CAS: 5330-98-3; 2-Chloro-3-Nitrothiophene

该化合物是一种热循环芳烃化合物,其2位置用氯原子取代硫苯环,3位置用硝基组.该化合物是有机合成的多种中间体,特别是在制药,农用化学品和功能材料的制作方面;其反应式的氯和硝基替代体能够选择性地发挥作用,通过核循环替代或减少反应促进进一步的衍生.该硝基组的电子提取性增强了硫苯环的电光特性,使其在交叉相撞反应中有用.高纯度确保研究和工业应用的一贯性能.由于它具有潜在的回动性和敏感性,建议正确处理.

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CAS号89166-85-8 5-氯-4-硝基噻吩-2-甲酸 | CAS号58457-24-2 5-氯-4-硝基噻酚-2-磺酰氯 | CAS号142-04-1 苯胺盐酸盐 | CAS号78399-02-7 3-nitro-N-pheny... | CAS号85598-51-2 3-硝基噻吩-2-甲腈 | CAS号6286-32-4 2-Chloro-3,5-di...

合成工艺路线路线简述

    📜5-氯-4-硝基噻吩-2-磺酰氯置于硫酸,水体系中,化学反应生成 2-氯-3-硝基噻酚
    参考文献:Nitrothienols And Halogenated Nitrothiophenes
    标题:Nitrothienols And Halogenated Nitrothiophenes
    摘要:
    DOI:10.1021/ja01132A004

    海关参考信息

    专利信息


    专利号:US-6531470-B1
    优先权日:1998-01-23
    标题:Oxazolidinone combinatorial libraries, compositions and methods of preparation
    发明人:GORDEEV MIKHAIL F; LUEHR GARY W; PATEL DINESH V; NI ZHI-JIE; GORDON ERIC
    权利人:UPJOHN CO
    摘要:Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.

    专利号:US-6562844-B2
    优先权日:1998-01-23
    标 题:Oxazolidinone combinatorial libraries, compositions and methods of preparation
    发明人:GORDEEV MIKHAIL F; LUEHR GARY W; PATEL DINESH V; NI ZHI-JIE; GORDON ERIC
    权利人:UPJOHN CO
    摘要:Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.

    专利号:US-7002020-B1
    优先权日:1998-01-23
    标题:Oxazolidinone combinatorial libraries, compositions and methods of preparation
    发明人:GORDEEV MIKHAIL F; LUEHR GARY W; PATEL DINESH V
    权利人:UPJOHN CO
    摘要:Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.

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    合成参考文献


    参考文献:10.1007/978-3-030-29430-4_6
    摘要:Vogt N, Vogt J. Molecules with Four Carbon Atoms. 2019. In: Structure Data of Free Polyatomic Molecules.
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