CAS: 719-60-8; 3-(2,3,4,5,6-Pentafluorophenyl)-2-Propenoic Acid

该化合物是一种有机化合物,其独特的结构特征是含有一种附于一种丙基酸协会的高度氟化联苯集团,其独特结构包括一个高度氟化联苯集团,在苯环上存在五氟原子,严重影响其化学特性,造成高电子密度,并改变其相对于非氟类比的再活性.该化合物通常具有高热稳定性和低挥发性,适合材料科学和有机合成的各种应用.其酸性可归因于箱式酸功能集团,使其能够参与酸基反应.此外,氟化结构可增强有机溶剂的脂性和可变性.由于这些特性,3-(2,3,4,5,5,6-Penta-Pentfrofen)-2-丙基酸对先进材料,药品和农用化学物的开发很感兴趣,因为氟化合物的性通常表现和功效提高.

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CAS号344-04-7 溴五氟苯 | CAS号827-15-6 五氟碘苯 | CAS号141-82-2 丙二酸 | CAS号653-37-2 五氟苯甲醛 | CAS号108-24-7 乙酸酐 | CAS号54081-32-2 (2E)-3-(Pentafl...

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    📜2,3,4,5,6-五氟碘苯置于吡啶体系中,化学反应生成 无氟肉桂酸
    参考文献:173.芳族多氟化合物.第八部分 五氟苯甲醛及相关的五氟苯基酮和羧酸
    标题:173.芳族多氟化合物.第八部分 五氟苯甲醛及相关的五氟苯基酮和羧酸
    摘要:
    DOI:10.1039/jr9610000808

    海关参考信息

    专利信息


    专利号:US-6531470-B1
    优先权日:1998-01-23
    标题:Oxazolidinone combinatorial libraries, compositions and methods of preparation
    发明人:GORDEEV MIKHAIL F; LUEHR GARY W; PATEL DINESH V; NI ZHI-JIE; GORDON ERIC
    权利人:UPJOHN CO
    摘要:Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.

    专利号:US-6562844-B2
    优先权日:1998-01-23
    标 题:Oxazolidinone combinatorial libraries, compositions and methods of preparation
    发明人:GORDEEV MIKHAIL F; LUEHR GARY W; PATEL DINESH V; NI ZHI-JIE; GORDON ERIC
    权利人:UPJOHN CO
    摘要:Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.

    专利号:US-9217012-B2
    优先权日:2009-04-08
    标题 :Inhibitors of protein tyrosine phosphatases
    发明人:ZHANG ZHONG-YIN; ZHANG SHENG
    权利人:ZHANG ZHONG-YIN; ZHANG SHENG; UNIV INDIANA RES & TECH CORP
    摘要:Disclosed herein are compounds that selectively inhibit members of the PTP family of enzymes. Synthesized compounds demonstrated selective inhibition of TC-PTP. Also provided are methods of using the compounds and formulations containing the compounds. Also described is a fluorescence-tagged combinatorial library synthesis and screening method. And methods of using these compounds to effect enzyme activity both in cells and in vitro as well as method of using these compounds to treat diseases in human and animals.

    专利号:US-7002020-B1
    优先权日:1998-01-23
    标题:Oxazolidinone combinatorial libraries, compositions and methods of preparation
    发明人:GORDEEV MIKHAIL F; LUEHR GARY W; PATEL DINESH V
    权利人:UPJOHN CO
    摘要:Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.

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    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:Nguyen, B. N.; Hii, K. K.; Szymański, W.; Janssen, D. B., Science of Synthesis: Stereoselective Synthesis, (2011) 1, 643.
    摘要:Bartsch, S.; Vogel, A., Science of Synthesis: Biocatalysis in Organic Synthesis, (2015) 2, 302.
    摘要:Lloyd, C. M.; Dowell, K. F.; Brittain, W. D. G., Science of Synthesis: Modern Strategies in Organofluorine Chemistry, (2025) 2.
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