CAS: 86847-64-5; N-(3-Formylpyridin-2-yl)Pivalamide
该化合物是有机化合物,具有独特的结构特征,含有一种以气态组替代的环,有助于其在有机合成中的活性及潜在应用.氨基功能组的存在表明,它可以参与氢结合,影响其溶解性和沸点.碳链上的两个甲基组提供了僵化障碍,可能影响化合物的再活动及与其他分子的相互作用.该化合物可能展示生物活动,使其对药用化学感兴趣.其具体特性,如熔点,沸点和溶性,将取决于分子相互作用和研究该物质的环境.
- 英文名称N-(3-Formylpyridin-2-yl)Pivalamide
- 中文名称2-(特戊酰氨基)吡啶-3-醛
- IUPAC名称N-(3-formylpyridin-2-yl)pivalamide
- 其它别名N-(3-甲基吡啶-2-基)棕榈酰胺; N-(3-Formyl-2-Pyridinyl)-2,2-Dimethylpropanamide
- CAS编号86847-64-5
- MFCD编号:MFCD01830170
- EINECS号:625-350-7
- 分子式:C11H14N2O2分子量:206.24
- 产品CID: 1871742
- 产品分类有机原料→分子砌块→芳杂环类化合物→吡啶类化合物
相似化合物
127446-34-8 125867-25-6 902837-38-1物理性质
MSDS等安全信息
- GHS象形图
- GHS符号GHS07;
注释: Exclamation mark - 危险类别特定目标器官毒性 - 单次接触 类别3
皮肤腐蚀/刺激 类别2
严重眼刺激 类别2
皮肤致敏 类别1 - 警示词Warning(警告)
- 危险描述H335 |可能引起呼吸道刺激.
H315 |造成皮肤刺激.
H319 |造成严重眼刺激.
H317 |可能引起皮肤过敏反应. - 防范说明P261-P264-P271-P272-P280-P302+P352-P304+P340-P362+P364-P405-P501
- 危险等级IRRITANT
- UN编号NONH for all modes of transport
- 危险品标志Xi
- 安全声明26-36/37
- 危险类别码36/37/38-43
- WGK Germany3
欧盟法规
ECHA物质C&L通报上下游产品
CAS号86847-59-8 2-特戊酰胺基吡啶 | CAS号68-12-2 N,N-二甲基甲酰胺 | CAS号4394-85-8 N-甲酰吗啉 | CAS号2591-86-8 1-甲酰哌啶 | CAS号109-72-8 正丁基锂 | CAS号3282-30-2 特戊酰氯 | CAS号504-29-0 2-氨基吡啶 | CAS号5174-90-3 2-氧-1,2-二氢-[1,8... | CAS号23612-57-9 2-氨基-3-羟甲基吡啶合成工艺路线路线简述
- 75-98-9 = 86847-64-5
反应条件:1.1 Reagents: Oxalyl Chloride Catalysts: Dimethylformamide Solvents: Dichloromethane; 0 °C2.1 Reagents: Triethylamine Solvents: Tetrahydrofuran; 0 °C; 1 H,0 °C -> Rt3.1 Reagents: Butyllithium Solvents: Tetrahydrofuran; -20 °C -> 0 °C; 2 H,0 °C3.2 0 °C; 2 H,0 °C -> Rt
标题:Regioselective Ketone α-Alkylation With Simple Olefins Via Dual Activation
作者:Mo,Fanyang; Et Al
参考文献:Science (Washington 日期:2014 卷标:345(6192) 页码:68-72]
86847-59-8 = 86847-64-5
反应条件:1.1 Reagents: Butyllithium Solvents: Tetrahydrofuran; -20 °C -> 0 °C; 2 H,0 °C1.2 0 °C; 2 H,0 °C -> Rt
标题:Regioselective Ketone α-Alkylation With Simple Olefins Via Dual Activation
作者:Mo,Fanyang; Et Al
参考文献:Science (Washington 日期:2014 卷标:345(6192) 页码:68-72]
= 86847-64-5
反应条件:1.1 Reagents: Triethylamine Solvents: Tetrahydrofuran; 0 °C; 1 H,0 °C -> Rt2.1 Reagents: Butyllithium Solvents: Tetrahydrofuran; -20 °C -> 0 °C; 2 H,0 °C2.2 0 °C; 2 H,0 °C -> Rt
标题:Regioselective Ketone α-Alkylation With Simple Olefins Via Dual Activation
作者:Mo,Fanyang; Et Al
参考文献:Science (Washington 日期:2014 卷标:345(6192) 页码:68-72
📜N-甲酰吗啉置于叔丁基锂体系中,用 乙醚,正戊烷,四氢呋喃 作为反应溶剂,化学反应 1.5H,以85%的收率获得产物2-(特戊酰氨基)吡啶-3-醛
参考文献:Ep1782811
标题:Ep1782811
海关参考信息
- 2912110000-甲醛
2912120000-乙醛
2933310010-吡啶
2924199090-其他无环酰胺 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:WO-2008022467-A1
优先权日:2006-08-25
标 题 :2-substituted azain doles and 2 substituted thienopyrroles, their precursors and novel processes for the preparation thereof
发明人：LAUTENS MARK; YUEN JOSEPHINE; FANG YUANQING
权利人:LAUTENS MARK; YUEN JOSEPHINE; FANG YUANQING
摘要:The present invention relates generally to processes for the chemical synthesis of azaindole and thienopyrrole compounds, in particular azaindole and thienopyrrole compounds that are substituted at the 2-position of the azaindole or thienopyrrole ring, and optionally at additional locations of the azaindole or thienopyrrole ring such as the 1- and/or 3-position, compounds prepared by such processes, and synthetic precursors of such processes. More particularly, the present invention relates to the preparation of 2- substituted azaindoles from an ortho-gem-dihalovinylaminopyridine or from an ortho- gem-dihalovinylaminopyridine N-oxide compound and an organoboron reagent using a palladium metal pre-catalyst, base and a ligand. The present invention also relates to the preparation of 2-substituted thienopyrroles from an ortho-gem-dihalovinylthiophene compound and an organoboron reagent using a palladium metal pre-catalyst, base and a ligand. The present invention also relates to processes for the production of ortho-gem- dihalovinylaminopyridines which are useful as starting materials in the production of 2- substituted azaindoles, and novel compounds prepared by the processes. The present invention also relates to processes for the production of ortho-gem-dihalovinylthiophenes which are useful as starting materials in the production of 2-substituted thienopyrroles, and novel compounds prepared by the processes. Formulae (V) and (VII).
专利号:US-6410526-B1
优先权日:1999-06-02
标题 :αv integrin receptor antagonists
发明人：DUGGAN MARK E; HARTMAN GEORGE D; MEISSNER ROBERT S; PERKINS JAMES J
权利人:MERCK & CO INC
摘要:The present invention relates to novel nonanoic acid derivatives, their synthesis, and their use as alphav integrin receptor antagonists. More particularly, the compounds of the present invention are antagonists of the integrin receptors alphavbeta3 and alphavbeta5 and are useful for inhibiting bone resorption, treating and preventing osteoporosis, and inhibiting vascular restenosis, diabetic retinopathy, macular degeneration, angiogenesis, atherosclerosis, inflammation, inflammatory arthritis, viral disease, cancer, and metastatic tumor growth.
专利号:US-7056909-B2
优先权日:2000-07-26
标题 :Alpha v integrin receptor antagonists
发明人：WANG JIABING
权利人:MERCK & CO INC
摘要:The present invention relates to novel chain-fluorinated alkanoic acid derivatives thereof, their synthesis, and their use as αv integrin receptor antagonists. More particularly, the compounds of the present invention are antagonists of the integrin receptors αvβ3 and/or αvβ5 and are useful for inhibiting bone resorption, treating and preventing osteoporosis, and inhibiting vascular restenosis, diabetic retinopathy, macular degeneration, angiogenesis, atherosclerosis, inflammation, inflammatory arthritis, viral disease, cancer, and metastatic tumor growth.
