专利号:US-12281398-B2 优先权日:2022-02-07 标题:Microfluidic process for the general electrochemical synthesis of geminal dipseudohalide or halide-pseudohalide compounds 发明人:SCHROER THORSTEN G; LECROY GREGORY E; AGUILA MIGUEL; RODRIGUEZ MAYRA P; DOWNARD TYLER J; MACLEOD BRIANNA L 权利人:US GOV AIR FORCE; US AIR FORCE 摘要:A process for the microfluidic electrochemical synthesis of geminal dipseudohalide or halide-pseudohalide compounds comprising the steps ofpumping a solution comprising a compound of Formula Iinto a microfluidic electrochemical reactor in the presence of a base, one of a halide or pseudohalide salt (MY), and a mediator;applying an electrical current through the microfluidic electrochemical reactor; andperforming oxidative addition to create a geminal dipseudohalide or halide-pseudohalide compound of the general Formula II
专利号:US-5756419-A 优先权日:1995-09-25 标题 :Process for the conversion of synthesis gas in the presence of a catalyst comprising cobalt and additional elements 发明人:CHAUMETTE PATRICK; DIDILLON BLAISE 权利人:INST FRANCAIS DU PETROLE 摘要:The invention concerns the preparation of a catalyst comprising a support containing at least one oxide of the element Si, Al, Ti, Zr, Sn, Zn, Mg or Ln (where Ln is a rare earth), cobalt, at least one element A selected from the group formed by ruthenium, platinum, palladium and uranium, and at least one element B selected from the group formed by molybdenum and tungsten, characterized in that it comprises at least the following successive steps: n (1) formation of a precursor comprising at least cobalt and at least a portion of the support; n (2) at least partial reduction of the precursor in the presence of at least one reducing compound; and n (3) deposition of any part of compound present in the catalyst and not present in the precursor on the reduced precursor. n The invention also concerns the use of the catalyst in a process for the synthesis of C 5 + hydrocarbons from synthesis gas.
专利号:US-5786393-A 优先权日:1995-07-13 标题 :Liquid phase process for converting synthesis gas 发明人:CHAUMETTE PATRICK; BOUCOT PIERRE; GALTIER PIERRE 权利人:INST FRANCAIS DU PETROLE 摘要:In the synthesis of essentially linear saturated C5+ hydrocarbons from synthesis gas, the reactive gas phase circulating either as a downflow or as an upflow through a fixed bed catalytic reaction zone, an upflow of an inert liquid phase through said zone at a superficial flow rate of more than 0.01 cm/s, as compared to a downflow of liquid phase, increases the selectivity of the process to the formation of the desired C5+ cut.
专利号:US-5869541-A 优先权日:1996-03-08 标 题:Conversion of synthesis gas to hydrocarbons in the presence of a liquid phase 发明人:EUZEN JEAN-PAUL; HARTER ISABELLE; CHAUMETTE PATRICK 权利人:INST FRANCAIS DU PETROLE; AGIP PETROLI 摘要:A process for the synthesis of essentially linear saturated C5+ hydrocarbons from a gas phase comprising synthesis gas is described. The process comprises circulation of an inert liquid phase and said gas phase in a reaction zone, in which the reaction zone is provided with at least one means for introducing gas and liquid phases, and at least one means for extracting the hydrocarbon phase formed by the Fischer-Tropsch reaction, and characterized in that the reaction zone comprises at least one mixing means. Preferably, at least one mixing means is a static mixer. An apparatus for carrying out the described process is also described.
专利号:US-2013289145-A1 优先权日:2011-01-24 标题 :Catalyst for fischer-tropsch synthesis, production method therefor, and production method using fischer-tropsch synthesis catalyst 发明人:MIURA YASUTOMO; NAKASHIZU SHIGENORI 权利人:MIURA YASUTOMO; NAKASHIZU SHIGENORI 摘要:The catalyst for FT synthesis comprises manganese carbonate containing from 10 to 25% by mass of silica in terms of an oxide on the basis of the mass of the catalyst, not more than 6% by mass of an organic binder on the basis of the mass of the catalyst, and from 0.5 to 5% by mass of ruthenium in terms of a metal on the basis of the mass of the catalyst, wherein the catalyst has a surface area of 100 to 210 m 2 /g and a pore volume of 0.1 to 0.6 ml/g.
专利号:WO-2024059703-A1 优先权日:2022-09-16 标题:Covalently modified template-independent dna polymerase and methods of use thereof 发明人:SPRACHMAN MELISSA M; BRYAN CASSIE M; GRISWOLD JR; DOE ROBERT E; MORAN ISAAC; RECORDS WILLIAM C; MAGYAR ANDREW P; RODRIGUEZ JUAN CARLOS; COLEMAN RACHEL; DOYLE ROBERT 权利人:CHARLES STARK DRAPER LABORATORY INC 摘要:Provided herein are engineered terminal deoxynucleotidyl transferase (TdT) proteins with certain modifications, including mutations to confer thermal stability and to install an exposed amino acid residue to which a small molecule can be covalently tethered via bioconjugate chemistries such as click chemistry. Also provided herein are methods of nucleic acid molecule synthesis using engineered TdTs and nucleotide molecules attached to redox-cleavable linkers, wherein the engineered TdT incorporates the nucleotide molecule into a nucleic acid strand and is separated from the nucleotide molecule when the redoxcleavable linker is cleaved upon exposure to suitable electrochemical conditions. Also provided herein are engineered TdTs covalently attached to a nucleotide molecule via a tether and also nucleotide molecules comprising a redox-cleavable linker. Further provided herein are systems for enzymatic DNA synthesis comprising an engineered TdT, a redox-cleavable linker a redox shuttle solution, and two or more electrodes.