CAS: 1075-06-5; Phenylglyoxal Hydrate

相似化合物

7466-72-0 859775-25-0 197447-05-5

上下游产品

CAS号98-86-2 苯乙酮 | CAS号1074-12-0 苯基丙醇水合物 | CAS号536-74-3 苯乙炔 | CAS号582-24-1 2-羟基苯乙酮 | CAS号3282-32-4 2-二氮杂-1-苯乙酮 | CAS号292638-84-7 phenylene-ethylene | CAS号67972-70-7 (2S)-2-amino-5-... | CAS号82408-31-9 2-hydroxy-2-((2... | CAS号92-71-7 2,5-二苯基噁唑 | CAS号19027-81-7 2-(4-bromopheny... | CAS号93-56-1 (±)-1-苯基-1,2-乙二醇 | CAS号611-73-4 苯甲酰甲酸 | CAS号25555-27-5 α-(Piperidinoim... | CAS号24285-73-2 Oxazole,2-(4-ch... | CAS号23448-86-4 6-phenyl-2H-1,2... | CAS号21210-43-5 (S)-(+)-扁桃酸甲酯 | CAS号20698-91-3 D-(-)-扁桃酸甲酯 | CAS号670-95-1 4-苯基咪唑

苯基丙醇水合物置于水体系中,化学反应 5.0H,以9.87 G的收率获得3,4-二羟基苯乙酮
参考文献:具有生物活性的新型2,8-二取代的吡啶并[3,4-B]吡嗪的便捷合成
标题:具有生物活性的新型2,8-二取代的吡啶并[3,4-B]吡嗪的便捷合成
摘要:通过合适的二氨基吡啶与α-酮醛等价物之间的初步缩合反应,已开发出一种选择性合成2,8-二取代的吡啶并[3,4-B ]吡嗪的方法.着眼于在c-8上的官能化,已经合成了2-芳基-8-溴-和8-氨基-2-芳基吡啶并[3,4-B ]吡嗪.苯胺,酰胺和脲已从关键中间体的8位引入.发现由此制备的2,8-二取代的吡啶并[3,4-B ]吡嗪具有生物学意义. 吡啶并[3,4-B ]吡嗪-吡啶-硫缩醛-苯乙二醛-区域选择性-缩合
Doi:10.1055/s-0031-1289613

专利信息

专利号:US-2022048879-A1
优先权日:2020-08-13
标 题:Synthesis of small molecules inspired by Phomoxanthone A
发明人：ALI RAMEEZ; MATTSON ANITA
权利人:WORCESTER POLYTECH INST
摘要:Methods, compositions, and kits are provided for synthesizing bioactive chromane, the method including: constructing a tertiary ether stereocenter enantioselectively by catalyzed alkynylation of a substituted chromenone to obtain a chromanone; reducing alkyne and ketone in the chromanone to obtain a chroman; and converting ester to methyl group thereby obtaining chromane.

专利号:US-3953604-A
优先权日:1972-01-14
标 题:1-(2-Substituted-chromonyloxy)-2-hydroxy-3-(substituted phenoxy)propanes
发明人：WARREN BRIAN THOMAS; SPICER JOHN WILLIAM
权利人:MILES LAB
摘要:Definitions: in the following Formulae I, II and IV, R 1 represents hydrogen, alkyl of 1 to 4 carbon atoms, or a nontoxic cation, while each of R 2 , R 3 , R 4 , R 5 , and R 6 symbolizes hydrogen, alkyl of 1 to 4 carbon atoms, alkoxy of 1 to 4 carbon atoms, carboxy, carbalkoxy of 1 to 4 carbon atoms, trihalomethyl, halogen, nitro or cyano. n Certain 1-(2-substituted-chromon-yloxy)-2-hydroxy-3-(substituted-phenoxy)propanes (Formula I), ##SPC1## n can be synthesized from intermediate bis-(substituted-phenoxy)propanes (Formula II), ##SPC2## n by condensation with diethyl oxalate in the presence of sodium ethoxide followed by cyclization with a mixture of glacial acetic acid and concentrated sulfuric or a mixture of concentrated hydrochloric acid and a lower alcohol containing up to 4 carbon atoms. n The bis-(substituted-phenoxy)propane intermediates (Formula II) are prepared by reacting a dihydroxyacetophenone (Formula III), ##SPC3## n with a (substituted-phenyl)glycidyl ether (Formula IV), ##SPC4## n in an organic solvent in the presence of a catalyst. n The 1-(2-substituted-chromon-yloxy)-2-hydroxy-3-(substituted-phenoxy)propanes (Formula I) are useful in the treatment of allergic conditions in mammals. The bis-(substituted-phenoxy)propanes (Formula II) are useful as intermediates in the synthesis of the latter compounds. Methods of preparing compounds having Formulae I and II are described. Methods of treating allergic conditions in mammals utilizing compounds of Formula I are also disclosed.

专利号:US-3928347-A
优先权日:1968-11-08
标 题:Pyrazinylmalonic acid esters and salts and pyrazinylacetic acids, esters and salts
发明人：SCHWARTZ NORMAN; MOHRBACHER RICHARD J
权利人:MCNEILAB INC
摘要:The compound, 2,3-diphenyl-5-ethylpyrazine, useful as a precursor in the synthesis of those compounds of the class of pyrazine, arylpyrazine, diphenylpyrazine, and cycloalkylpyrazine malonates, acetates, acetamides, and acetic acids, useful for their ultraviolet light absorption properties.

专利号:US-4046763-A
优先权日:1968-11-08
标题:2,3-Diphenyl-5-ethylpyrazine
发明人：SCHWARTZ NORMAN; MOHRBACHER RICHARD J
权利人:MCNEILAB INC
摘要:The compound 2,3-diphenyl-5-ethyl-pyrazine, useful as a precursor in the synthesis of those compounds of the class of pyrazine, arylpyrazine, diphenylpyrazine, and cycloalkylpyrazine malonates, acetates, acetamides, and acetic acids, useful for their ultraviolet light absorption properties.

专利号:CN-104230784-B
优先权日:2014-09-02
标题 :Synthesis of 1-aryl-2-(3-methyl-2-indolyl)-1,2-ethanedione derivatives

专利号:CN-104230784-A
优先权日:2014-09-02
标题 :Synthesis of 1-aryl-2-(3-methyl-2-indolyl)-1,2-ethanedione derivatives