circinnata. Flavour Fragr. J. 1999 Sep;14(5):312–4. doi: 10.1002/(sici)1099-1026(199909/10)14:5<312::aid-ffj835>3.0.co;2-b.
参考文献:10.1080/10412905.1997.9700774
摘要:Baser KHC, Demirçakmak B, Duman H. Composition of the Essential Oils of ThreeTeucriumSpecies from Turkey. Journal of Essential Oil Research. 1997 Sep;9(5):545–9. doi: 10.1080/10412905.1997.9700774.
参考文献:10.1016/0305-0491(91)90141-y
摘要:Dai MC, Garson MJ, Coll JC. Biosynthetic processes in soft corals. I. A comparison of terpene biosynthesis in Alcyonium molle (Alcyoniidae) and Heteroxenia sp. (xeniidae). Comparative Biochemistry and Physiology Part B: Comparative Biochemistry. 1991 Jan;99(4):775–83. doi: 10.1016/0305-0491(91)90141-y.
参考文献:10.1080/10412905.1999.9701096
摘要:Baser KHC, Kürkçüoglu M, Duman H. Steam Volatiles of the Fruits ofPrangos bornmuelleriHub.-Mor. et Reese. Journal of Essential Oil Research. 1999 Mar;11(2):151–2. doi: 10.1080/10412905.1999.9701096.
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