CAS: 103-95-7; 3-(4-Isopropylphenyl)-2-Methylpropanal

该化合物是一种合成芳香化合物,广泛用于香水和香味配方,其化学结构的特点是花粉,利冰般的香味,含有绿色和粉状的底色,使其成为香味,肥皂和家用产品中的多种成分.该化合物表现出极佳的稳定性和混合性,增强了花粉和木质配方,同时有助于长期的嗅觉特征.其低的挥发性确保了持续的香味释放,使之适合底部和中值.Cyclamen alderyde也因其与其他芳香化学物的兼容性而受到重视,使配方能够形成复杂和和谐的香味成分.根据应用情况,典型的使用水平从0.1%到5%不等.

结构式图片

相似化合物

80-54-6 38861-78-8 4756-19-8

欧盟法规

REACH注册ECHA物质C&L通报REACH预注册

上下游产品

CAS号78-85-3 2-甲基丙烯醛 | CAS号98-82-8 异丙基苯 | CAS号122-03-2 枯名醛 | CAS号4756-19-8 3-(p-cumenyl)-2... | CAS号831-97-0 4-isopropyl-alp... | CAS号6839-77-6 acetic acid 3-(... | CAS号56208-30-1 3t()-(4-isoprop... | CAS号855151-22-3 2,3-epoxy-4-(4-... | CAS号7149-24-8 cyclamen aldehy... | CAS号4756-19-8 3-(p-cumenyl)-2...

合成工艺路线路线简述

    4-异丙基苄氯置于sodium Hydroxide,乙醇,硫酸,Sodium Ethanolate,苯体系中,化学反应生成兔耳草醛
    参考文献:Synthesis Ofp-Isopropyls Methylhydrocinnamic Aldehyde
    标题:Synthesis Ofp-Isopropyls Methylhydrocinnamic Aldehyde
    摘要:
    Doi:10.1246/bcsj.16.413

    专利信息


    专利号:US-11220513-B2
    优先权日:2015-04-30
    标题:Chromium-mediated coupling and application to the synthesis of halichondrins
    发明人:KISHI YOSHITO; YAN WUMING; LI JINGWEI; LI ZHANJIE; YAHATA KENZO
    权利人:HARVARD COLLEGE
    摘要:The present invention provides unified synthesis of the C1-C19 building blocks of halichondrins and analogs thereof using selective coupling of poly-halogenated nucleophiles in chromium-mediated coupling reactions. The present invention also provides a practical and efficient synthesis of C20-C38 building blocks of halichondrins and analogs thereof. Also provided herein are general methods of selective activation and coupling of poly-halogenated analogs with an aldehyde. The provided coupling reactions are selective for halo-enone and halo-acetylenic ketal over vinyl halide and halide attached to a sp hybridized carbon. The provided efficient selective coupling reactions can allow easy access to the C1-C19 building blocks and C20-C38 building blocks of halichondrins and analogs thereof with limited or no purification or separation of the intermediates.

    专利号:US-7718578-B2
    优先权日:2003-03-31
    标 题 :Method of synthesis and testing of combinatorial libraries using microcapsules
    发明人:GRIFFITHS ANDREW DAVID; ABELL CHRIS; HOLLFELDER FLORIAN; MASTROBATTISTA ENRICO
    权利人:MEDICAL RES COUNCIL
    摘要:The invention describes a method for the synthesis of compounds comprising the steps of: (a) compartmentalizing two or more sets of primary compounds into microcapsules; such that a proportion of the microcapsules contains two or more compounds; and (b) forming secondary compounds in the microcapsules by chemical reactions between primary compounds from different sets. The invention further allows for the identification of compounds which bind to a target component of a biochemical system or modulate the activity of the target, and which is co-compartmentalized into the microcapsules.

    专利号:US-8901304-B1
    优先权日:2013-11-05
    标题:Benzo[D]imidazole derivatives of piperidine and piperazine
    发明人:ULLAH NISAR
    权利人:UNIV KING FAHD PET & MINERALS; KING ABDULAZIZ CITY SCI & TECH
    摘要:The benzo[d]imidazole derivatives of piperidine and piperazine are 5-piperazinyl and 5-piperadinyl-1H-benzo[d]imidazol-2(3H)-ones that exhibit D 2 and 5-HT 1A receptor binding affinities, making them suitable for use as the active ingredient of pharmaceuticals for the treatment of schizophrenia. The derivatives have the general formula: n nwhere X is carbon or nitrogen and R is a selected biaryl group, or a pharmaceutically acceptable salt thereof. The piperidinyl compounds are prepared by removal of the Boc group from tert-Butyl-4-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)piperidine-1-carboxylate. Subsequent reductive amination with a selected biarylaldehyde completes the synthesis of the 5-piperazinyl-1H-benzo[d]imidazol-2(3H)-ones. The piperazinyl compounds are prepared by preparation of the intermediate tert-Butyl 4-(3,4-diaminophenyl)piperazine-1-carboxylate. Removal of the Boc group and subsequent reductive amination with a selected biarylaldehyde completes the synthesis of the 5-piperazinyl-1H-benzo[d]imidazol-2(3H)-ones.

    专利号:RU-2035448-C1
    优先权日:1992-04-20
    标题:2-acetonyl-5,5-dimethyl-1,2,3,4,5,6,7,8-octahydronaphthalene as a component of perfumery composition, method of its synthesis, 2,6-dimethyl-2,6,10-tridecatriene-12-one as an intermediate product in synthesis of 2-acetonyl-5,5-dimethyl-1,2,3,4,5,6,7,8-octahydronaphthalene

    专利号:US-7501536-B2
    优先权日:2005-01-19
    标题 :Odorant compounds, synthesis method, and uses of said compounds
    发明人:JAUNKY PIOTR; MANE JEAN; SCHROEDER MARTIN
    权利人:MANE FILS V
    摘要:A compound of general formula (I) with or without the double bond illustrated by the dotted line. In formula (I), X is a CHO, CH2OH, CH2OC(O)R or CH(OR)2 group, and R represents a linear or branched C1-C5 alkyl or alkenyl chain. The synthesis method for the compound, and especially the 6,8-dimethyl-non-7-enal (1) prepared by the hydroformylation of the 5,7-dimethyl-octa-1,6-diene is also disclosed, as well as compositions containing the compounds of formula (I). Due to the odorant properties thereof, the compounds are highly useful in perfumery, especially for cosmetic products and household products.

    专利号:US-9925504-B2
    优先权日:2004-03-31
    标 题 :Compartmentalised combinatorial chemistry by microfluidic control
    发明人:GRIFFITHS ANDREW; WEITZ DAVID; AHN KEUNHO; LINK DARREN; BIBETTE JEROME
    权利人:GRIFFITHS ANDREW; WEITZ DAVID; AHN KEUNHO; LINK DARREN; BIBETTE JEROME; HARVARD COLLEGE; MEDICAL RES COUNCIL
    摘要:The invention describes a method for the synthesis of compounds comprising the steps of: (a) compartmentalizing two or more sets of primary compounds into microcapsules; such that a proportion of the microcapsules contains two or more compounds; and (b) forming secondary compounds in the microcapsules by chemical reactions between primary compounds from different sets; wherein one or both of steps (a) and (b) is performed under microfluidic control; preferably electronic microfluidic control The invention further allows for the identification of compounds which bind to a target component of a biochemical system or modulate the activity of the target, and which is co-compartmentalized into the microcapsules.
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    合成参考文献


    摘要:Rueda-Becerril, M.; Sammis, G. M., Science of Synthesis Knowledge Updates, (2017) 2, 215.
    摘要:Jie, X.; Su, W., Science of Synthesis, (2022) , 36.
    摘要:Chen, P.; Liu, G., Science of Synthesis: Catalytic Oxidation in Organic Synthesis, (2017) 1, 231.
    摘要:Food and Cosmetics Toxicology., 2(327), 1964
    摘要:S13 | EUCOSMETICS | Combined Inventory of Ingredients Employed in Cosmetic Products (2000) and Revised Inventory (2006) | DOI:10.5281/zenodo.2624118
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