CAS: 21685-47-2; O-Methyl-D-Valine

相似化合物

7146-15-8 154674-67-6 4070-48-8

上下游产品

methanol D-Val-OH tert-butyl dicarbonatedi-tert-butyl dicarbonate (3S,6R)-6-Isopropyl-5,8-dimethoxy-1-phenyl-4,7-diaza-spiro[2.5]°Cta-1,4,7-trieneN-[(Ξ)-1-methoxycarbonyl-1-(2-phenyl-acetylamino)-ethyl]-D-valine methyl esterN-[(Ξ)-1-methoxycarbonyl-1-(2-phenyl-acetylamino)-ethyl]-D-valine methyl ester N-[(S)-2-methoxycarbonyl-2-(2-phenyl-acetylamino)-ethyl]-D-valine methyl esterN-[(S)-2-methoxycarbonyl-2-(2-phenyl-acetylamino)-ethyl]-D-valine methyl ester N-[(R)-2-methoxycarbonyl-2-(2-phenyl-acetylamino)-ethyl]-D-valine methyl esterN-[(R)-2-methoxycarbonyl-2-(2-phenyl-acetylamino)-ethyl]-D-valine methyl ester Z-Ala-D-Val-OMe

专利信息

专利号:US-8653282-B2
优先权日:2007-10-18
标 题:Preparation of dihydrothieno [3,2-D] pyrimidines and intermediates used therein
发明人：FRUTOS ROGELIO; KRISHNAMURTHY DHILEEPKUMAR; MULDER JASON ALAN; RODRIGUEZ SONIA; SENANAYAKE CHRIS HUGH; TAMPONE THOMAS G
权利人:FRUTOS ROGELIO; KRISHNAMURTHY DHILEEPKUMAR; MULDER JASON ALAN; RODRIGUEZ SONIA; SENANAYAKE CHRIS HUGH; TAMPONE THOMAS G; BOEHRINGER INGELHEIM INT
摘要:The invention relates to improved methods of preparing dihydrothienopyrimidines of formula 1, and intermediates thereof, (I) wherein X is SO or SO 2 , preferably SO, and wherein R A , R 1 , R 2 , R 3 , R 4 and R 5 have the meanings given in the description. The methods according to this invention are more suitable for large-scale synthesis of said compounds than prior methods because the new synthetic process avoids distillation and chromatographic purification between steps and results in a higher overall yield of the desired product.

专利号:US-9422321-B2
优先权日:2010-09-07
标题 :Pyrimidine nucleoside derivatives, synthesis methods and uses thereof for preparing anti-tumor and anti-virus medicaments
发明人：CHANG JUNBIAO; AN HAOYUN; YU XUEJUN; GUO XIAOHE
权利人:CHANG JUNBIAO; AN HAOYUN; YU XUEJUN; GUO XIAOHE; HIGH & NEW TECH RES CENTER HENAN ACAD OF SCIENCES; ZHENGZHOU GRANLEN PHARMATECH LTD; UNIV ZHENGZHOU
摘要:The present invention relates to the field of pharmacochemistry. Disclosed are fluorinated and azido-substituted pyrimidine nucleoside derivatives, particularly compounds of the formula shown below: n nAlso disclosed are methods of preparation and uses for these compounds. The compounds can be used for preparing medicaments for treating diseases such as tumors and viral infections, and can be used separately or in combination with other medicaments. The compounds also have effective activity against diseases such as tumors and viral infections, while having few side effects, and thus have potential application value.

专利号:US-10233182-B2
优先权日:2014-04-04
标题 :Substituted spirocyclic inhibitors of autotaxin
发明人：BABISS LEE; CLARK MATTHEW; KEEFE ANTHONY D; MULVIHILL MARK J; NI HAIHONG; RENZETTI LOUIS; RUEBSAM FRANK; WANG CE; XIE ZHIFENG; ZHANG YING
权利人:X RX INC
摘要:The present invention relates to compounds according to Formula I and pharmaceutically acceptable salts, synthesis, intermediates, formulations, and methods of disease treatment therewith, including cancer, lymphocyte homing, chronic inflammation, neuropathic pain, fibrotic diseases, thrombosis, and cholestatic pruritus, mediated at least in part by ATX.

专利号:US-2002077491-A1
优先权日:2000-09-05
标 题 :Methods for forming combinatorial libraries combining amide bond formation with epoxide opening
发明人：SHIPPS GERALD W; ROSNER KRISTIN E; MAKARA GERGELY M; WINTNER EDWARD A; NASH HUW M; FELSCH JASON S; PAL KOLLOL; LENZ GEORGE R
摘要:The invention relates to methods for forming combinatorial libraries. The invention provides methods suitable for the rapid and convenient synthesis of very large combinatorial libraries of small organic molecules. In particular, the invention provides a method for forming combinatorial libraries combining amide bond formation with epoxide opening.

专利号:JP-2011139667-A
优先权日:2010-01-07
标题:Dipeptide having proline and β-alanine at the N-terminus, and method for enzymatic synthesis of the cyclized dipeptide

专利号:CN-108129404-B
优先权日:2018-01-30
标题 :Synthesis method of chiral piperazinone derivative