CAS: 53-84-9; 1-((2R,3R,4S,5R)-5-((((((((2R,3S,4R,5R)-5-(6-Amino-9H-Purin-9-yl)-3,4-Dihydroxytetrahydrofuran-2-yl)Methoxy)(Hydroxy)Phosphoryl)Oxy)Oxidophosphoryl)Oxy)Methyl)-3,4-Dihydroxytetrahydrofuran-2-yl)-3-Carbamoylpyridin-1-Ium

上下游产品

H-benzo[g]pteridine-2,4-dione7,10-dimethyl-10H-benzo[g]pteridine-2,4-dione NADH -β-cyclodextrin2-(7α-O-10-methyl-7-isoalloxyazinyl)methyl-β-cyclodextrin -α-cyclodextrin2-(7α-O-10-methyl-7-isoalloxyazinyl)methyl-α-cyclodextrinacetaldehyde NADH nicotinamide mononucleotide ADP-ribofuranose

Alkaline Earth Salt Of/the/ Methylsulfuric Acid置于水,铜,双氧水体系中,化学反应生成 β-烟酰胺腺嘌呤二核苷酸
参考文献:Burton; Lamborg,Archives Of Biochemistry,1956,Vol. 62,P. 369,370
标题:Burton; Lamborg,Archives Of Biochemistry,1956,Vol. 62,P. 369,370

专利信息

专利号:US-12188072-B2
优先权日:2018-03-19
标题 :Compositions and methods for rapid in vitro synthesis of bioconjugate vaccines in vitro via production and N-glycosylation of protein carriers in detoxified prokaryotic cell lysates
发明人：JEWETT MICHAEL CHRISTOPHER; STARK JESSICA CAROL; DELISA MATTHEW P; JAROENTOMEECHAI THAPAKORN
权利人:UNIV NORTHWESTERN; UNIV CORNELL
摘要:Disclosed are methods, systems, components, and compositions for cell-free synthesis of glycosylated carrier proteins. The glycosylated carrier proteins may be utilized in vaccines, including anti-bacterial vaccines. The glycosylated carrier proteins may include a bacterial polysaccharide conjugated to a carrier, which may be utilized to generate an immune response in an immunized host against the polysaccharide conjugated to the carrier. The glycosylated carrier proteins may be synthesized in cell-free glycoprotein synthesis (CFGpS) systems using prokaryote cell lysates that are enriched in components for glycoprotein synthesis such as oligosaccharyltransferases (OSTs) and lipid-linked oligosaccharides (LLOs) including OSTs and LLOs associated with synthesis of bacterial O antigens.

专利号:US-9376461-B2
优先权日:2011-06-06
标 题:Non-enzymatic synthesis of O-acetyl-ADP-ribose and analogues thereof
发明人：KOPPETSCH KARSTEN; SZCZEPANKIEWICZ BRUCE G; PERNI ROBERT B
权利人:KOPPETSCH KARSTEN; SZCZEPANKIEWICZ BRUCE G; PERNI ROBERT B; GLAXOSMITHKLINE LLC
摘要:Provided herein is a simple, one-step, non-enzymatic synthesis of O-Acetyl-ADP-ribose (OAADPR) from NAD and sodium acetate in acetic acid. The extension of this reaction to other carboxylic acids, demonstrates that the reaction between NAD, and NAD analogs produces mixtures of the corresponding 2′- and 3′-carboxylic esters. Included are O-carboxyl-ADP-ribose compounds and corresponding methods of synthesis (e.g., O-propionyl-ADP-ribose, O-succinyl-ADP-ribose, O-malonyl-ADP-ribose), as well as non-adenosine nucleoside compounds.

专利号:WO-2023166160-A1
优先权日:2022-03-04
标 题:Process for synthesis of 1,4-dihydronicotinamide riboside (nrh) from nicotinamide-beta-riboside triacetate chloride (nra-cl)
发明人：MALKANNAGARI RAMANI; GUNDAPUNENI RAGHAVA RAO; BOHAN FRODE
权利人:BOHAN & CO AS
摘要:The present invention disclose novel process for synthesis of 1,4- dihydronicotinamide riboside (NRH). More particularly, the invention discloses a cost-effective synthesis of 1, 4-dihydronicotinamide riboside (NRH) from Nicotinamide-beta-riboside triacetate chloride (NRA-CI) in good yields and purity comprising the steps of a) reducing Nicotinamide-beta-riboside triacetate chloride (NRA-CI) in presence of non-chlorinated aprotic organic solvent and a reducing agent to obtain 1,4-dihydronicotinamide riboside triacetate (NRH-A); and b) deacetylating the 1,4-dihydronicotinamide riboside triacetate (NRHA) in presence of a base to obtain 1,4-dihydronicotinamide riboside(NRH)

专利号:US-2024247022-A1
优先权日:2021-05-04
标 题 :A Process for Synthesis of Nicotinamide Riboside Chloride (NRCL)
发明人：MALKANNAGARI RAMANI; GUNDAPUNENI RAGHAVA RAO; BOHAN FRODE
权利人:BOHAN & CO AS
摘要:The present invention discloses synthesis of nicotinamide riboside chloride (NRCI). More particularly, the present invention describes cost effective and industrially scalable process for the synthesis of NRCI in amorphous form.

专利号:US-2012208232-A1
优先权日:2009-07-15
标 题:Cell-Free Synthesis of Active Reprogramming Transcription Factors
发明人：YANG WILLIAM; PATEL KEDAR; GHEBREMARIAM YOHANNES T; LEE JI EUN; WONG HANN-CHUNG; COOKE JOHN P; SWARTZ JAMES ROBERT
权利人:YANG WILLIAM; PATEL KEDAR; GHEBREMARIAM YOHANNES T; LEE JI EUN; WONG HANN-CHUNG; COOKE JOHN P; SWARTZ JAMES ROBERT
摘要:Compositions and methods are provided for the cell-free synthesis of active reprogramming factor polypeptides. The reprogramming factors may be synthesized as fusion proteins comprising a permeant domain, such as polyarginme. The cell free-synthesis may be conducted at about 25 C in a bacterial cell extract from genetically alterd cells having decreased endogenous protease activity Further, the proteins may comprise a fusion partner which enhances solubility and may be refolded on a column.

专利号:US-2023091651-A1
优先权日:2021-09-20
标 题:Dietary supplement and method for synthesis of same
发明人：WYNN JASON R
权利人:StrongCell LLC
摘要:A dietary supplement and method for synthesis of the same are disclosed. In one embodiment of the method, an NADH component is provided that includes at least partially microencapsulated nicotinamide having nicotinamide blended with water. A supplement component, such as collagen, coenzyme Q10, vitamins, and minerals, is provided. A mixed component, which is a liquid, is formed by mixing the NADH component with the supplement component at ambient conditions. The mixed component is subjected to a fill production process.