专利号:US-8212056-B2 优先权日:2008-06-30 标 题 :Ligands for transition-metals and methods of use 发明人:KWONG FUK YEE; SO CHAU MING 权利人:KWONG FUK YEE; SO CHAU MING; UNIV HONG KONG POLYTECHNIC 摘要:The present invention relates to indolyl phosphine ligands, and methods of making such ligands utilizing phenyl hydrazines and aryl ketones as the starting material. The present invention further includes uses of the ligands in the synthesis of pharmaceuticals, materials, and agriculture.
专利号:US-8530689-B2 优先权日:2008-05-05 标 题 :Processes for the preparation of biphenyl compounds 发明人:PERCEC VIRGIL; ROSEN BRAD MATTHEW; WILSON DANIELA A; WILSON CHRISTOPHER J 权利人:PERCEC VIRGIL; ROSEN BRAD MATTHEW; WILSON DANIELA A; WILSON CHRISTOPHER J; UNIV PENNSYLVANIA 摘要:The invention concerns processes for the synthesis of a compound of the formula: wherein: R 1 and R 2 are each, independently, C 1 -C 12 alkyl, CO 2 R 3 , OR 4 , R 5 (OR 6 ), or C 6 -C 18 aryl; R 3 -R 6 are each, independently, C 1 -C 12 alkyl or C 6 -C 12 aryl; and n and m are each, independently, O or an integer from 1-5; said process comprising:—contacting a compound of the formula H0-R 7 -0H with BH 3 and a compound of the formula in the presence of a nickel-containing catalyst to produce a first product, where R 7 is a C 2 -C 12 hydrocarbon group and X is a halogen, OMs or OTs;—contacting the first product in situ with a compound of the formula: in the presence of a nickel-containing catalyst to produce a compound of formula I, where Z is a halogen.
专利号:CN-117088829-A 优先权日:2023-07-25 标 题 :Synthesis method of 1-isopropyl-4- (p-methoxyphenyl) piperazine or halogen acid salt thereof
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