CAS: 198544-94-4; (R)-2-((((9H-Fluoren-9-yl)Methoxy)Carbonyl)Amino)-6-((Diphenyl(P-Tolyl)Methyl)Amino)Hexanoic Acid

相似化合物

167393-62-6 111061-54-2 1272755-60-8

专利信息

专利号:US-2024209034-A1
优先权日:2021-04-12
标题:Engineering peptides for a a vb6 integrin binding and related methods of use and synthesis
发明人：SELLERS DREW; CARDLE IAN; PUN SUZIE HWANG
权利人:UNIV WASHINGTON; SEATTLE CHILDRENS HOSPITAL D/B/A SEATTLE CHILDRENS RES INSTITUTE
摘要:Embodiments of the claimed invention are directed to synthetic peptides comprising an amino acid sequence of X 1 X 2 VX 3 NLRGDLQVLX 4 QKVCX 5 T (SEQ ID NO:18), wherein at least one of X 1 and X 2 is a cysteine, and wherein one or more of X 3 , X 4 , and X 5 is a non-natural amino acid. Also described are methods of using the claimed embodiments for inhibiting growth of a cancer cell overexpressing integrin αvβ6. Additionally, also described are methods of using the claimed embodiments for detecting a cancer cell overexpressing integrin αvβ6.

专利号:CN-107056894-B
优先权日:2017-05-26
标 题:A kind of method for fragment method solid-phase synthesis of ganirelix acetate

专利号:CN-107056894-A
优先权日:2017-05-26
标 题 :A kind of method for the solid-phase synthesis of ganirelix acetate by fragment method

专利号:WO-2022221144-A1
优先权日:2021-04-12
标题 :Engineered peptides for αvβ6 integrin binding and related methods of use and synthesis

专利号:US-10610608-B2
优先权日:2013-08-01
标题 :Modular imaging agents containing amino acids and peptides
发明人：SCHMITTHENNER HANS F; BEACH STEPHANIE; BARRETT TAYLOR; WEIDMAN CHELSEA
权利人:SCHMITTHENNER HANS F; BEACH STEPHANIE; BARRETT TAYLOR; WEIDMAN CHELSEA; ROCHESTER INSTITUTE TECH
摘要:Targeted molecular imaging agents (TMIAs) are derived from coupling together pre-formed amino acids with imaging agents attached to their side chains. These peptide-based imaging agents may synthesized from a single or multiple preformed amino acids containing multi-modal, multi-chelated metal, multi-dye imaging agents, or combinations of these, on the side chains of resultant peptides. These imaging amino acids or peptides may be conjugated directly, or activated, or attached to linkers to which targeting groups, such as peptides, proteins, antibodies, aptamers, or small molecule inhibitors, may be conjugated in the final steps of the synthesis to form a wide variety of TMIAs.

专利号:WO-2022221144-A9
优先权日:2021-04-12
标题 :Engineered peptides for αvβ6 integrin binding and related methods of use and synthesis