CAS: 127-22-0; (3S,4Ar,6Ar,8Ar,12Ar,12Bs,14Ar,14Br)-4,4,6A,8A,11,11,12B,14B-Octamethyl-1,2,3,4,4A,5,6,6A,8,8A,9,10,11,12,12A,12B,13,14,14A,14B-Icosahydropicen-3-Ol
该化合物是主要存在于各种植物物种中,特别是包括dandelions在内的人类塔拉克斯库的三叶类化合物,其特点是复杂的四环结构,有助于其生物活动和潜在的治疗特性.Tarexerol一般是无色的黄色液体,可粉色黄色液体,有蜡质质,在水中溶解性较低,但在有机溶剂中可溶解.该化合物对潜在的抗炎,抗氧化剂和肝脏保护效应产生了兴趣,使其成为药理学和天然产品化学研究的课题.此外,在传统医学中,对焦炭素可能起到作用,并研究其对各种生物系统的影响.它存在于基本油类和提取物中,也突出其在天然产品和草药治疗领域的重要性.
- 英文名称(3S,4Ar,6Ar,8Ar,12Ar,12Bs,14Ar,14Br)-4,4,6A,8A,11,11,12B,14B-Octamethyl-1,2,3,4,4A,5,6,6A,8,8A,9,10,11,12,12A,12B,13,14,14A,14B-Icosahydropicen-3-Ol
- 中文名称异蒲公英赛醇
- IUPAC名称(3S,4aR,6aR,8aR,12aR,12bS,14aR,14bR)-4,4,6a,8a,11,11,12b,14b-octamethyl-1,2,3,4,4a,5,6,6a,8,8a,9,10,11,12,12a,12b,13,14,14a,14b-icosahydropicen-3-ol
- 其它别名Alnulin; Taraxerol [mi]; 27-Norolean-14-En-3-Ol, 13-Methyl-, (3Beta,13Alpha)-; Skimmiol; Isoolean-14-En-3Beta-Ol; Isoolean-14-En-3.Beta.-Ol; (3Beta)-D-Fr
- CAS编号127-22-0
- MFCD编号:MFCD13186859
- FDA UNII编号:A32778O852
- 分子式:C30H50O分子量:426.73
- 产品CID: 433348
- 产品分类天然产物 → 萜类
物理性质
MSDS等安全信息
上下游产品
taraxerone taraxeryl acetate Taraxerone ethyl acetatetaraxerol-3β-tosylate Taraxerol-acetat taraxeryl acetate taraxerone合成工艺路线路线简述
📜3β-E-P-Coumaroyltaraxerol置于氢氧化钾体系中,化学反应生成蒲公英萜醇
参考文献:Talapatra,Bani; Basak,Amit; Talapatra,Sunil K.,Journal Of The Indian Chemical Society,1981,Vol. 58,P. 814-815
标题:Talapatra,Bani; Basak,Amit; Talapatra,Sunil K.,Journal Of The Indian Chemical Society,1981,Vol. 58,P. 814-815
海关参考信息
- 2901210000-乙烯
2901220000-丙烯
2905122000-异丙醇
2905141000-异丁醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-9943544-B2
优先权日:2015-03-18
标 题:Process for bio synthesis of nano arsenic trioxide and its use in treatment of diseases including cancer
发明人：BENDALE YOGESH NARAYAN; BENDALE VINEETA YOGESH
权利人:BENDALE YOGESH NARAYAN; BENDALE VINEETA YOGESH
摘要:The present invention is a process for bio synthesis of nano arsenic trioxide defined by its low toxicity, higher bio availability and nano particle size with the aid of buttermilk, goat urine, dolichos biflorous and other plant materials such as ginger, momordica charantia and musa paradisiaca . The invention is carried out in different steps involving purification of crude form of arsenic trioxide by boiling it with buttermilk, goat urine and extract of dolichos biflorous in subsequent steps, followed by the trituration of the bio purified arsenic trioxide with extracts of ginger and momordica charantia in subsequent steps and heating of the dry product obtained after trituration with musa paradisiaca resulting in the production of novel nano arsenic trioxide. The product is effective in the treatment of various diseases including different types of cancer in animals and humans. The product obtained through the process is less toxic with higher bio availability.
专利号:US-2016271177-A1
优先权日:2015-03-18
标 题:Process for bio synthesis of nano arsenic trioxide and its use in treatment of diseases including cancer
专利号:EP-2897906-A1
优先权日:2012-09-20
标 题:Process for bio synthesis of nano arsenic trioxide and its use in treatment of diseases including cancers
专利号:EP-2897906-B1
优先权日:2012-09-20
标题 :Process for bio synthesis of nano arsenic trioxide and its use in treatment of diseases including cancers
发明人：BENDALE YOGESH NARAYAN; BENDALE VINEETA YOGESH
权利人:BENDALE YOGESH NARAYAN; BENDALE VINEETA YOGESH
专利号:WO-2014045083-A1
优先权日:2012-09-20
标题:Process for bio synthesis of nano arsenic trioxide and its use in treatment of diseases including cancers
专利号:KR-20150056848-A
优先权日:2012-09-20
标 题 :Process for bio synthesis of nano arsenic trioxide and its use in treatment of diseases including cancers
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
1: B Souza G, M Pontes CL, de O Costa G, F de Sousa N, Tizziani T, E Pollo LA, Dambrós BP, Scotti MT, Steindel M, Braga AL, Schirmeister T, F de Assis F, Sandjo LP. Inhibitory Effects of Mangifera indica Secondary Metabolites and Their Synthetic Derivatives against SARS-CoV-2 Mpro and NS2B/NS3 (ZIKV and DENV-2). ACS Omega. 2024 Oct 24;9(44):44624-44638. doi: 10.1021/acsomega.4c07148.
2: Zhao F, Piao J, Song J, Geng Z, Chen H, Cheng Z, Cui R, Li B. Traditional Chinese herbal formula, Fuzi-Lizhong pill, produces antidepressant-like effects in chronic restraint stress mice through systemic pharmacology. J Ethnopharmacol. 2024 Oct 31;338(Pt 1):119011. doi: 10.1016/j.jep.2024.119011. Epub ahead of print. 25(18):9952. doi: 10.3390/ijms25189952.
4: Ravi L, Sadhana V, Jain P, Godidhar Raghuram SK, Vaithilingam M, Manjunathan R, Krishnan AK, Kesavan MP. In silico analysis reveals α-amylase inhibitory potential of Taraxerol (Coccinia indica) and Epoxywithanolide-1 (Withania coagulans): a possible way to control postprandial hyperglycemia-induced endothelial dysfunction and cardiovascular events. In Silico Pharmacol. 2024 Sep 9;12(2):82. doi: 10.1007/s40203-024-00257-6.
合成参考文献
参考文献:10.1248/bpb.28.158
摘要:Akihisa T, Franzblau SG, Ukiya M, Okuda H, Zhang F, Yasukawa K, Suzuki T, Kimura Y. Antitubercular Activity of Triterpenoids from Asteraceae Flowers. Biological & Pharmaceutical Bulletin. 2005;28(1):158–60. doi: 10.1248/bpb.28.158.
📝 需求与反馈
尽可能描述清楚需求与问题信息
