专利号:US-8143308-B2 优先权日:2005-04-28 标题 :Synthesis of oligo/poly(catechins) and methods of use 发明人:BRUNO FERDINANDO F; KUMAR JAYANT; NAGARAJAN SUBHALAKSHMI; BRAUNHUT SUSAN J; NAGARAJAN RAMASWAMY; SAMUELSON LYNNE A; MCINTOSH DONNA; FOLEY KLAUDIA 权利人:BRUNO FERDINANDO F; KUMAR JAYANT; NAGARAJAN SUBHALAKSHMI; BRAUNHUT SUSAN J; NAGARAJAN RAMASWAMY; SAMUELSON LYNNE A; MCINTOSH DONNA; FOLEY KLAUDIA; UNIV MASSACHUSETTS LOWELL; US ARMY 摘要:A method for synthesizing a biocompatible, water-soluble oligo/polyflavanoid, includes polymerizing an optionally substituted flavanoid with a polymerization agent in the presence of a biocompatible polymerization solubilizer, thereby producing the biocompatible, soluble oligo/polyflavanoid. Also included is a biocompatible, soluble, oligo/polyflavanoid or a pharmaceutically acceptable salt, solvate, or complex thereof. Also included are methods of treating a subject for cancer, cardiac damage, viral infection, and obesity.
专利号:US-2009170928-A1 优先权日:2005-04-28 标题:Synthesis of oligo/poly(catechins) and methods of use
专利号:WO-2006116532-A2 优先权日:2005-04-28 标题:Synthesis of oligo/poly(catechins) and methods of use
专利号:CN-105906649-A 优先权日:2016-05-12 标 题 :A kind of method for asymmetric synthesis of chiral spirolide compound containing 5-hydroxyflavone unit
专利号:CN-105906649-B 优先权日:2016-05-12 标题:A kind of method for asymmetric synthesis of chiral spirolide compound containing 5-hydroxyflavone unit
参考文献:10.1021/np50001a002 摘要:Edwards JM, Raffauf RF, Le Quesne PW. Antineoplastic activity and cytotoxicity of flavones, isoflavones, and flavanones. J Nat Prod. 1979 Jan;42(1):85–91. doi: 10.1021/np50001a002.