CAS: 15486-96-1; 3-Bromopropanoyl Chloride

相似化合物

625-36-5 4509-90-4 18791-02-1

上下游产品

CAS号590-92-1 3-溴丙酸 | CAS号18187-28-5 3-Bromopropioni... | CAS号105174-63-8 3-bromo-1-(3,4-... | CAS号35979-69-2 4-溴-2-甲基-2-丁醇 | CAS号21437-82-1 3-bromo-N-(4-me... | CAS号21437-86-5 3-bromo-N,N-dim... | CAS号29636-75-7 3-bromopropiophenone | CAS号814-68-6 丙烯酰氯 | CAS号627-18-9 3-溴-1-丙醇 | CAS号6320-96-3 3-溴丙酰胺 | CAS号16044-35-2 Propanamide,N,N... | CAS号33994-11-5 3-bromo-1-(4-me...

3-溴丙酸置于草酰氯,N,N-二甲基甲酰胺体系中,用 二氯甲烷 用作溶剂,化学反应 3.0H,反应生成3-溴丙酰氯
参考文献:钌卟啉催化串联and /铵叶立德形成和[2,3]-σ重排.精确合成(+/-)-Platynecine
标题:钌卟啉催化串联and /铵叶立德形成和[2,3]-σ重排.精确合成(+/-)-Platynecine
摘要:内消旋四(对甲苯基)卟啉合钌(II)羰基[ru Ii(ttp)(co)]可在重氮存在下催化重氮化合物(如重氮乙酸乙酯(eda))的催化分解,从而形成分子间sulf和内铵盐.烯丙基硫化物和胺.观测到[2,3]-σ重排产物的独家形成(70-80%的收率),而未检测到[1,2]-重排产物.Eda与二取代的烯丙基硫化物(如巴豆基硫化物)的ru催化反应产生了抗-和顺式-2-(乙硫基)-3-甲基-4-戊烯酸乙酯的等摩尔混合物.类似的" Eda + N,N-二甲基巴豆胺"反应提供了抗和非对映选择性为3:1的顺式-2-(n,N-二甲基氨基)-3-甲基-4-戊烯酸乙酯.观测到的[ru Ii(ttp)(co)]对内酯[2,3]-σ重排的催化活性与报道的涉及[rh 2(ch 3 Co 2)4 ]和[cu(acac)的实例相当2 ]作为催化剂.类似地,在[ru Ii]下,重氮系到烯丙基硫醚和胺上的重氮基团的分子内
Doi:10.1021/jo049540V

专利信息

专利号:US-2022389049-A1
优先权日:2019-10-04
标 题:Reversible terminators for dna sequencing and methods of using the same
发明人：JAIN MOTI; ZHOU WEI
权利人:CENTRILLION TECH INC
摘要:The present disclosure provides methods of sequencing polynucleotides and compounds, compositions for sequencing of polynucleotides, and synthesis of such compositions. The chemical compounds include nucleotides and their analogs which possess a sugar moiety comprising a cleavable chemical group capping the 3′-OH group and a base, but without covalently bounded dye. The cleavable chemical group is reactive to form covalent bond(s) with a dye used to confirm the presence of the expected base-pairing. The cleavable chemical group capping the 3′OH group can be removed together with the covalently bounded dye. Furthermore, after the cleavable chemical group is cleaved, the free 3′-OH group can be active in continued elongation. Example chemical compounds according to the present disclosure are shown as Formulas (II) and (V):

专利号:US-5679833-A
优先权日:1993-09-15
标 题:Synthesis of vinyl esters
发明人：BENN GERALD PHILIP; DOYLE JANET CATRINE; LITTLEWOOD PETER STUART
权利人:ALLIED COLLOIDS LTD
摘要:PCT No. PCT/GB93/01953 Sec. 371 Date Feb. 28, 1996 Sec. 102(e) Date Feb. 28, 1996 PCT Filed Sep. 15, 1993 PCT Pub. No. WO95/07879 PCT Pub. Date Mar. 23, 1995Vinyl ester of an alcohol (such as benzoin) is made by reaction of the alcohol with a 3-haloalkyl acid halide (such as 3-chloropropional chloride or bromide) in an anhydrous liquid reaction medium comprising an aprotic solvent (such as toluene) and a hydrogen halide acceptor (such as a tertiary amine) at a temperature of at least 20 DEG C.

专利号:US-2010210474-A1
优先权日:2007-09-17
标 题:Heterocyclic scaffolds useful for preparation of combinatorial libraries, libraries and methods for preparation thereof
发明人：GELLERMAN GARY
权利人:GELLERMAN GARY
摘要:Disclosed are heterocyclic scaffolds useful, for example, for solid-phase organic synthesis of combinatorial libraries and methods for the preparation thereof. Also disclosed are libraries, including combinatorial libraries, and methods for preparation thereof. Exemplified are the following scaffolds (I):

专利号:US-8399502-B2
优先权日:2008-09-17
标 题 :Analogs of indole-3-carbinol and their use as agents against infection
发明人：JONG LING; JIANG FAMING; LI GAOQUAN; MORTELMANS KRISTIEN
权利人:JONG LING; JIANG FAMING; LI GAOQUAN; MORTELMANS KRISTIEN; STANFORD RES INST INT
摘要:Compounds useful as antibacterial agents are provided. The compounds are analogs of indole-3-carbinol and have a backbone selected from dihydroindolo[2,3-b]carbazole, 2,2′-diindolylmethane, 2′,3-diindolylmethane, and 3,3′-diindolylmethane. The compounds are useful therapeutic and prophylactic treatment of bacterial infections in mammals. Methods of synthesis of the compounds are provided, as are pharmaceutical compositions containing the compounds.

专利号:US-6627744-B2
优先权日:1999-07-02
标 题 :Synthesis of glycodendrimer reagents
发明人：DAVIS BENJAMIN G; JONES JOHN BRYAN; BOTT RICHARD R
权利人:GENENCOR INT
摘要:The present invention relates to a chemically modified mutant protein including a cysteine residue substituted for a residue other than cysteine n a precursor protein, the substituted cysteine residue being subsequently modified by reacting the cysteine residue with a glycosylated thiosulfonate. Also a method of producing the chemically modified mutant protein is provided. The present invention also relates to a glycosylated methanethiosulfonate. Another aspect of the present invention is a method of modifying the functional characteristics of a protein including providing a protein and reacting the protein with a glycosylated methanethiosulfonate reagent under conditions effective to produce a glycoprotein with altered functional characteristics as compared to the protein. In addition, the present invention relates to methods of determining the structure-function relationships of chemically modified mutant proteins. The present invention also relates to synthetic methods for producing thio-glycoses, the thio-glycoses so produced, and to methods for producing glycodendrimer reagents.

专利号:US-2008293969-A1
优先权日:2005-11-22
标 题 :18F-Labeled Daa Analogues and Method of Labeling These Analogues as Positron Emission Tomography (Pet) Tracers For Imaging Peripheral Benzodiazepine Receptors
发明人：KARIMI FARHAD; LANGSTROM BENGT; RAHMAN OBAIDUR; ESTRADA SERGIO
权利人:GE HEALTHCARE LTD
摘要:Methods for selecting novel DAA analogues for a peripheral type benzodiazepine receptor were labeled with 18 F using one-step syntheses are provided. Analogues labeled with the 18 F using the one-step synthesis method are also provided. Additionally, the purification of the Br, I, Cl, TsO, MsO, or R f SO 3 precursors in the compound of formula (II) by solid phase extraction is provided as is the precursor compounds of formula (II). A kit claim for comprising an effective amount of an 18 F labeled compound, and pharmaceutically acceptable salts and solvates thereof are also provided.