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CAS号15356-60-2 D-薄荷醇 | CAS号64-19-7 冰醋酸

📜D-薄荷醇置于12-Tungstophosphoric Acid Immobilized On [bmim][fecl4]体系中,化学反应 0.09H,反应生成 (1S)-(+)-乙酸薄荷酯
参考文献:H3Pw12O40@[bmim][fecl4]: A Green Catalytic System For Alkoxymethylation Of Alcohols And Their One-Pot Interconversion To Acetates And Tms-Ethers
标题:H3Pw12O40@[bmim][fecl4]: A Green Catalytic System For Alkoxymethylation Of Alcohols And Their One-Pot Interconversion To Acetates And Tms-Ethers
摘要:12-Tungstophosphoric Acid Immobilized On [bmim][fecl4] Was Found To Be An Efficient Catalyst For Chemoselective Methoxymethylation And Ethxoymethylation Of Alcohols And Also One-Pot Conversion Of Mom-Or Eom-Ethers To Their Corresponding Acetates And Tms-Ethers Under Thermal Conditions And Microwave Irradiation. These Procedures Were Simple,Rapid And The Corresponding Products Were Obtained In High Yields. The Catalyst Exhibited Remarkable Reactivity And Was Reusable.
DOI:10.1007/bf03249085

专利信息

专利号:US-6852711-B2
优先权日:1998-09-11
标题:HIV protease inhibitors
发明人：BOYER JR FREDERICK EARL; DOMAGALA JOHN MICHAEL; ELLSWORTH EDMUND LEE; GAJDA CHRISTOPHER ANDREW; HAGEN SUSAN ELIZABETH; LOVDAHL MICHAEL JAMES; LUNNEY ELIZABETH ANN; MARKOSKI LARRY JAMES; PRASAD JOSYULA VENKATA NAGENDR; TAIT BRADLEY DEAN
权利人:AGOURON PHARMA
摘要:The present invention relates to novel dihydropyrones with tethered heterocycles having improved pharmacologic properties which potently inhibit the HIV aspartyl protease blocking HIV infectivity. The dihydropyrones are useful in the development of therapies for the treatment of viral infections and diseases, including AIDS. The present invention is also directed to methods of synthesis of the dihydropyrones and intermediates useful in the preparation of the final compounds.