CAS: 24410-19-3; Pyrido[2,3-D]Pyrimidin-4(1H)-One

相似化合物

155690-79-2 21038-66-4 1456547-92-4

上下游产品

吡啶并[2,3-D]嘧啶-2,4(1H,3H)-二酮 1H-Pyrido[2,3-D]Pyrimidine-2,4-Dione 21038-66-4
2-三氧代-2,3-二氢吡啶并[2,3-D]嘧啶-4(1H)-酮 2-Thioxo-2,3-Dihydropyrido/2,3-D/pyrimidin-4(1H)-One 37891-04-6

2-氨基烟酸置于potassium Phosphate,Copper(L) Iodide,氯化铵,1-羟基苯并三唑,盐酸-N-乙基-N'-(3-二甲氨基丙基)碳二亚胺,N,N-二异丙基乙胺,三苯基膦体系中,用 1,4-二氧六环,水,二甲基亚砜 用作溶剂,化学反应 35.0H,反应生成吡啶并[2,3-D]嘧啶-4(3H)-酮
参考文献:以 Brcf2Cooet 作为 C1 源的铜催化碳环化一般合成含氮杂环化合物
标题:以 Brcf2Cooet 作为 C1 源的铜催化碳环化一般合成含氮杂环化合物
摘要:已经开发出一种实用且高效的铜催化 2-官能化苯胺与溴二氟乙酸乙酯的碳环化反应.在此转化中,溴二氟乙酸乙酯通过四次裂解用作 C1 源.该反应可以得到多种含氮杂环化合物,且产率令人满意,官能团相容性优异.
Doi:10.1021/acs.Joc.3C02827

专利信息

专利号:US-3950160-A
优先权日:1972-09-27
标题:Inhibiting the growth of weeds with 2-substituted pyrdidopyimidines and salts thereof
发明人：ABU EL-HAJ MARWAN J; DOMINY BERYL WILLIAM
权利人:PFIZER
摘要:2-Substituted pyridopyrimidines and their alkali and alkylamine salts as herbicides, and processes for the synthesis of starting materials leading to the preparation thereof.

专利号:US-9540371-B2
优先权日:2013-04-29
标 题:Substituted quinazolin-4(3H)-ones, pyrido[3,4-d]pyrimidin-4(3H)-ones, pyrido[3,2-d]pyrimidin-4(3H)-ones and pyrido[2,3-d]pyrimidin-4(3H)-ones as positive allosteric modulators of muscarinic acetycholine receptor M1
发明人：LINDSLEY CRAIG W; CONN P JEFFREY; STAUFFER SHAUN R; PANARESE JOSEPH DAVID
权利人:UNIV VANDERBILT
摘要:In one aspect, the invention relates to 3-benzylquinazolin-4(3H)-one analogs, derivatives thereof, and related compounds, which are useful as positive allosteric modulators of the muscarinic acetylcholine receptor M 1 (mAChR M 1 ); synthesis methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating neurological and psychiatric disorders associated with muscarinic acetylcholine receptor dysfunction using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. Exemplary 3-benzylquinazolin-4(3H)-one compounds include compounds of formula (I):

专利号:US-9630962-B2
优先权日:2013-06-14
标 题:4-amino-6-(2,6-dichlorophenyl)-2-(phenylamino)-pyrido[2,3-d]pyrimidin-7(8H)-one derivatives, synthesis and uses thereof
发明人：BORRELL BILBAO JOSÉ IGNACIO; TEIXIDO CLOSA JORDI; PUIG DE LA BELLACASA CAZORLA RAIMON; COLOMER PUJOL DOLORS; ROUE GAEL; PÉREZ-GALÃ?N PATRICIA
权利人:INST QUÃ?MIC DE SARRIÃ? CETS FUNDACIÓ PRIVADA; HOSPITAL CLÃ?NIC DE BARCELONA; FUNDACIÓ CLINIC PER A LA RECERCA BIOMÈDICA (FCRB); INST D'INVESTIGACIONS BIOMÈDIQUES AUGUST PI I SUNYER; HOSPITAL CLINIC BARCELONA; FUNDACIÓ CLINIC PER A LA RECERCA BIOMÈDICA
摘要:The present invention is related to 4-amino-6-(2,6-dichlorophenyl)-2-(phenylamino)-pyrido[2,3-d]pyrimidin-7(8H)-one derivatives, to the preparation of such compounds, to pharmaceutical compositions comprising them, and to their use in the treatment and/or prevention of a non-Hodgkin's lymphoma.

专利号:US-3962264-A
优先权日:1972-09-27
标 题:Process for making 2-amino nicotinonitrile
发明人：ABU EL-HAJ MARWAN J; DOMINY BERYL WILLIAM
权利人:PFIZER
摘要:2-Substituted pyridopyrimidines and their alkali and alkylamine salts as herbicides, and processes for the synthesis of starting materials leading to the preparation thereof.

专利号:US-3917624-A
优先权日:1972-09-27
标题:Process for producing 2-amino-nicotinonitrile intermediates
发明人：ABU EL-HAJ MARWAN J; DOMINY BERYL WILLIAM
权利人:PFIZER
摘要:2-Substituted pyridopyrimidines and their alkali and alkylamine salts as herbicides, and processes for the synthesis of starting materials leading to the preparation thereof.

专利号:US-3862191-A
优先权日:1972-09-27
标 题 :Pyrido{8 2,3-d{9 pyrimidin-4(3H)-one
发明人：EL-HAJ MARWAN J ABU; DOMINY BERYL WILLIAM
权利人:PFIZER
摘要:2-Substituted pyridopyrimidines and their alkali and alkylamine salts as herbicides, and processes for the synthesis of starting materials leading to the preparation thereof.