CAS: 99747-74-7; Naphthalen-1-Yl Trifluoromethanesulfonate

该化合物是有机合成的一种多用途试剂,特别因其作为环烷基制剂的作用而受到重视,其三氯硝酸盐组群是一个优秀的离子组,有利于有效的核循环替代反应,包括铃木和Stille反应等交叉过程.该化合物在标准条件下保持稳定,确保了可靠的处理和储存.它与一系列核糖核化合物的高度反应,有助于在制药,农用化学和材料科学领域建立复杂的芳香框架.三氯酸盐组的电子抽取性质增强了其在重组选择性转换中的效用,为合成途径提供了精确的控制.

结构式图片

相似化合物

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欧盟法规

ECHA物质C&L通报

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合成工艺路线路线简述

  • 合成目标产物 1-Naphthyl Triflate 主要起始原料 Trifluoromethanesulfonyl Chloride And 1-Naphthol
  • (文献来源)合成步骤主要原料 Trifluoromethanesulfonyl Chloride 和 1-Naphthol
📜4-Chloronaphthalen-1-Yl Trifluoromethanesulfonate置于potassium Phosphate,Palladium Diacetate,3-(Tert-Butyl(Phenyl)Phosphaneyl)-2-Cyclohexyl-1-Methyl-1H-Indole,异丙醇体系中,用 四氢呋喃 作为反应溶剂,以78 %的收率获得产物1-萘基三氟甲磺酸酯
参考文献:Palladium-Catalyzed Deuterodehalogenation Of Halogenated Aryl Triflates Using Isopropanol-D8 As The Deuterium Source
标题:Palladium-Catalyzed Deuterodehalogenation Of Halogenated Aryl Triflates Using Isopropanol-D8 As The Deuterium Source
摘要:
DOI:10.1021/acs.Orglett.3C03281

海关参考信息

专利信息


专利号:US-8410301-B2
优先权日:2007-11-28
标题:Methods for the synthesis of organic sulfides by using sulfides and organic sulfur-indium complexes
发明人:LEE PHIL-HO
权利人:LEE PHIL-HO; KNU INDUSTRY COOPERATION FOUND
摘要:The present invention relates to a novel synthesis method for the formation of carbon-sulfur bonds by the reaction of an organic sulfur-indium complex with nucleophile in the presence of a palladium catalyst. The present invention provides a synthesis method to prepare several kinds of organic sulfides which are difficult to be prepared by the conventional synthesis methods. A short reaction time and quantitative yield are the advantages of this method. In addition, several kinds of organic sulfide can be prepared by the selection of nucleophile and organic sulfur-indium complex to be used.

专利号:US-2010234633-A1
优先权日:2007-11-28
标 题:Methods for the synthesis of organic sulfides by using sulfides and organic sulfur-indium complexes

专利号:WO-2009069888-A2
优先权日:2007-11-28
标 题 :Methods for the synthesis of organic sulfides by using sulfides and organic sulfur-indium complexes

专利号:US-6323366-B1
优先权日:1997-07-29
标 题:Arylamine synthesis
发明人:WOLFE JOHN P; AHMAN JENS; SADIGHI JOSEPH P; SINGER ROBERT A; BUCHWALD STEPHEN L
权利人:MASSACHUSETTS INST TECHNOLOGY
摘要:The present invention provides a method for the preparation of a wide range of primary arylamines. The arylamines are prepared in two efficient, straightforward transformations: 1) an activated aryl group and an imine group are combined, in the presence of a transition metal catalyst, under conditions wherein the transition metal catalyst catalyzes the formation of a carbon-nitrogen bond between the activated carbon of the arene and the imine nitrogen; and 2) the resulting N-aryl imine is transformed, via any of a number of standard protocols, to the primary arylamine. The method of the invention may also be exploited in the preparation of vinylamines.

专利号:US-10150111-B2
优先权日:2016-09-06
标题 :Method for catalytic synthesis of cinnamic acid with catalyst recycle

专利号:KR-20090036001-A
优先权日:2007-10-08
标题:Allene substituted unsaturated compounds and synthesis of them using indium

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✅ COA系统入驻 | 共享模式

合成参考文献


摘要:Schnürch, M.; Hämmerle, J.; Stanetty, P., Science of Synthesis Knowledge Updates, (2010) 1, 194.
摘要:Pilgrim, B. S.; Tucker, M. J., Science of Synthesis Knowledge Updates, (2019) 1, 317.
摘要:Virieux, D.; Ayad, T.; Pirat, J.-L.; Volle, J.-N., Science of Synthesis Knowledge Updates, (2018) 1, 280.
摘要:Shibasaki, M.; Ohshima, T.; Itano, W., Science of Synthesis: Stereoselective Synthesis, (2011) 3, 489.
摘要:Shibasaki, M.; Ohshima, T.; Itano, W., Science of Synthesis: Stereoselective Synthesis, (2011) 3, 491.
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