CAS: 160590-40-9; 7-Methoxy-1H-Pyrrolo[2,3-C]Pyridine

相似化合物

17288-53-8 1190316-96-1 352434-16-3

上下游产品

4-[(2-di-N,N-methylamino)vinyl]-2-methoxy-3-nitropyridine 2-methoxy-3-nitropyridine vinyl magnesium bromide 2-chloro-3-nitro-4-methylpyridine 1-N-benzyloxymethyl-7-methoxypyrrolo[2,3-c]pyridine 1-N-benzyloxymethyl-3-bromo-7-methoxypyrrolo[2,3-c]pyridine (1S)-1-(1-N-benzyloxymethyl-7-methoxypyrrolo[2,3-c]pyridin-3-yl)-5-O-tert-butyldimethylsilyl-1,4-dideoxy-1,4-imino-2,3-O-isopropylidene-D-ribitol

📜2-甲氧基-3-硝基-4-甲基吡啶置于palladium On Activated Charcoal 氢气体系中,用 乙醇,N,N-二甲基甲酰胺 用作溶剂,130.0 °C,103.42 Kpa 条件下,反应 18.25H,反应生成7-甲氧基-6-氮杂吲哚
参考文献:将锂化的9-脱氮嘌呤衍生物加到碳水化合物环亚胺上:氮杂-C-核苷免疫抑制剂的聚合合成.
标题:将锂化的9-脱氮嘌呤衍生物加到碳水化合物环亚胺上:氮杂-C-核苷免疫抑制剂的聚合合成.
摘要:已经开发了在生物活性氮杂-C-核苷的容易会聚合成中将9-脱氮基-9-硫代嘌呤衍生物合成和添加至碳水化合物衍生的环亚胺6的方法.
Doi:10.1021/jo0155613

专利信息

专利号:US-2012245199-A1
优先权日:2009-12-23
标题:[4 [4-(aminomethyl-2-fluoro-phenyl)-piperidin-1-yl]-(1h-pyrrolo-pyridin-yl)-methanones and synthesis thereof
发明人：CHOI-SLEDESKI YONG MI; NIEDUZAK THADDEUS R; POLI GREGORY B; SHUM PATRICK WAI-KWOK; STOKLOSA GREGORY T; ZHAO ZHICHENG
权利人:CHOI-SLEDESKI YONG MI; NIEDUZAK THADDEUS R; POLI GREGORY B; SHUM PATRICK WAI-KWOK; STOKLOSA GREGORY T; ZHAO ZHICHENG; SANOFI SA
摘要:The present invention relates herein to compounds and compositions for the treatment and amelioration of inflammatory disease. Specifically the present invention relates to compounds that having a tryptase inhibition activity and the intermediates thereof, pharmaceutical compositions comprising such compounds, and a method of treating subjects suffering from a condition disease or disorder that can be ameliorated by the administration of an inhibitor of tryptase.