CAS: 2227-64-7; 2-Bromo-3'-Nitroacetophenone

上下游产品

CAS号121-89-1 3-硝基苯乙酮 | CAS号86440-77-9 1-bromo-2-(3-ni... | CAS号70-11-1 2-溴苯乙酮 | CAS号586-39-0 3-硝基苯乙烯 | CAS号98-86-2 苯乙酮 | CAS号99-47-8 α-Chloro-3'-nit... | CAS号7697-37-2 硝酸 | CAS号36765-84-1 2-氨基-3'-硝基苯乙酮盐酸盐 | CAS号313231-71-9 3-imidazo[1,2-a... | CAS号143632-16-0 1-(2-deoxyribof... | CAS号5021-44-3 2-(3-硝基苯基)喹喔啉 | CAS号26031-71-0 1-(3-nitropheny... | CAS号89250-34-0 3-(2-甲基-1,3-噻唑-... | CAS号72802-41-6 2'-羟基-3-硝基苯乙酮 | CAS号6097-22-9 2-(3-硝基苯基)-2-氧代硫氰酸乙酯 | CAS号100989-61-5 1-[2-methyl-5-(... | CAS号103740-34-7 4-(3-氨基苯基)-噻唑-2-胺

1-溴-2-(3-硝基苯基)乙炔置于水体系中,用 1,2-二氯乙烷 用作溶剂,化学反应 14.0H,以90%的收率获得2-溴-3'-硝基苯乙酮
参考文献:一种有效的多相金 (I) 催化卤代炔烃水合反应生成α-卤代甲基酮
标题:一种有效的多相金 (I) 催化卤代炔烃水合反应生成α-卤代甲基酮
摘要:摘要 开发了一种高效的多相金(i)催化卤代炔烃的水合反应,在温和,中性条件下顺利进行,为合成多种高原子经济性,优异的α-卤代甲基酮提供了一条通用实用的途径.金(i)催化剂的收率和可回收性.所提出的方法为酮的经典 α-卤化提供了一种有吸引力的替代方法.图形概要
Doi:10.1080/00397911.2018.1528616

专利信息

专利号:US-11078163-B2
优先权日:2014-01-24
标 题 :Processes for the synthesis of substituted urea compounds
发明人：RUSSO DOMENICO; WAHNON JORGE BRUNO REIS; MATON WILLIAM; ESZENYI TIBOR
权利人:BIAL PORTELA & CA SA; BIAL PORTELA & Cª S A
摘要:The present invention concerns a process for preparing a compound having the Formula A; or a pharmaceutically acceptable salt or derivative thereof, or for preparing a substituted urea compound of Formula IIa, or a pharmaceutically acceptable salt or ester thereof, the process comprising the reaction of an imidazolyl intermediate of Formula IIa′ with a carbamoyl halide of the formula: R1R2NC(â•?O)Hal, wherein Hal represents Cl, F, I or Br, wherein the intermediate of Formula IIa′ is prepared by oxidation of the derivative of R5 and R6, R6-C(â•?O)CH2R5 to form a glyoxal intermediate R6-C(â•?O)(Câ•?O)R5, which is subjected to treatment with ammonium hydroxide and an aldehyde R8CHO to provide the intermediate of Formula IIa′ and wherein the compound substituents are as defined herein.

专利号:JP-6777542-B2
优先权日:2014-01-24
标题:Process for the synthesis of substituted urea compounds

专利号:RU-2760719-C2
优先权日:2014-01-24
标题:Method for synthesis of substituted urea compounds

专利号:CA-2936192-A1
优先权日:2014-01-24
标 题 :Processes for the synthesis of substituted urea compounds

专利号:US-2017001962-A1
优先权日:2014-01-24
标 题 :Processes for the Synthesis of Substituted Urea Compounds

专利号:US-2020140391-A1
优先权日:2014-01-24
标 题:Processes for the Synthesis of Substituted Urea Compounds