CAS: 19013-30-0; 4-Methoxyphenyl Mesylate

该化合物是一种多用途有机化合物,通常用作制药和精美化学合成的中间体,其甲氧基和甲基功能组是将四甲基苯基细胞引入更复杂的分子的宝贵试剂. 环氧组增强反应性,促进有效的核生殖替代反应. 由于其稳定性和可预测的反应性,该化合物对于开发活性药物成分(API)和特殊化学品特别有用. 它通常在受控制的条件下处理,以确保合成应用的纯度和最佳性能. 它的一贯质量和可靠的再活动特征使其成为研究和工业规模工艺的首选.

结构式图片

上下游产品

CAS号124-63-0 甲基磺酰氯 | CAS号150-76-5 4-甲氧基苯酚(MEHQ) | CAS号25236-64-0 甲磺酸2,2,2-三氟乙酯 | CAS号150-78-7 对苯二甲醚 | CAS号64128-17-2 (4-methoxypheno... | CAS号17488-65-2 4-苯基-3-丁烯-2-醇 | CAS号123-31-9 对苯二酚 | CAS号3762-33-2 (4-甲氧基苯基)膦酸二乙酯 | CAS号171364-79-7 4-甲氧基苯硼酸频那醇酯 | CAS号3989-14-8 [(4-甲氧基苯基)乙炔基]三甲基硅烷 | CAS号213596-33-9 4-甲氧基苯硼酸新戊二醇酯 | CAS号64-18-6 甲酸 | CAS号75-75-2 甲基磺酸 | CAS号100-66-3 苯甲醚 | CAS号150-76-5 4-甲氧基苯酚(MEHQ) | CAS号150-78-7 对苯二甲醚 | CAS号53040-92-9 4-甲氧基-4-甲基-联苯

合成工艺路线路线简述

    📜对苯二酚置于吡啶,甲醇,Sodium,三乙胺体系中,化学反应 220.8H,反应生成4-甲氧基苯基甲磺酸
    参考文献:Selected Sulfonyl Compounds As Anticancer/antimalarial Agents
    标题:Selected Sulfonyl Compounds As Anticancer/antimalarial Agents
    摘要:对一系列磺酰基苯酚和磺酰基芳基甲基醚的合成和生物测试表明,对甲氧基苯基对甲苯磺酸酯是一种选择性很强的有效抗疟药物,对人类皮肤癌细胞具有明显的活性.采用反击策略可以从二氢醌的双(对甲苯磺酸盐)中直接制备出所需的对甲苯磺酸盐醚.
    Doi:10.1071/ch03073

    海关参考信息

    专利信息


    专利号:US-8212056-B2
    优先权日:2008-06-30
    标 题 :Ligands for transition-metals and methods of use
    发明人:KWONG FUK YEE; SO CHAU MING
    权利人:KWONG FUK YEE; SO CHAU MING; UNIV HONG KONG POLYTECHNIC
    摘要:The present invention relates to indolyl phosphine ligands, and methods of making such ligands utilizing phenyl hydrazines and aryl ketones as the starting material. The present invention further includes uses of the ligands in the synthesis of pharmaceuticals, materials, and agriculture.

    专利号:US-8530689-B2
    优先权日:2008-05-05
    标 题 :Processes for the preparation of biphenyl compounds
    发明人:PERCEC VIRGIL; ROSEN BRAD MATTHEW; WILSON DANIELA A; WILSON CHRISTOPHER J
    权利人:PERCEC VIRGIL; ROSEN BRAD MATTHEW; WILSON DANIELA A; WILSON CHRISTOPHER J; UNIV PENNSYLVANIA
    摘要:The invention concerns processes for the synthesis of a compound of the formula: wherein: R 1 and R 2 are each, independently, C 1 -C 12 alkyl, CO 2 R 3 , OR 4 , R 5 (OR 6 ), or C 6 -C 18 aryl; R 3 -R 6 are each, independently, C 1 -C 12 alkyl or C 6 -C 12 aryl; and n and m are each, independently, O or an integer from 1-5; said process comprising:—contacting a compound of the formula H0-R 7 -0H with BH 3 and a compound of the formula in the presence of a nickel-containing catalyst to produce a first product, where R 7 is a C 2 -C 12 hydrocarbon group and X is a halogen, OMs or OTs;—contacting the first product in situ with a compound of the formula: in the presence of a nickel-containing catalyst to produce a compound of formula I, where Z is a halogen.

    专利号:CN-117088829-A
    优先权日:2023-07-25
    标 题 :Synthesis method of 1-isopropyl-4- (p-methoxyphenyl) piperazine or halogen acid salt thereof

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:Kwiecień, H., Science of Synthesis Knowledge Updates, (2014) 4, 293.
    摘要:Rudzinski, D. M.; Leadbeater, N. E., Science of Synthesis Knowledge Updates, (2012) 1, 374.
    摘要:Suginome, M.; Ohmura, T., Science of Synthesis: Cross Coupling and Heck-Type Reactions, (2012) 1, 171.
    摘要:Sandrock, D. L., Science of Synthesis: Cross Coupling and Heck-Type Reactions, (2012) 1, 349.
    摘要:Murata, M., Science of Synthesis: Cross Coupling and Heck-Type Reactions, (2012) 2, 440.
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