CAS: 52386-29-5; 6-Amino-2-Methoxypyrimidin-4(3H)-One

该化合物3 位置上含有两个氮原子的六人组成的芳香环 . 该化合物在6 位置和 甲基氧基(-NH2) 组 的氨基质组(-NH2) 和 甲基苯氧基化合物组 (-OCH3) 的2 , 有助于其独特的化学特性.这些功能组的存在表明,由于氨基氨基氨基化合物组群和甲基氧组可能显示出其潜在的生物活动,因此可能具有对药物研究的兴趣. 由于存在氨基-Pylimomimdin-化学领域相关的化合物应用,该化学多元化体-6-.

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25902-86-7 1193-22-2 56-06-4

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CAS号105-56-6 氰乙酸乙酯 | CAS号2440-60-0 O-甲基异脲 | CAS号105-34-0 氰乙酸甲酯 | CAS号64-17-5 乙醇 | CAS号18852-51-2 sodium salt of ... | CAS号873-83-6 6-氨基尿嘧啶 | CAS号90057-07-1 6-羟基-2-甲氧基-7-脱氮嘌呤 | CAS号94940-32-6 6-Amino-2-metho...

合成工艺路线路线简述

  • 合成目标产物 6-Amino-2-Methoxy-4(1H)-Pyrimidinone 主要起始原料 O-Methylisourea And Methyl Cyanoacetate
  • (文献来源)合成步骤主要原料 O-Methylisourea 和 Methyl Cyanoacetate
📜氰乙酸乙酯,O-甲基异脲置于sodium Ethanolate体系中,化学反应生成 6-氨基-2-甲氧基-4-嘧啶酮
参考文献:Engelmann,Chemische Berichte,1909,Vol. 42,P. 179
标题:Engelmann,Chemische Berichte,1909,Vol. 42,P. 179

海关参考信息

专利信息


专利号:US-2024317750-A1
优先权日:2021-06-24
标 题 :An Efficient Process for the Synthesis of Methylliberine and Polymorphs Thereof
发明人:KANUMURU RAHUL RAJU; SHAJI GEORGE KOCHUMALAYIL; VANA MURALI MOHANARAO; SURANENI RAVIKUMAR; ANINDYA SIL
权利人:FERTIS INDIA PVT LTD
摘要:The present invention discloses a synthetic procedure for the preparation of Methylliberine and its polymorphs thereof in a simple and efficient manner.

专利号:WO-2025133718-A1
优先权日:2023-12-22
标题 :An efficient process for the synthesis of paraxanthine
发明人:KANUMURU RAHUL RAJU; KOCHUMALAYIL SHAJI GEORGE; SURANENI RAVIKUMAR; VANA MURALI MOHANARAO
权利人:FERTIS INDIA PVT LTD
摘要:The processes disclosed are simple, economical for large scale industrial production resulting in high purity and quality of paraxanthine. Further the process produces high-purity paraxanthine suitable for various applications in the nutraceutical, pharmaceutical, and cosmetic industries.

专利号:WO-2022269624-A1
优先权日:2021-06-24
标 题:An efficient process for the synthesis of methylliberine and polymorphs thereof

专利号:EP-1401829-B1
优先权日:2001-06-15
标题 :Novel heterocyclic antibacterial compounds
发明人:ZHI CHENGXIN; WRIGHT GEORGE E
权利人:MICROBIOTIX INC
摘要:The invention provides heterocyclic organic compounds that inhibit bacterial DNA polymerase IIIC and type II bacterial topoisomerase. The invention further provides compounds that are useful as intermediates in the synthesis of such heterocyclic organic compounds. Syntheses and uses of such heterocyclic organic molecules are also described.

专利号:US-6777420-B2
优先权日:2001-06-15
标题 :Heterocyclic antibacterial compounds
发明人:ZHI CHENGXIN; WRIGHT GEORGE E
权利人:MICROBIOTIX INC
摘要:The invention provides heterocyclic organic compounds that inhibit bacterial DNA polymerase IIIC and type II bacterial topoisomerase. The invention further provides compounds that are useful as intermediates in the synthesis of such heterocyclic organic compounds. Syntheses and uses of such heterocyclic organic molecules are also described.

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合成参考文献


摘要:Wu, Y.-J., Science of Synthesis Knowledge Updates, (2012) 2, 291.
摘要:von Angerer, S., Science of Synthesis Knowledge Updates, (2011) 1, 318.
摘要:von Angerer, S., Science of Synthesis Knowledge Updates, (2011) 1, 250.
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