CAS: 23313-21-5; Emodin-8-Beta-D-Glucoside
该化合物是天然生成的炭疽化合物,其特点是分子结构,包括附于异丁核的胶晶色色拉诺底,提高了溶性,生物利用率和可使用性.该产品一般呈现纯黄色至橙色,在水和甲醇等极溶剂中溶解.Emodin 8-O-D-Glucoprocranoside,因其潜在的药理特性而闻名,包括抗炎,抗氧化剂和抗癌活动,因此对药用化学和天然产品研究感兴趣.该物质存在于各种植物中,特别是传统医药中,突出其在草药治疗中的重要性.该化合物的生物活动归因于其调节各种信号路径的能力,尽管需要进一步研究以充分阐明其行动和治疗潜力的机制.与许多自然化合物一样,其具体影响可能因浓度,配制和研究的生物环境而不同.
- 英文名称Emodin-8-Beta-D-Glucoside
- 中文名称大黄素-8-β-D-吡喃葡萄糖苷
- IUPAC名称1,6-dihydroxy-3-methyl-8-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)anthracene-9,10-dione
- 其它别名Emodin-1 (8)-Monoglucoside; 1,6-Dihydroxy-3-Methyl-8-[(2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Oxan-2-Yl]Oxyanthracene-9,10-Dione; 9,10-Anthracenedione, 1-(.Beta.-D-Glucopyranosyloxy)-3,8-Dihydroxy-6-Methyl-; Emodin 8-
- CAS编号23313-21-5
- MFCD编号:MFCD01725365
- EINECS号:110-204-2
- FDA UNII编号:YY0Q8Q1T3H
- 分子式:C21H20O10分子量:432.38
- 产品CID: 1174868
- 产品分类天然产物 → 蒽醌
物理性质
MSDS等安全信息
欧盟法规
C&L通报上下游产品
UDP-glucose 1,6,8-trihydroxy-3-methyl-9,10-anthraquinone icariin合成工艺路线路线简述
- 合成目标产物 Emodin-8-Glucoside 主要起始原料 Uridine 5'-(Trihydrogen Diphosphate), Mono-Alpha-D-Glucopyranosyl Ester And Emodin
- (文献来源)合成步骤主要原料 Uridine 5'-(Trihydrogen Diphosphate), Mono-Alpha-D-Glucopyranosyl Ester 和 Emodin
📜尿苷(5')二氢二磷酰(1)-Alpha-D-葡萄糖,大黄素置于glycosyltransferase From Carthamus Tinctorius (L.) (Honghua) Recombinant体系中,用 二甲基亚砜 用作溶剂,化学反应 12.0H,以5.5 Mg的收率获得大黄素-8-β-D-吡喃葡萄糖苷
参考文献:Exploring The Catalytic Promiscuity Of A New Glycosyltransferase From Carthamus Tinctorius
标题:Exploring The Catalytic Promiscuity Of A New Glycosyltransferase From Carthamus Tinctorius
摘要:The Catalytic Promiscuity Of A New Glycosyltransferase (Ugt73Ae1) From Carthamus Tinctorius Was Explored. Ugt73Ae1 Showed The Capability To Glucosylate A Total Of 19 Structurally Diverse Types Of Acceptors And To Generate O-,S-,And N-Glycosides,Making It The First Reported Trifunctional Plant Glycosyltransferase. The Catalytic Reversibility And Regioselectivity Were Observed And Modeled In A One-Pot Reaction Transferring A Glucose Moiety From Icariin To Emodin. These Findings Demonstrate The Potential Versatility Of Ugt73Ae1 In The Glycosylation Of Bioactive Natural Products.
Doi:10.1021/ol502380P
海关参考信息
- 2905122000-异丙醇
2905310000-1,2-乙二醇
2905320000-1,2-丙二醇
2905399001-1,3-丙二醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
1: Dong X, Fu J, Yin X, Cao S, Li X, Lin L; Huyiligeqi; Ni J. Emodin: A Review of its Pharmacology, Toxicity and Pharmacokinetics. Phytother Res. 2016 Aug;30(8):1207-18. doi: 10.1002/ptr.5631. Epub 2016 May 18.
2: Semwal RB, Semwal DK, Combrinck S, Viljoen A. Emodin - A natural anthraquinone derivative with diverse pharmacological activities. Phytochemistry. 2021 Oct;190:112854. doi: 10.1016/j.phytochem.2021.112854. Epub 2021 Jul 24. 18(6):425-435. doi: 10.1016/S1875-5364(20)30050-9. 89(3):135-145. doi: 10.1159/000520281. Epub 2021 Dec 6.
5: Chen C, Lin Z, Liu W, Hu Q, Wang J, Zhuang X, Guan S, Wu X, Hu T, Quan S, Jin X, Shen J. Emodin accelerates diabetic wound healing by promoting anti- inflammatory macrophage polarization. Eur J Pharmacol. 2022 Dec 5;936:175329. doi: 10.1016/j.ejphar.2022.175329. Epub 2022 Oct 29.
合成参考文献
摘要:S109 | PARCEDC | List of 7074 potential endocrine disrupting compounds (EDCs) by PARC T4.2 | DOI:10.5281/zenodo.10944198
📝 需求与反馈
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