📜α,α-二苯基-4-哌啶甲醇置于sodium Tetrahydroborate,Potassium Hydrogencarbonate体系中,用 甲醇,5,5-Dimethyl-1,3-Cyclohexadiene,水 用作溶剂,化学反应 12.5H,反应生成非索非那定杂质c
参考文献:Novel And Efficient Method For The Synthesis Of Racemic Fexofenadine
标题:Novel And Efficient Method For The Synthesis Of Racemic Fexofenadine
摘要:[image Omitted] Fexofenadine Is A Selective H1-Histamine Receptor Antagonist,Which Is An Attractive Alternative Treatment For Allergy Symptoms. An Efficient And Environmentally Friendly Synthetic Approach For The Preparation Of Fexofenadine Was Developed From Commercially Available Cumene. The Method Involves The Friedel-Craft'S Reaction,Substitution,Reduction,Bromination,And The Grignard Reaction.
Doi:10.1080/00397911.2010.502986