CAS: 698-00-0; 2-Bromo-N,N-Dimethylaniline

上下游产品

CAS号615-36-1 2-溴苯胺 | CAS号74-88-4 碘甲烷 | CAS号121-69-7 N,N-二甲基苯胺 | CAS号50-00-0 甲醛 | CAS号77-78-1 硫酸二甲酯 | CAS号698-02-2 2-碘-N, N-二甲基苯胺 | CAS号1072901-09-7 N1-(2-(二甲基氨基)苯基... | CAS号22608-37-3 lithium,N,N-dim... | CAS号89291-23-6 2-(二甲氨基)苯硼酸 | CAS号224311-49-3 2-(二-叔丁基膦)-2'-(... | CAS号579-72-6 2-(二甲氨基)苯甲醛 | CAS号5339-18-4 Benzenamine,2-e... | CAS号121-69-7 N,N-二甲基苯胺 | CAS号100-66-3 苯甲醚 | CAS号108-88-3 甲苯 | CAS号2836-03-5 N,N-二甲基邻苯二胺

1-(2-二甲氨基苯基)丙醇置于溴,三丁基氧化锡体系中,用98%的收率获得产物2-溴-N,N-二甲基苯胺
参考文献:Synthesis Of Isobenzofuran Derivatives As Heterocyclic Analogues Of The Herbicidesindone B
标题:Synthesis Of Isobenzofuran Derivatives As Heterocyclic Analogues Of The Herbicidesindone B
摘要:The Target Compounds 21-27 Were Synthesized Via Bromination Of The N,N,1,1-Tetramethylisobenzofuranamines 13,15 And 16,Subsequent Bromine-Lithium Exchange And Reaction With Propanal Or Propanoyl Chloride,Respectively. In The Course Of Some Model Reactions Undertaken To Test A Synthetic Strategy Based On Directed Ortho-Lithiation Governed By The Dimethylamino-Group A Useful Synthesis Of The Ketone 3 Was Developed.
DOI:10.1002/prac.19943360411

专利信息

专利号:US-7205427-B2
优先权日:2002-06-04
标 题:Cross-coupling synthesis of alkyl (dialkylphenyl) indenes
发明人：BARNES HAMLIN H
权利人:BOULDER SCIENT CO
摘要:A cross-coupling synthesis of 2-alkyl-4-(2,6-dialkylphenyl)indenes is described. A 2-alkylidene is treated with a dialkylboronic acid in the presence of a catalyst. A feature of the invention is the use of a cross-coupling catalyst comprising palladium dichloride (1,5-cyclooctadiene) as a cross-coupling catalyst.

专利号:US-8110691-B2
优先权日:2006-06-14
标题 :Industrial process for the synthesis of 17α-acetoxy-11β-[4-(N,N-dimethyl-amino)-phenyl]-19-norpregna-4,9-diene-3,20-dione and new intermediates of the process
发明人：DANCSI LAJOSNE; VISKY GYOERGY; TUBA ZOLTAN; CSOERGEI JANOS; MOLNAR CSABA; MAGYARI ENDRENE
权利人:DANCSI LAJOSNE; VISKY GYOERGY; TUBA ZOLTAN; CSOERGEI JANOS; MOLNAR CSABA; MAGYARI ENDRENE; RICHTER GEDEON NYRT
摘要:A new industrial process for the synthesis of solvate-free 17α-acetoxy-11β-[4-(N,N-dimethyl-amino)-phenyl]-19-norpregna-4,9-diene-3,20-dione [CDB-2914] of formula (I) which is a strong antiprogestogene and antiglucocorticoid agent. The invention also relates to compounds of formula (VII) and (VIII) used as intermediates in the process.

专利号:US-2009187032-A1
优先权日:2006-06-14
标 题 :INDUSTRIAL PROCESS FOR THE SYNTHESIS OF 17alpha-ACETOXY-11beta-[4-(N,N-DIMETHYL-AMINO)-PHENYL]-19-NORPREGNA-4,9-DIENE-3,20-DIONE AND NEW INTERMEDIATES OF THE PROCESS

专利号:AU-2007258955-B2
优先权日:2006-06-14
标题:Industrial process for the synthesis of 17alpha-acetoxy-11beta-[4-(N,N-dimethyl-amino)- phenyl]-19-norpregna-4,9-diene-3,20-dione and new intermediates of the process

专利号:CA-2653552-A1
优先权日:2006-06-14
标 题:Industrial process for the synthesis of 17.alpha.-acetoxy-11.beta.-[4-(n,n-dimethyl-amino)-phenyl]-19-norpregna-4,9-diene-3,20-dione and new intermediates of the process

专利号:EP-2027140-B1
优先权日:2006-06-14
标题:Industrial process for the synthesis of 17 alpha -acetoxy-11 beta -[4-(n,n-dimethyl-amino)- phenyl]-19-norpregna-4,9-diene-3,20-dione and new intermediates of the process