CAS: 17766-59-5; 4-Chloro-1-(3,4,5-Trimethoxyphenyl)Butan-1-One
该化合物是一种氯化氯酮衍生物,具有三甲基苯基替代物,该化合物因其功能性组群多功能性,作为合成药品,农用化学品和特殊化学品的一个潜在中间体,对合成有机化学具有兴趣;富电子的三氯苯基组的存在,增强了电子替代反应的再活性,而氯和氯酮功能提供了进一步的衍生机会.在受控条件下,其明确界定的结构和稳定性使其适合精确的合成应用.研究人员认为,这种化合物对于构建复杂的分子框架有用,特别是在药用化学中,因为三氯氧苯基霉菌在药理学上具有相关性.
- 英文名称4-Chloro-1-(3,4,5-Trimethoxyphenyl)Butan-1-One
- 中文名称4-氯-1-(3,4,5-三甲氧基苯基)丁-1-酮
- IUPAC名称(2S)-2-amino-4-((3,4-dichlorophenyl)(9H-fluoren-9-yl)methoxy)-4-oxobutanoic acid
- 其它别名(S)-3-(3,4-Dichloro-Phenyl)-2-(9H-Fluoren-9-Ylmethoxycarbonylamino)-Propionic Acid; N-Alpha-(9-Fluorenylmethoxycarbonyl)-L-3,4-Dichlorophenylalanine; N-Alpha-(9-Fluorenylmethyloxycarbonyl)-L-3,4-Dichlorophenylalanine; N-Alpha-Fmoc-3,4-Dichloro-L-Phenylalanine; Fmoc-(3,4-Di-Cl)-L-Phe-Oh; Fmoc-L-Phe(3,4-Cl2)-Oh; Fmoc-Phe(M,P-Cl2)-Oh
- CAS编号17766-59-5
- MFCD编号:MFCD00273473
- EINECS号:810-601-7
- 分子式:C24H19Cl2NO4分子量:456.33
- 产品CID: 904494
- 产品分类有机原料→分子砌块→芳环类化合物→苯类化合物
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64142-23-0 51490-01-8 170489-31-3MSDS等安全信息
欧盟法规
ECHA物质C&L通报合成工艺路线路线简述
海关参考信息
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专利信息
专利号:US-2022185846-A1
优先权日:2019-03-28
标 题:Methods for synthesizing beta-homoamino acids
发明人：MANTHATI SURESH KUMAR; BHANDARI ASHOK; MASJEDIZADEH MOHAMMAD REZA
权利人:PROTAGONIST THERAPEUTICS INC
摘要:Methods of making β-homoamino acids as intermediate for synthesis of peptide monmer and dimer α4β7-antagonists are disclosed. The disclosed methods include solid phase and solution phase methods.
专利号:US-8338565-B2
优先权日:2008-08-20
标 题 :Macrocyclic compounds for inhibition of tumor necrosis factor alpha
发明人：LEE JINBO; BOND JULIAN F; TERRETT NICHOLAS; FAVALORO JR FRANK G; WANG DANIEL; BRIGGS TIMOTHY F; SEIGAL BENJAMIN ADAM; SUN WEI-CHUAN; HALE STEPHEN P
权利人:LEE JINBO; BOND JULIAN F; TERRETT NICHOLAS; FAVALORO JR FRANK G; WANG DANIEL; BRIGGS TIMOTHY F; SEIGAL BENJAMIN ADAM; SUN WEI-CHUAN; HALE STEPHEN P; ENSEMBLE THERAPEUTICS CORP
摘要:Disclosed herein are macrocyclic compounds and methods for their synthesis and use. In particular, macrocyclic compounds are disclosed that modulate the activity of tumor necrosis factor alpha and/or are useful in the treatment of medical conditions, such as, rheumatoid arthritis, psoriasis, and asthma.
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品牌试剂参考报价(招募中)
📌 第三方产品分析报告
合成参考文献
合成方法参考DOI号:10.1021/jm00308a032
📝 需求与反馈
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