CAS: 76375-60-5; (3R,4R,5R,6R)-3-Acetamido-6-(Acetoxymethyl)Tetrahydro-2H-Pyran-2,4,5-Triyl Triacetate

相似化合物

7784-54-5 76375-61-6 7772-79-4

上下游产品

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2-乙酰氨基-2-脱氧-D-吡喃半乳糖 反应生成 D-半乳糖胺五乙酸酯
参考文献:Hasegawa,Akira;Ogawa,Masayuki;Ishida,Hideharu;Kiso,Makoto,J. Carbohydr. Chem.,9,(1990) N,C. 393-414
标题:Hasegawa,Akira;Ogawa,Masayuki;Ishida,Hideharu;Kiso,Makoto,J. Carbohydr. Chem.,9,(1990) N,C. 393-414

专利信息

专利号:US-4362720-A
优先权日:1977-04-14
标题:Synthesis of 2-amino-2-deoxyglycoses and 2-amino-2-deoxyglycosides from glycals
发明人：LEMIEUX RAYMOND U; RATCLIFFE R MURRAY
权利人:CHEMBIOMED LTD
摘要:O-acetylated glycals react with ceric ammonium nitrate in the presence of sodium azide to provide, in good yield, O-acetylated 2-azido-2-deoxy glycosyl nitrates. These nitrates can be used to prepare 2-amino-2-deoxy sugars, such as D-galactosamine and lactosamine. The O-acetylated 2-azido-2-deoxy glycosyl nitrates can alternately be converted to O-acetylated 2-azido-2-deoxy glycosyl halides which are useful in the preparation of O-acetylated 2-azido-2-deoxy glycosides, which in turn can be reduced to 2-amino-2-deoxy glycosides. Of particular interest are the syntheses of 2-amino-2-deoxy glycosides which correspond to the terminal units of the antigenic determinant for the human A blood group. Attachment of these glycosides to a solid support provides immunoabsorbents which efficiently and preferentially absorb anti-A antibodies from blood plasma.

专利号:US-4308376-A
优先权日:1977-04-14
标 题 :Synthesis of 2-amino-2-deoxyglycoses and 2-amino-2-deoxyglycosides from glycals
发明人：LEMIEUX RAYMOND U; RATCLIFFE R MURRAY
权利人:CHEMBIOMED LTD
摘要:O-acetylated glycals react with ceric ammonium nitrate in the presence of sodium azide to provide, in good yield, O-acetylated 2-azido-2-deoxy glycosyl nitrates. These nitrates can be used to prepare 2-amino-2-deoxy sugars, such as D-galactosamine and lactosamine. The O-acetylated 2-azido-2-deoxy glycosyl nitrates can alternately be converted to O-acetylated 2-azido-2-deoxy glycosyl halides which are useful in the preparation of O-acetylated 2-azido-2-deoxy glycosides, which in turn can be reduced to 2-amino-2-deoxy glycosides. Of particular interest are the syntheses of 2-amino-2-deoxy glycosides which correspond to the terminal units of the antigenic determinant for the human A blood group. Attachment of these glycosides to a solid support provides immunoabsorbents which efficiently and preferentially absorb anti-A antibodies from blood plasma.

专利号:US-4195174-A
优先权日:1977-04-14
标题 :Synthesis of 2-amino-2-deoxyglycoses and 2-amino-2-deoxyglycosides from glycals