CAS: 64228-81-5; 2,2'-((Pentane-1,5-Diylbis(Oxy))Bis(3-Oxopropane-3,1-Diyl))Bis(1-(3,4-Dimethoxybenzyl)-6,7-Dimethoxy-2-Methyl-1,2,3,4-Tetrahydroisoquinolin-2-Ium) Benzenesulfonate

上下游产品

CAS号64228-78-0 阿曲库胺草酸盐 | CAS号80-18-2 苯磺酸甲酯 | CAS号93-40-3 3,4-二甲氧基苯乙酸 | CAS号139-76-4 N-(3,4-二甲氧基苯乙基)... | CAS号6957-27-3 3,4-二氢罂粟碱 | CAS号120-20-7 3,4-二甲氧基苯乙胺 | CAS号6429-04-5 四氢罂粟碱盐酸盐

阿曲库铵杂质c,苯磺酸甲酯 以85%的收率获得产物
参考文献:Stenlake,J. B.;Waigh,R. D.;Dewar,G. H.;Hughes,R.;Chapple,D. J.;Coker+,Eur. J. Med. Chem.-Chim. Ther.,1981,16,N 6,515-524
标题:Stenlake,J. B.;Waigh,R. D.;Dewar,G. H.;Hughes,R.;Chapple,D. J.;Coker+,Eur. J. Med. Chem.-Chim. Ther.,1981,16,N 6,515-524

专利信息

专利号:WO-0112817-A1
优先权日:1999-08-12
标题:Evolution and use of enzymes for combinathorial and medicinal chemistry
发明人：KREBBER CLAUS; DAVIS S CHRISTOPHER; DELCARDAYRE STEPHEN; SELIFONOV SERGEY A; HOWARD RUSSELL
权利人:MAXYGEN INC; LIU LU; KREBBER CLAUS; DAVIS S CHRISTOPHER; DELCARDAYRE STEPHEN; SELIFONOV SERGEY A; HOWARD RUSSELL
摘要:This invention provides libraries of recombinant derivatizing enzymes that are useful for biocatalytic synthesis of derivatives oforganic molecules, including lead compounds for pharmaceutical use. The recombinant derivatizing enzymes catalyze reactions such as modification or replacement of functional groups on the organicmolecules, or addition of chemical moieties onto preexisting functional groups. The use of recombinant enzyme libraries enables one to obtain enzymes that catalyze the formation of organic molecule derivatives that could not otherwise be made using only naturally occurring enzymes.

专利号:US-6030613-A
优先权日:1995-01-17
标题:Receptor specific transepithelial transport of therapeutics
发明人：BLUMBERG RICHARD S; SIMISTER NEIL E; LENCER WAYNE I
权利人:BRIGHAM & WOMENS HOSPITAL; UNIV BRANDEIS
摘要:The present invention relates in general to methods and products for initiating an immune response against an antigen, and in particular relates to transepithelial delivery of antigens to provoke tolerance and immunity. The present invention further relates to methods and products for the transepithelial delivery of therapeutics. In particular, the invention relates to methods and compositions for the delivery of therapeutics conjugated to a FcRn binding partner to intestinal epithelium, mucosal epithelium and epithelium of the lung. The present invention further relates to the synthesis, preparation and use of the FcRn binding partner conjugates as, or in, pharmaceutical compositions for oral systemic delivery of drugs and vaccines.

专利号:US-7547436-B2
优先权日:1995-01-17
标 题:Receptor specific transepithelial transport of therapeutics
发明人：BLUMBERG RICHARD S; LENCER WAYNE I; SIMISTER NEIL E
权利人:BRIGHAM & WOMENS HOSPITAL; UNIV BRANDEIS
摘要:The present invention relates in general to methods and products for initiating an immune response against an antigen, and in particular relates to transepithelial delivery of antigens to provoke tolerance and immunity. The present invention further relates to methods and products for the transepithelial delivery of therapeutics. In particular, the invention relates to methods and compositions for the delivery of therapeutics conjugated to a FcRn binding partner to intestinal epithelium, mucosal epithelium and epithelium of the lung. The present invention further relates to the synthesis, preparation and use of the FcRn binding partner conjugates as, or in, pharmaceutical compositions for oral systemic delivery of drugs and vaccines.

专利号:CN-215139938-U
优先权日:2021-07-08
标 题:Temperature control device for synthesis of atracurine besylate

专利号:WO-2023086696-A2
优先权日:2021-11-10
标 题:Apparatus and methods for continuous flow synthesis of cisatracurium

专利号:US-2014315720-A1
优先权日:2012-10-24
标 题 :Polysaccharide ester microspheres and methods and articles relating thereto
发明人：FALLON DENIS G; GARRETT THOMAS S; KIZER LAWTON E; ZAZZARA KAREN L; COMBS MICHAEL T; JOHNSON RICHARD K; DEHART GARY
权利人:CELANESE ACETATE LLC
摘要:A method for producing a polysaccharide ester microsphere may include forming a polysaccharide ester product from a polysaccharide synthesis, wherein the polysaccharide ester product comprises a polysaccharide ester and a solvent; diluting the polysaccharide ester product, thereby yielding a polysaccharide ester dope; and forming a plurality of polysaccharide ester microspheres from the polysaccharide ester dope. Suitable polysaccharides may include, but are not limited to, starch, cellulose, hemicellulose, algenates, chitosan, and any combination thereof. Esters thereof may be organic esters (e.g., acetate and the like), inorganic esters (e.g., sulfonates and the like), or combinations thereof. Further, the solids conent of the polysaccharide ester dope, in some instances, may be greater than about 16 wt %.