CAS: 18807-71-1; Benzyl N-(2-Aminoethyl)Carbamate Hydrochloride

上下游产品

CAS号77153-05-0 N-cbz-N'-b°C-乙二胺 | CAS号886-64-6 Z-β-丙氨酸酰胺 | CAS号18807-67-5 乙烷-1,2-二基二氨基甲酸二苄酯 | CAS号501-53-1 氯甲酸苄酯 | CAS号107-15-3 乙二胺

📜Benzyl (2-Azidoethyl)Carbamate置于1,3-Diphenyldisiloxane,三苯基膦,水,盐酸体系中,用 1,4-二氧六环 用作溶剂,化学反应 24.0H,以85%的收率获得n-苄氧羰基乙二胺盐酸盐
参考文献:在室温下催化施陶丁格的还原
标题:在室温下催化施陶丁格的还原
摘要:我们报道了在室温下有效的staudinger催化还原反应,该反应能够以优异的收率从叠氮化物制备结构多样的胺.该反应基于催化量的三苯基膦作为膦源和二苯基二硅氧烷作为还原剂的使用.我们的staudinger催化还原具有很高的化学选择性,例如叠氮化物相对于其他常见官能团(包括腈,烯烃,炔烃,酯和酮)的还原.
Doi:10.1021/acs.Joc.9B00831

专利信息

专利号:US-7825244-B2
优先权日:2005-06-10
标题:Intermediates useful in the synthesis of alkylquinoline and alkylquinazoline kinase modulators, and related methods of synthesis
发明人：BAINDUR NAND; GAUL MICHAEL DAVID; KREUTTER KEVIN DOUGLAS; XU GUOZHANG
权利人:JANSSEN PHARMACEUTICA NV
摘要:The invention is directed to alkylquinoline and alkylquinazoline compounds of Formula C: n nwherein R 1 , R 2 , R 99 , and X are as defined herein, the use of such compounds in the synthesis of protein tyrosine kinase inhibitors, particularly inhibitors of FLT3 and/or c-kit and/or TrkB.

专利号:US-2007021436-A1
优先权日:2005-06-10
标 题 :Intermediates useful in the synthesis of alkylquinoline and alkylquinazoline kinase modulators, and related methods of synthesis

专利号:CA-2611219-A1
优先权日:2005-06-10
标题 :Intermediates useful in the synthesis of alkylquinoline and alkylquinazoline kinase modulators and related methods of synthesis

专利号:AU-2006258056-A1
优先权日:2005-06-10
标 题:Intermediates useful in the synthesis of alkylquinoline and alkylquinazoline kinase modulators and related methods of synthesis

专利号:KR-20080033234-A
优先权日:2005-06-10
标 题 :Intermediates useful in the synthesis of alkylquinoline and alkylquinazoline kinase modulators and related methods of synthesis

专利号:WO-2006135646-A1
优先权日:2005-06-10
标题:Intermediates useful in the synthesis of alkylquinoline and alkylquinazoline kinase modulators and related methods of synthesis