CAS: 66280-25-9; (6R,7S,12As)-1,2,11,12-Tetramethoxy-6,7-Dimethyl-5,6,7,8-Tetrahydrodibenzo[a,C][8]Annulene-3,10-Diol

该化合物是天然化合物,主要来自Schisandra中国人植物的产物,以其传统医学特性著称;该化合物展示了复杂的分子结构,其特点是多芳香环和氢氧基,有助于其生物活动;Gomisin J对其潜在的药理效应,包括抗氧化剂,抗炎和...

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CAS号110397-81-4 (3aS,R-Biar)-3a... | CAS号61281-38-7 五味子甲素

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    主要参考文献

    1. Chen, D.-F., Zhang, S.-X., Xie, J.-X., et al. Anti-AIDS agents—XXVI. Structure-activity correlations of gomisin-G-related anti-HIV lignans from Kadsura interior and of related synthetic analogues. Bioorg. Med. Chem. 5(8), 1715-1723 (1997). 2. Oh, S.-Y., Kim, Y.H., Bae, D.S., et al. Anti-inflammatory effects of gomisin J, and Schisandrin C isolated from the fruit of Schisandra chinensis. Biosci. Biotechnol. Biochem. 74(2), 285-291 (2010). 3. Park, J.Y., Hoi, Y.W., Yun, J.W., et al. Gomisin J from Schisandra chinensis induces vascular relaxation via activation of endothelial nitric oxide synthase. Vascul. Pharmacol. 57(2-4), 124-130 (2012). 4. Jung, S., Moon, H.-I., Kim, S., et al. Anticancer activity of gomisin J from Schisandra chinensis fruit. Oncol. Rep. 41(1), 711-717 (2019).

    合成参考文献


    参考文献:10.1515/znb-2010-0201
    摘要:Ren R, Ci X, Li H, Luo G, Li R, Deng X. New Dibenzocyclooctadiene Lignans from Schisandra sphenanthera and Their Proinflammatory Cytokine Inhibitory Activities. 2010 Feb 01;65(2):1–8. doi: 10.1515/znb-2010-0201.
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