CAS: 483-65-8; 7-Isopropyl-1-Methylphenanthrene

该化合物是多环芳烃(PAH),主要来源于有机材料的热降解,特别是在木材燃烧和某些自然物质的热解方面,其特点是分子式,通常由碳和氢原子组成,在包括引信环系统在内的特定结构中安排;Retene因其疏水特性而闻名,使其在水中相对溶解,但在有机溶剂中可溶解;这种化合物经常存在于环境样品中,特别是在沉积物和土壤中,可以用作人类活动的指标;Retene因其潜在的生态和健康影响而引起注意,因为一些PAHA是致癌的,其稳定性和持久性在环境中引起人们对其在生物系统和食物链中的积累的关切;总的来说,Retene是环境化学中的一种重要化合物,特别是在与污染和有机材料退化有关的研究中.

结构式图片

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20291-74-1 3674-74-6 883-20-5

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上下游产品

7-isopropyl-1-methyl-phenanthrene-9,10-dione abietinol abietic acid levopimaric acid1-methylphenanthrene 1-Methylnaphthalene 2-Methylnaphthalene trans-1-(4-Phenyl-styryl)-7-isopropyl-phenanthren

合成工艺路线路线简述

    📜脱氢松香酸置于溶剂黄146体系中,化学反应生成 惹烯
    参考文献:脱氢松香酸与乙烯酮生产试剂的热管反应.酰氯和脱氢枞酸的对称和混合酸酐衍生物的热解
    标题:脱氢松香酸与乙烯酮生产试剂的热管反应.酰氯和脱氢枞酸的对称和混合酸酐衍生物的热解
    摘要:脱氢枞酸 (1A) 与双乙烯酮,乙酸,乙酸酐,乙酸异丙烯酯,乙酰氯和丙酮在 450 oc 的热管中在 Vycor 棒上反应.脱氢枞酸酐(...
    DOI:10.1139/v73-484

    海关参考信息

    专利信息


    专利号:US-2003162992-A1
    优先权日:2001-12-14
    标 题 :Preparation of intermediates useful in the synthesis of antiviral nucleosides
    发明人:WATANABE KYOICHI A; DU JINFA
    摘要:The present invention is an efficient process for the manufacture of α-acyloxyacetaldehyde, a key intermediate in the synthesis of 1,3-oxathiolane and 1,3-dioxolane nucleosides.

    专利号:US-6432294-B1
    优先权日:2000-12-14
    标题 :Electrochemical activation of organic disulfides for electrophilic substitution
    发明人:GLASS RICHARD S; JOUIKOV VIATCHESLAV V; BOJKOVA NINA V
    权利人:UNIV ARIZONA
    摘要:Electrochemical oxidation of organic disulfides is conducted in an electrolytic solution containing an arene (e.g., anthracene, acenaphthylene, phenanthrene), and depending on the arene used and/or the product desired, an organic base (e.g., pyridine) to effect the synthesis of organothiated products in good yields.

    专利号:US-6713607-B2
    优先权日:1994-03-08
    标 题:Effector proteins of Rapamycin
    发明人:CAGGIANO THOMAS J; CHEN YANQIU; FAILLI AMEDEO A; MOLNAR-KIMBER KATHERINE L; NAKANISHI KOJI
    权利人:WYETH CORP; UNIV COLUMBIA
    摘要:This invention comprises novel Rapamycin-FKBP12 binding proteins of mammalian origin for identification, design and synthesis of immunomodulatory, anti-restenosis or anti-tumor agents, as well as fragments of the proteins and the DNA, cDNA, antisense RNA and DNA segments corresponding to the proteins. This invention also comprises methods for isolating the proteins and therapeutic uses related to the proteins.

    专利号:US-3948320-A
    优先权日:1975-03-14
    标 题:Method of in situ gasification, cooling and liquefaction of a subsurface coal formation
    发明人:TERRY RUEL C
    权利人:IN SITU TECHNOLOGY INC
    摘要:A method of liquefying a coal formation in situ wherein the coal formation has been preheated as by a coal gasification project, includes the steps of establishing injection and removal passages connecting the coal formation to the surface, injecting water having a temperature below the formation temperature into the formation to gradually lower the temperature of the formation while forming synthesis gas, injecting a solvent material, having the capability of dissolving the coal, into the formation after it has been reduced to the desired temperature, injecting synthesis gas into the formation to hydrogenate the coal, allowing the formation to subside as the coal is dissolved therein so that more surface area of coal is exposed to the solvent, and removing the admixture of coal and solvent material from the formation as a synthetic crude oil.

    专利号:US-6207838-B1
    优先权日:1999-04-30
    标 题 :Electrochemically generated organothiating reagents and their use
    发明人:GLASS RICHARD S; JOUIKOV VIATCHESLAV V
    权利人:UNIV ARIZONA
    摘要:Electrolysis of organic disulfides in liquid sulfur dioxide is used to obtain organothiating agents, which can then be reacted with appropriate substrates to effect the synthesis of organothioaromatic compounds efficiently and in high yields. With appropriate phenolic compounds, regioselective substitution occurs in which para substitution greatly exceeds ortho substitution.

    专利号:CA-2470202-A1
    优先权日:2001-12-14
    标 题 :Preparation of intermediates useful in the synthesis of antiviral nucleosides

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    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献


    1: Geier MC, James Minick D, Truong L, Tilton S, Pande P, Anderson KA, Teeguardan J, Tanguay RL. Systematic developmental neurotoxicity assessment of a representative PAH Superfund mixture using zebrafish. Toxicol Appl Pharmacol. 2018 Apr 6. pii: S0041-008X(18)30121-2. doi: 10.1016/j.taap.2018.03.029. [Epub ahead of print] doi: 10.1016/j.ecoenv.2018.02.045. Epub 2018 Feb 22. doi: 10.1016/j.scitotenv.2017.10.060. Epub 2017 Oct 20. doi: 10.1038/s41598-017-11024-3.
    5: Chlebowski AC, La Du JK, Truong L, Massey Simonich SL, Tanguay RL. Investigating the application of a nitroreductase-expressing transgenic zebrafish line for high-throughput toxicity testing. Toxicol Rep. 2017;4:202-210. doi: 10.1016/j.toxrep.2017.04.005. Epub 2017 Apr 27.
    6: Sarma SN, Blais JM, Chan HM. Neurotoxicity of alkylated polycyclic aromatic compounds in human neuroblastoma cells. J Toxicol Environ Health A. 2017;80(5):285-300. doi: 10.1080/15287394.2017.1314840. Epub 2017 Jun 9. doi: 10.1021/acs.est.7b00950. Epub 2017 May 19. doi: 10.1016/j.scitotenv.2017.03.256. Epub 2017 Apr 7. doi: 10.1016/j.jes.2016.02.022. Epub 2016 Jun 11. doi: 10.1021/acs.chemrestox.6b00457. Epub 2017 Mar 22.

    合成参考文献


    摘要:S109 | PARCEDC | List of 7074 potential endocrine disrupting compounds (EDCs) by PARC T4.2 | DOI:10.5281/zenodo.10944198
    参考文献:10.1007/bf02331424
    摘要:Crèvecoeur M, Cissé M, Xavier Albe, Hubert Greppin. Glucose-6-phosphate dehydrogenase activity in spinach as measured by image analysis: A new approach for plant enzyme histochemistry. Journal of Molecular Histology. 1996 Jan;28(1):25–32. doi: 10.1007/bf02331424.
    参考文献:10.1016/j.aquatox.2003.11.001
    摘要:Häkkinen J, Vehniäinen E, Oikari A. High sensitivity of northern pike larvae to UV-B but no UV-photoinduced toxicity of retene. Aquat Toxicol. 2004 Mar 10;66(4):393–404. doi: 10.1016/j.aquatox.2003.11.001.
    参考文献:10.1054/clnu.2001.0466
    摘要:Berard MP, Hankard R, Cynober L. Amino acid metabolism during total parenteral nutrition in healthy volunteers: evaluation of a new amino acid solution. Clin Nutr. 2001 Oct;20(5):407–14. doi: 10.1054/clnu.2001.0466.
    参考文献:10.1007/s10661-006-7667-5
    摘要:Fragoso NM, Hodson PV, Zambon S. Evaluation of an Exposure Assay to Measure Uptake of Sediment Pah by Fish. Environmental Monitoring and Assessment. 2006 May;116(1-3):481–511. doi: 10.1007/s10661-006-7667-5.
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