CAS: 1366416-29-6; N-[2-(1H-Indol-3-yl)Ethyl]-N-Methylprop-2-En-1-Amine

专利信息

专利号:WO-2010109472-A1
优先权日:2009-03-25
标题:Microbial bioconversion of arteannuin b to artemisinin by using streptomyces pactum
发明人：SREENIVASA RAO PARCHA
权利人:LAKSHMI NARASU MANGAMOORI; SREENIVASA RAO PARCHA
摘要:This invention discloses a novel method for the synthesis of artemisinin, an anti-malarial drug. The method involves bioconversion of arteannuin B, a biogenetic precursor of artemisinin to the later using an enzyme of Streptomyces pactum MTCC 3664.

专利号:US-7838053-B2
优先权日:2004-03-11
标题:Barley for production of flavor-stable beverage
发明人：BREDDAM KLAUS; OLSEN OLE; SKADHAUGE BIRGITTE; LOK FINN; KNUDSEN SOEREN; BECH LENE MOELSKOV
权利人:CARLSBERG AS
摘要:According to the invention, there is provided null-LOX-1 barley and plant products produced thereof, such as malt manufactured by using barley kernels defective in synthesis of the fatty acid-converting enzyme lipoxygenase-1. Said enzyme accounts for the principal activity related to conversion of linoleic acid into 9-hydroperoxy octadecadienoic acid, a lipoxygenase pathway metabolite, which-through further enzymatic or spontaneous reactions-may lead to the appearance of trans-2-nonenal. The invention enables brewers to produce a beer devoid of detectable trans-2-nonenal-specific off flavors, even after prolonged storage of the beverage.

专利号:US-6261811-B1
优先权日:1998-12-22
标 题 :Synthesis of natural product metabolites using immobilized fungal spores
发明人：HAMDY MOSTAFA K
权利人:UNIV GEORGIA RES FOUND
摘要:Natural product metabolites produced by fungi are synthesized using fungal spores that have been immobilized onto/into a support. Supports that can be used include loofah sponge, synthetic sponge, powdered cellulose paper, wood shavings, calcium alginate gel beads, agar gel beads, channeled aluminum beads, polypropylene beads and glass beads. Immobilizing the fungal spores provides accelerated production of the natural product metabolite in a standard bioreactor. Fungi that can be used include Penicillium cyclopium, Penicillium chrysogenum, Penicillium citrinum, Trichoderma viride, Aspergillus terreus and Monascus ruber. In a preferred embodiment, spores of Penicillium cyclopium NRRL 6233 immobilized with loofah sponge are cultured in a nutrient media for at least 4 days to produce compactin which is a hypocholesteremic agent.

专利号:US-9655377-B2
优先权日:2011-08-12
标题 :Methods of controlling fructan synthesis in plants
发明人：XUE GANGPING; MCINTYRE CATHRINE LYNNE; KOOIKER MAARTEN CHRISTIAAN
权利人:XUE GANGPING; MCINTYRE CATHRINE LYNNE; KOOIKER MAARTEN CHRISTIAAN; COMMW SCIENT IND RES ORG
摘要:The present invention relates to plants with increased levels of water soluble carbohydrates, particularly fructan, in the stem and leaf sheath. The present invention also provides methods of identifying and/or producing these plants. In particular, the present invention relates to a novel class of polypeptides designated MYB13 which upregulate the expression of enzymes involved in fructan synthesis. The present invention further relates to a novel promoter element that can be used to express genes predominantly in the stem and leaf sheath during the early reproductive stage of a plant.

专利号:US-9363959-B2
优先权日:2008-12-30
标 题 :Barley with reduced lipoxygenase activity and beverage prepared therefrom
发明人：SKADHAUGE BIRGITTE; LOK FINN; BREDDAM KLAUS; OLSEN OLE; BECH LETTE MØLSKOV; KNUDSEN SØREN
权利人:SKADHAUGE BIRGITTE; LOK FINN; BREDDAM KLAUS; OLSEN OLE; BECH LETTE MØLSKOV; KNUDSEN SØREN; CARLSBERG BREWERIES AS; HEINEKEN SUPPLY CHAIN BV
摘要:According to the invention, there is provided barley with total loss of functional lipoxygenase (LOX)-1 and LOX-2 enzymes, and plant products produced thereof, such as malt manufactured by using barley kernels defective in the synthesis of the fatty acid-dioxygenating enzymes LOX-1 and LOX-2. Said enzymes account for the principal activities related to dioxygenation of linoleic acid into 9- and 13-hydroperoxy octadecadienoic acid, respectively. 9-Hydroperoxy octadecadienoic acid represents a LOX pathway metabolite, which—through further enzymatic or spontaneous reactions—may lead to the appearance of trans-2-nonenal (T2N). The invention enables brewers to produce a beer having insignificant levels of stale, T2N-specific off-flavors, even after prolonged storage of the beverage.

专利号:US-11975061-B2
优先权日:2018-09-05
标题:Protective immunity enhanced Salmonella vaccine (PIESV) against Brucella spp
发明人：CURTISS III ROY
权利人:UNIV FLORIDA
摘要:Bacterial pathogens have evolved means to succeed as pathogens by infecting without recognition by receptors triggering innate immunity, by suppressing induction of immunity and by inducing immune responses to antigens that confer no protectives immunity. Embodiments described herein circumvent these abilities in Salmonella so as to provide a vector system that induces maximal protective immune responses. Another major problem in using live attenuated bacterial vaccine vectors is the accumulation of attenuating mutations that confer a virulence and safety but which decrease the ability of the vaccine to invade cells in the MALT to colonize and persist in internal effector lymphoid tissues. The embodiments disclosed herein solve this problem in multiple ways by using regulated delayed in vivo shut off of virulence genes, regulated delayed synthesis of recombinant protective antigens and regulated delayed lysis in vivo to confer biological containment with no persistence of vaccine cells and no survival if excreted.