CAS: 313545-72-1; 2-Chloro-4-Fluorophenylboronic Acid

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CAS号101335-11-9 2-氯-4-氟-1-碘苯 | CAS号4590-52-7 7-氟-3,4-二氢喹啉-2(1H)-酮

2-氯-4-氟-1-碘苯置于盐酸,异丙基氯化镁体系中,用 四氢呋喃,乙醚,硼酸三甲酯 用作溶剂,化学反应生成2-氯-4-氟苯硼酸
参考文献:(Halo-Benzo Carbonyl)Heterocyclo Fused Phenyl P38 Kinase Inhibiting Agents
标题:(Halo-Benzo Carbonyl)Heterocyclo Fused Phenyl P38 Kinase Inhibiting Agents
摘要:根据化学公式(I)或其药物可接受的盐描述的化合物: 1 是p38的抑制剂,可用于治疗类风湿性关节炎等炎症性疾病.

专利信息

专利号:EP-3590340-B1
优先权日:2010-09-01
标 题:Intermediates for the synthesis of fungicidal pyrazoles

专利号:ES-2971524-T3
优先权日:2010-09-01
标 题 :Intermediates for the synthesis of fungicide pyrazoles

专利号:US-9856241-B2
优先权日:2013-07-03
标 题:Substituted benzofuranyl and benzoxazolyl compounds and uses thereof
发明人：BALOGLU ERKAN; SHACHAM SHARON; SENAPEDIS WILLIAM; MCCAULEY DILARA; LANDESMAN YOSEF; GOLAN GALI; KALID ORI; SHECHTER SHARON
权利人:KARYOPHARM THERAPEUTICS INC
摘要:The invention generally relates to substituted benzofuranyl and substituted benzoxazolyl compounds, and more particularly to a compound represented by Structural Formula (A): or a pharmaceutically acceptable salt thereof, wherein the variables are as defined and described herein. The invention also includes the synthesis and use of a compound of Structural Formula (A), or a pharmaceutically acceptable salt or composition thereof, e.g., in the treatment of cancer (e.g., mantle cell lymphoma), and other diseases and disorders.